ES8206185A1 - Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes - Google Patents
Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantesInfo
- Publication number
- ES8206185A1 ES8206185A1 ES505594A ES505594A ES8206185A1 ES 8206185 A1 ES8206185 A1 ES 8206185A1 ES 505594 A ES505594 A ES 505594A ES 505594 A ES505594 A ES 505594A ES 8206185 A1 ES8206185 A1 ES 8206185A1
- Authority
- ES
- Spain
- Prior art keywords
- immunostimulating
- klebsiella pneumoniae
- hydrosoluble
- medicaments
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0266—Klebsiella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/26—Klebsiella (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/852—Klebsiella
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE GLICOPROTEINAS HIDROSOLUBLES INMUNOESTIMULANTES, EXTRAIDAS DE KLEBSIELLA PNEUMONIAE. CONSISTE EN EL TRATAMIENTO DE UNA DISOLUCION DE GLICOPROTEINAS OBTENIDAS POR DIAFILTRACION DE UN EXTRACTO DE LISADO DE CULTIVOS DE "KLEBSIELLA PNEUMONIAE", CON UN CONPUESTO DE AMONIO CUATERNARIO,SEPARACION DEL PRECIPITADO,TRATAMIENTO EN FRIO DE LA DISOLUCION ALCALINA DE LAS GLICOPROTEINAS OBTENIDA CON UN ALCANOL INFERIOR, SEPARACION DEL PRECIPITADO, DISOLUCION EN AGUA, EVENTUAL DIALIZACION Y, FINALMENTE, LIOFILIZACION DE LA DISOLUCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO O PREVENCION DE ENFERMEDADES INFECCIOSAS, TOXIINFECCIOSAS, INFECCIONES POSTHOSPIRALARIAS Y POSTQUIRURGICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8020187A FR2490495A1 (fr) | 1980-09-19 | 1980-09-19 | Nouvelles glycoproteines hydrosolubles immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
ES505594A0 ES505594A0 (es) | 1982-08-16 |
ES8206185A1 true ES8206185A1 (es) | 1982-08-16 |
Family
ID=9246090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505594A Expired ES8206185A1 (es) | 1980-09-19 | 1981-09-18 | Un procedimiento de preparacion de nuevas glicoproteinas hi-drosolubles inmunoestimulantes |
Country Status (16)
Country | Link |
---|---|
US (1) | US4356171A (es) |
EP (1) | EP0049181B1 (es) |
JP (1) | JPS5782321A (es) |
AT (1) | ATE8843T1 (es) |
AU (1) | AU546494B2 (es) |
CA (1) | CA1151545A (es) |
DE (1) | DE3165412D1 (es) |
DK (1) | DK157687C (es) |
ES (1) | ES8206185A1 (es) |
FI (1) | FI74475C (es) |
FR (1) | FR2490495A1 (es) |
HU (1) | HU185315B (es) |
IE (1) | IE51589B1 (es) |
IL (1) | IL63682A0 (es) |
PT (1) | PT73705B (es) |
ZA (1) | ZA815993B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2490496A1 (fr) * | 1980-09-19 | 1982-03-26 | Roussel Uclaf | Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
FR2523154A1 (fr) * | 1982-03-09 | 1983-09-16 | Fabre Sa Pierre | Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant |
FR2574429B1 (fr) * | 1984-12-06 | 1987-12-11 | Roussel Uclaf | Acylglycannes extraits de klebsiella, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
AT401398B (de) * | 1990-02-06 | 1996-08-26 | Plasser Bahnbaumasch Franz | Kontinuierlich verfahrbare gleisbaumaschine zum verdichten der schotterbettung |
AU746542B2 (en) * | 1998-03-18 | 2002-05-02 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
FR2809014A1 (fr) * | 2000-05-16 | 2001-11-23 | Pf Medicament | Utilisation d'une proteine ompa d'enterobacterie comme agent antimicrobien |
JP3687581B2 (ja) | 2001-08-31 | 2005-08-24 | セイコーエプソン株式会社 | 液晶パネル、その製造方法および電子機器 |
CH699786A2 (fr) * | 2008-10-31 | 2010-05-14 | Marie-Christine Dr Etienne | Médicament déstiné à traiter des infections. |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3408440A (en) * | 1966-09-26 | 1968-10-29 | Procter & Gamble | Method of preparing substantially cell-free somatic antigens |
US3855197A (en) * | 1969-05-20 | 1974-12-17 | Cassenne Lab Sa | Glycoproteins extracted from microorganisms |
NL174267B (nl) * | 1969-05-20 | Roussel Uclaf | Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat. | |
US3929994A (en) * | 1969-05-20 | 1975-12-30 | Roussel Uclaf | Anti-inflammatory glycoprotein compositions and method of use |
FR2088112B2 (es) * | 1970-05-20 | 1975-01-10 | Cassenne Lab Sa | |
BE795417A (fr) * | 1972-02-15 | 1973-08-14 | Roussel Uclaf | Nouveaux composes d'origine-bacterienne et procede d'obtention |
NL7308450A (es) * | 1972-06-20 | 1973-12-27 | ||
US4001395A (en) * | 1972-06-20 | 1977-01-04 | Agence Nationale De Valorisation De La Recherche (Anvar) | Hydrosoluble extracts of mycobacteria |
FR2253499B1 (es) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
AR207237A1 (es) * | 1974-02-25 | 1976-09-22 | Thomas A | Procedimiento para obtener extractos biologicos estables liofilizados solubles constituidos por complejos proteicos termorresistentes |
FR2269961B1 (es) * | 1974-05-06 | 1978-03-24 | Anvar | |
FR2378855A1 (fr) * | 1977-01-27 | 1978-08-25 | Cassenne Lab Sa | Nouvelles glycoproteines isolees d'hafnia, procede de preparation et application a titre de medicaments |
FR2396020A1 (fr) * | 1977-07-01 | 1979-01-26 | Cassenne Lab Sa | Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'hafnia, d'aerobacter cloacae et de klebsiella pneumoniae, procede de preparation et application a titre de medicaments de ces produits |
US4326053A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
FR2444464A1 (fr) * | 1978-12-19 | 1980-07-18 | Fabre Sa Pierre | Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant |
FR2462477A1 (fr) * | 1979-07-31 | 1981-02-13 | Cassenne Lab Sa | Nouvelles glycoproteines de klebsiella pneumoniae, procede d'obtention, application a titre de medicaments et compositions les renfermant |
-
1980
- 1980-09-19 FR FR8020187A patent/FR2490495A1/fr active Granted
-
1981
- 1981-08-27 IL IL63682A patent/IL63682A0/xx not_active IP Right Cessation
- 1981-08-28 ZA ZA815993A patent/ZA815993B/xx unknown
- 1981-09-10 US US06/300,928 patent/US4356171A/en not_active Expired - Fee Related
- 1981-09-11 DE DE8181401414T patent/DE3165412D1/de not_active Expired
- 1981-09-11 EP EP81401414A patent/EP0049181B1/fr not_active Expired
- 1981-09-11 AT AT81401414T patent/ATE8843T1/de not_active IP Right Cessation
- 1981-09-17 AU AU75450/81A patent/AU546494B2/en not_active Ceased
- 1981-09-18 HU HU812698A patent/HU185315B/hu unknown
- 1981-09-18 ES ES505594A patent/ES8206185A1/es not_active Expired
- 1981-09-18 PT PT73705A patent/PT73705B/pt unknown
- 1981-09-18 IE IE2177/81A patent/IE51589B1/en unknown
- 1981-09-18 JP JP56146462A patent/JPS5782321A/ja active Granted
- 1981-09-18 CA CA000386209A patent/CA1151545A/fr not_active Expired
- 1981-09-18 FI FI812924A patent/FI74475C/fi not_active IP Right Cessation
- 1981-09-18 DK DK414881A patent/DK157687C/da active
Also Published As
Publication number | Publication date |
---|---|
DK157687B (da) | 1990-02-05 |
AU7545081A (en) | 1982-03-25 |
FI74475C (fi) | 1988-02-08 |
HU185315B (en) | 1985-01-28 |
ES505594A0 (es) | 1982-08-16 |
JPH0148920B2 (es) | 1989-10-20 |
ZA815993B (en) | 1982-08-25 |
DE3165412D1 (en) | 1984-09-13 |
DK414881A (da) | 1982-03-20 |
AU546494B2 (en) | 1985-09-05 |
FR2490495B1 (es) | 1983-06-24 |
CA1151545A (fr) | 1983-08-09 |
JPS5782321A (en) | 1982-05-22 |
US4356171A (en) | 1982-10-26 |
PT73705A (fr) | 1981-10-01 |
FI812924L (fi) | 1982-03-20 |
IE51589B1 (en) | 1987-01-21 |
EP0049181A1 (fr) | 1982-04-07 |
IE812177L (en) | 1982-03-19 |
ATE8843T1 (de) | 1984-08-15 |
IL63682A0 (en) | 1981-11-30 |
FI74475B (fi) | 1987-10-30 |
FR2490495A1 (fr) | 1982-03-26 |
PT73705B (fr) | 1983-10-20 |
EP0049181B1 (fr) | 1984-08-08 |
DK157687C (da) | 1990-07-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960506 |