JPS5782322A - Novel immunostimulant sugar protein extracted from pneumonia bacillus,obtaining method, application as drug and composition containing same - Google Patents

Novel immunostimulant sugar protein extracted from pneumonia bacillus,obtaining method, application as drug and composition containing same

Info

Publication number
JPS5782322A
JPS5782322A JP56146463A JP14646381A JPS5782322A JP S5782322 A JPS5782322 A JP S5782322A JP 56146463 A JP56146463 A JP 56146463A JP 14646381 A JP14646381 A JP 14646381A JP S5782322 A JPS5782322 A JP S5782322A
Authority
JP
Japan
Prior art keywords
drug
application
composition containing
containing same
obtaining method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56146463A
Other languages
English (en)
Other versions
JPH0143760B2 (ja
Inventor
Zarisu Rune
Furansu Saaru Marii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS5782322A publication Critical patent/JPS5782322A/ja
Publication of JPH0143760B2 publication Critical patent/JPH0143760B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/852Klebsiella
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Exhaust Silencers (AREA)
JP56146463A 1980-09-19 1981-09-18 Novel immunostimulant sugar protein extracted from pneumonia bacillus,obtaining method, application as drug and composition containing same Granted JPS5782322A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8020188A FR2490496A1 (fr) 1980-09-19 1980-09-19 Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant

Publications (2)

Publication Number Publication Date
JPS5782322A true JPS5782322A (en) 1982-05-22
JPH0143760B2 JPH0143760B2 (ja) 1989-09-22

Family

ID=9246091

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56146463A Granted JPS5782322A (en) 1980-09-19 1981-09-18 Novel immunostimulant sugar protein extracted from pneumonia bacillus,obtaining method, application as drug and composition containing same

Country Status (16)

Country Link
US (2) US4412946A (ja)
EP (1) EP0049182B1 (ja)
JP (1) JPS5782322A (ja)
AT (1) ATE6739T1 (ja)
AU (1) AU546495B2 (ja)
CA (1) CA1151544A (ja)
DE (1) DE3162817D1 (ja)
DK (1) DK157688C (ja)
ES (1) ES505595A0 (ja)
FI (1) FI74474C (ja)
FR (1) FR2490496A1 (ja)
HU (1) HU185314B (ja)
IE (1) IE51590B1 (ja)
IL (1) IL63681A0 (ja)
PT (1) PT73706B (ja)
ZA (1) ZA816463B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58164514A (ja) * 1982-03-09 1983-09-29 ピエ−ル・フア−ブル・ソシエテ・アノニム 免疫刺激性プロテオグリカンおよびその製造方法
JPS63316726A (ja) * 1987-06-18 1988-12-26 Kureha Chem Ind Co Ltd 抗レトロウィルス剤

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870053A (en) * 1980-09-19 1989-09-26 Roussel Uclaf Novel compositions and processes
FR2490496A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2540136A1 (fr) * 1983-01-28 1984-08-03 Roussel Uclaf Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques
FR2570081B1 (fr) * 1984-09-10 1987-01-09 Pf Medicament Polysaccharides membranaires utiles notamment comme medicament et procede pour leur preparation
FR2574429B1 (fr) * 1984-12-06 1987-12-11 Roussel Uclaf Acylglycannes extraits de klebsiella, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
DE19836339B4 (de) * 1998-08-11 2011-12-22 N.V. Nutricia Kohlenhydratmischung
FR2842208B1 (fr) * 2002-07-10 2004-10-22 Lco Sante Extraits membranaires de klebsiella presentant des proprietes avantageuses, et procede de production de ces extraits
EP1538924B1 (en) * 2002-08-30 2007-09-26 Campina B.V. Foaming ingredient and products containing the ingredient
CN101987107A (zh) * 2003-10-24 2011-03-23 努特里奇亚有限公司 免疫调节性寡糖
EP1597978A1 (en) 2004-05-17 2005-11-23 Nutricia N.V. Synergism of GOS and polyfructose
US8252769B2 (en) 2004-06-22 2012-08-28 N. V. Nutricia Intestinal barrier integrity
EP1723951A1 (en) * 2005-04-21 2006-11-22 N.V. Nutricia Nutritional supplement with oligosaccharides for a category of HIV patients
MXPA06015071A (es) * 2004-06-22 2007-08-06 Nutricia Nv Mejoramiento de la integridad de barrera con acidos grasos en pacientes con vih.
EP1721611A1 (en) * 2005-04-21 2006-11-15 N.V. Nutricia Nutritional supplement with oligosaccharides for a category of HIV patients
PL1871181T5 (pl) * 2005-04-21 2017-10-31 Nutricia Nv Suplement odżywczy dla pacjentów z HIV
WO2009096772A1 (en) * 2008-02-01 2009-08-06 N.V. Nutricia Composition for stimulating natural killer cell activity

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408440A (en) * 1966-09-26 1968-10-29 Procter & Gamble Method of preparing substantially cell-free somatic antigens
US3929994A (en) * 1969-05-20 1975-12-30 Roussel Uclaf Anti-inflammatory glycoprotein compositions and method of use
US3855197A (en) * 1969-05-20 1974-12-17 Cassenne Lab Sa Glycoproteins extracted from microorganisms
NL174267B (nl) * 1969-05-20 Roussel Uclaf Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat.
FR2088112B2 (ja) * 1970-05-20 1975-01-10 Cassenne Lab Sa
BE795417A (fr) * 1972-02-15 1973-08-14 Roussel Uclaf Nouveaux composes d'origine-bacterienne et procede d'obtention
US4001395A (en) * 1972-06-20 1977-01-04 Agence Nationale De Valorisation De La Recherche (Anvar) Hydrosoluble extracts of mycobacteria
NL7308450A (ja) * 1972-06-20 1973-12-27
FR2253499B1 (ja) * 1973-12-10 1977-11-04 Fabre Sa Pierre
AR207237A1 (es) * 1974-02-25 1976-09-22 Thomas A Procedimiento para obtener extractos biologicos estables liofilizados solubles constituidos por complejos proteicos termorresistentes
FR2269961B1 (ja) * 1974-05-06 1978-03-24 Anvar
FR2378855A1 (fr) * 1977-01-27 1978-08-25 Cassenne Lab Sa Nouvelles glycoproteines isolees d'hafnia, procede de preparation et application a titre de medicaments
FR2396020A1 (fr) * 1977-07-01 1979-01-26 Cassenne Lab Sa Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'hafnia, d'aerobacter cloacae et de klebsiella pneumoniae, procede de preparation et application a titre de medicaments de ces produits
FR2444464A1 (fr) * 1978-12-19 1980-07-18 Fabre Sa Pierre Proteoglycanes bacteriens purifies, procede pour leur preparation et vaccin les contenant
US4203970A (en) * 1979-03-05 1980-05-20 Merck & Co., Inc. Swine atropic rhinitis vaccine
FR2462477A1 (fr) * 1979-07-31 1981-02-13 Cassenne Lab Sa Nouvelles glycoproteines de klebsiella pneumoniae, procede d'obtention, application a titre de medicaments et compositions les renfermant
FR2490495A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines hydrosolubles immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2490496A1 (fr) * 1980-09-19 1982-03-26 Roussel Uclaf Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant
FR2523154A1 (fr) * 1982-03-09 1983-09-16 Fabre Sa Pierre Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58164514A (ja) * 1982-03-09 1983-09-29 ピエ−ル・フア−ブル・ソシエテ・アノニム 免疫刺激性プロテオグリカンおよびその製造方法
JPH0587519B2 (ja) * 1982-03-09 1993-12-16 Fabre Sa Pierre
JPS63316726A (ja) * 1987-06-18 1988-12-26 Kureha Chem Ind Co Ltd 抗レトロウィルス剤

Also Published As

Publication number Publication date
HU185314B (en) 1985-01-28
IE812178L (en) 1982-03-19
AU7545181A (en) 1982-03-25
FI74474B (fi) 1987-10-30
AU546495B2 (en) 1985-09-05
EP0049182B1 (fr) 1984-03-21
DK414981A (da) 1982-03-20
CA1151544A (fr) 1983-08-09
IL63681A0 (en) 1981-11-30
PT73706A (fr) 1981-10-01
FI812923L (fi) 1982-03-20
FR2490496B1 (ja) 1983-05-27
ES8206186A1 (es) 1982-08-16
ZA816463B (en) 1982-09-29
PT73706B (fr) 1983-10-19
ATE6739T1 (de) 1984-04-15
JPH0143760B2 (ja) 1989-09-22
DK157688B (da) 1990-02-05
DE3162817D1 (en) 1984-04-26
EP0049182A1 (fr) 1982-04-07
US4412946A (en) 1983-11-01
ES505595A0 (es) 1982-08-16
US4596709A (en) 1986-06-24
IE51590B1 (en) 1987-01-21
FR2490496A1 (fr) 1982-03-26
FI74474C (fi) 1988-02-08
DK157688C (da) 1990-07-09

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