ES8206186A1 - Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes - Google Patents

Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes

Info

Publication number
ES8206186A1
ES8206186A1 ES505595A ES505595A ES8206186A1 ES 8206186 A1 ES8206186 A1 ES 8206186A1 ES 505595 A ES505595 A ES 505595A ES 505595 A ES505595 A ES 505595A ES 8206186 A1 ES8206186 A1 ES 8206186A1
Authority
ES
Spain
Prior art keywords
immunostimulating
klebsiella pneumoniae
medicaments
obtaining
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505595A
Other languages
English (en)
Other versions
ES505595A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES505595A0 publication Critical patent/ES505595A0/es
Publication of ES8206186A1 publication Critical patent/ES8206186A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/852—Klebsiella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Exhaust Silencers (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE GLICOPROTEINAS HIROSOLUBLES INMUNOESTIMULANTES, EXTRAIDAS DE "KLEBSIELLA PSEUMONIAE". CONSISTE EN EL TRATAMIENTO DE UNA DISOLUCION DE GLICOPROTEINAS, OBTENIDA A PARTIR DE CULTIVOS DE "KLEBSIELLA PSEUMONIAE", CON UN COMPUESTO DE AMONIO CUATERNARIO, TAL COMO BROMURO DE CETILTRIMETILAMONIO; CENTRIFUGACION, TRATAMIENTO EN FRIO DE LA DISOLUCION SALINA DE LAS GLICOPROTEINAS RESULTANTE CON UN ALCANOL INFERIOR, TAL COMO ETANOL, REDISOLUCION DEL PRECIPITADO FORMADO EN AGUA, DIALIZACION, LIOFILIZACION DE LA DISOLUCION RESULTANTE Y PURIFICACION POR REDISOLUCION Y FILTRACION SOBRE GEL. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE INFECCIONES POR BASTERIAS Y VIRUS, ENFERMEDADES DE PARASITOS, INFECCIONES TOXICAS, POSTHOSPITALARIAS Y POSTQUIRURGICAS.
ES505595A 1980-09-19 1981-09-18 Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes Expired ES8206186A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8020188A FR2490496A1 (fr) 1980-09-19 1980-09-19 Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant

Publications (2)

Publication Number Publication Date
ES505595A0 ES505595A0 (es) 1982-08-16
ES8206186A1 true ES8206186A1 (es) 1982-08-16

Family

ID=9246091

Family Applications (1)

Application Number Title Priority Date Filing Date
ES505595A Expired ES8206186A1 (es) 1980-09-19 1981-09-18 Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes

Country Status (16)

Country Link
US (2) US4412946A (es)
EP (1) EP0049182B1 (es)
JP (1) JPS5782322A (es)
AT (1) ATE6739T1 (es)
AU (1) AU546495B2 (es)
CA (1) CA1151544A (es)
DE (1) DE3162817D1 (es)
DK (1) DK157688C (es)
ES (1) ES8206186A1 (es)
FI (1) FI74474C (es)
FR (1) FR2490496A1 (es)
HU (1) HU185314B (es)
IE (1) IE51590B1 (es)
IL (1) IL63681A0 (es)
PT (1) PT73706B (es)
ZA (1) ZA816463B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540136A1 (fr) * 1983-01-28 1984-08-03 Roussel Uclaf Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques
FR2490496A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
US4870053A (en) * 1980-09-19 1989-09-26 Roussel Uclaf Novel compositions and processes
FR2523154A1 (fr) * 1982-03-09 1983-09-16 Fabre Sa Pierre Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant
FR2570081B1 (fr) * 1984-09-10 1987-01-09 Pf Medicament Polysaccharides membranaires utiles notamment comme medicament et procede pour leur preparation
FR2574429B1 (fr) * 1984-12-06 1987-12-11 Roussel Uclaf Acylglycannes extraits de klebsiella, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
JP2522945B2 (ja) * 1987-06-18 1996-08-07 呉羽化学工業株式会社 抗レトロウィルス剤
DE19836339B4 (de) * 1998-08-11 2011-12-22 N.V. Nutricia Kohlenhydratmischung
FR2842208B1 (fr) * 2002-07-10 2004-10-22 Lco Sante Extraits membranaires de klebsiella presentant des proprietes avantageuses, et procede de production de ces extraits
WO2004019699A1 (en) * 2002-08-30 2004-03-11 Campina B.V. Foaming ingredient and products containing the ingredient
EP2123282A3 (en) * 2003-10-24 2010-01-20 N.V. Nutricia Immunemodulating oligosaccharides
EP1597978A1 (en) 2004-05-17 2005-11-23 Nutricia N.V. Synergism of GOS and polyfructose
US8252769B2 (en) 2004-06-22 2012-08-28 N. V. Nutricia Intestinal barrier integrity
CA2570208A1 (en) * 2004-06-22 2005-12-29 N.V. Nutricia Improvement of barrier integrity in hiv patients
EP1723951A1 (en) * 2005-04-21 2006-11-22 N.V. Nutricia Nutritional supplement with oligosaccharides for a category of HIV patients
EP1721611A1 (en) * 2005-04-21 2006-11-15 N.V. Nutricia Nutritional supplement with oligosaccharides for a category of HIV patients
DE602006015042D1 (de) * 2005-04-21 2010-08-05 Nutricia Nv Nahrungsergänzungsmittel für hiv-patienten
WO2009096772A1 (en) * 2008-02-01 2009-08-06 N.V. Nutricia Composition for stimulating natural killer cell activity

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408440A (en) * 1966-09-26 1968-10-29 Procter & Gamble Method of preparing substantially cell-free somatic antigens
US3929994A (en) * 1969-05-20 1975-12-30 Roussel Uclaf Anti-inflammatory glycoprotein compositions and method of use
US3855197A (en) * 1969-05-20 1974-12-17 Cassenne Lab Sa Glycoproteins extracted from microorganisms
NL174267B (nl) * 1969-05-20 Roussel Uclaf Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat.
FR2088112B2 (es) * 1970-05-20 1975-01-10 Cassenne Lab Sa
BE795417A (fr) * 1972-02-15 1973-08-14 Roussel Uclaf Nouveaux composes d'origine-bacterienne et procede d'obtention
NL7308450A (es) * 1972-06-20 1973-12-27
US4001395A (en) * 1972-06-20 1977-01-04 Agence Nationale De Valorisation De La Recherche (Anvar) Hydrosoluble extracts of mycobacteria
FR2253499B1 (es) * 1973-12-10 1977-11-04 Fabre Sa Pierre
AR207237A1 (es) * 1974-02-25 1976-09-22 Thomas A Procedimiento para obtener extractos biologicos estables liofilizados solubles constituidos por complejos proteicos termorresistentes
FR2269961B1 (es) * 1974-05-06 1978-03-24 Anvar
FR2378855A1 (fr) * 1977-01-27 1978-08-25 Cassenne Lab Sa Nouvelles glycoproteines isolees d'hafnia, procede de preparation et application a titre de medicaments
FR2396020A1 (fr) * 1977-07-01 1979-01-26 Cassenne Lab Sa Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'hafnia, d'aerobacter cloacae et de klebsiella pneumoniae, procede de preparation et application a titre de medicaments de ces produits
FR2444464A1 (fr) * 1978-12-19 1980-07-18 Fabre Sa Pierre Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant
US4203970A (en) * 1979-03-05 1980-05-20 Merck & Co., Inc. Swine atropic rhinitis vaccine
FR2462477A1 (fr) * 1979-07-31 1981-02-13 Cassenne Lab Sa Nouvelles glycoproteines de klebsiella pneumoniae, procede d'obtention, application a titre de medicaments et compositions les renfermant
FR2490495A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines hydrosolubles immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2490496A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2523154A1 (fr) * 1982-03-09 1983-09-16 Fabre Sa Pierre Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant

Also Published As

Publication number Publication date
AU546495B2 (en) 1985-09-05
ES505595A0 (es) 1982-08-16
DE3162817D1 (en) 1984-04-26
FI812923L (fi) 1982-03-20
ATE6739T1 (de) 1984-04-15
ZA816463B (en) 1982-09-29
EP0049182B1 (fr) 1984-03-21
FR2490496A1 (fr) 1982-03-26
AU7545181A (en) 1982-03-25
EP0049182A1 (fr) 1982-04-07
IE812178L (en) 1982-03-19
FI74474B (fi) 1987-10-30
DK157688C (da) 1990-07-09
FI74474C (fi) 1988-02-08
IE51590B1 (en) 1987-01-21
PT73706B (fr) 1983-10-19
US4596709A (en) 1986-06-24
US4412946A (en) 1983-11-01
CA1151544A (fr) 1983-08-09
HU185314B (en) 1985-01-28
DK414981A (da) 1982-03-20
JPS5782322A (en) 1982-05-22
JPH0143760B2 (es) 1989-09-22
FR2490496B1 (es) 1983-05-27
PT73706A (fr) 1981-10-01
DK157688B (da) 1990-02-05
IL63681A0 (en) 1981-11-30

Similar Documents

Publication Publication Date Title
ES8206186A1 (es) Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes
MY103850A (en) Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them.
FI874398A0 (fi) Soetsaksprodukt och foerfarande foer dess framstaellning.
IE830227L (en) Pyrazolooxazines
ES8307098A1 (es) Un procedimiento para la preparacion de un nuevo antitrombosico a base de oligosacaridos y polisacaridos.
ES8203897A1 (es) Procedimiento para la obtencion de imidazoazoalquenamidas
IL112020A0 (en) Arylacetic acid derivatives, their preparation and their use as fungicides
ES8206185A1 (es) Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes
ES8203087A1 (es) Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos
ES483277A1 (es) Procedimiento para la obtencion de n-amino-3,4,5-tihidroxi- piperidinas
EP0141414A3 (en) Hair tonic composition

Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506