ES8106407A1 - Procedimiento para el tratamiento de superficies hidrofobas - Google Patents

Procedimiento para el tratamiento de superficies hidrofobas

Info

Publication number
ES8106407A1
ES8106407A1 ES494356A ES494356A ES8106407A1 ES 8106407 A1 ES8106407 A1 ES 8106407A1 ES 494356 A ES494356 A ES 494356A ES 494356 A ES494356 A ES 494356A ES 8106407 A1 ES8106407 A1 ES 8106407A1
Authority
ES
Spain
Prior art keywords
proteins
denaturization
utilization
manufacture
aqueous solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494356A
Other languages
English (en)
Spanish (es)
Other versions
ES494356A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2917535A external-priority patent/DE2917535C2/de
Priority claimed from DE19792952119 external-priority patent/DE2952119A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES494356A0 publication Critical patent/ES494356A0/es
Publication of ES8106407A1 publication Critical patent/ES8106407A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES494356A 1979-04-30 1980-08-19 Procedimiento para el tratamiento de superficies hidrofobas Expired ES8106407A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2917535A DE2917535C2 (de) 1979-04-30 1979-04-30 Gegen Denaturierung beständige Insulinlösungen
DE19792952119 DE2952119A1 (de) 1979-12-22 1979-12-22 Gegen denaturierung bestaendige, waessrige protein-loesungen

Publications (2)

Publication Number Publication Date
ES494356A0 ES494356A0 (es) 1981-07-16
ES8106407A1 true ES8106407A1 (es) 1981-07-16

Family

ID=25778936

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494356A Expired ES8106407A1 (es) 1979-04-30 1980-08-19 Procedimiento para el tratamiento de superficies hidrofobas

Country Status (11)

Country Link
US (1) US4885164A (esLanguage)
EP (1) EP0018609B1 (esLanguage)
AU (1) AU535040B2 (esLanguage)
CA (1) CA1146069A (esLanguage)
DE (1) DE3064888D1 (esLanguage)
DK (1) DK160459C (esLanguage)
EG (1) EG15017A (esLanguage)
ES (1) ES8106407A1 (esLanguage)
FI (1) FI70671C (esLanguage)
GR (1) GR67209B (esLanguage)
IL (1) IL59933A (esLanguage)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1011126A1 (ru) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Средство дл лечени сахарного диабета
FI78616C (fi) * 1982-02-05 1989-09-11 Novo Industri As Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt.
DE3380726D1 (en) * 1982-06-24 1989-11-23 Japan Chem Res Long-acting composition
US4457916A (en) * 1982-08-31 1984-07-03 Asahi Kasei Kogyo Kabushiki Kaisha Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
DE3325223A1 (de) * 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
CA1244347A (en) * 1984-05-29 1988-11-08 Eddie H. Massey Stabilized insulin formulations
DE3443877A1 (de) * 1984-06-09 1985-12-12 Hoechst Ag Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung
WO1989007945A1 (en) * 1988-02-26 1989-09-08 Genentech, Inc. Human relaxin formulation
US5981485A (en) * 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
IL87055A (en) * 1988-07-08 1994-06-24 Illana Gozes Conjugates of vasoactive intestinal peptide (vip) and of fragments thereof and pharmaceutical compositions comprising them
US5447912A (en) * 1989-09-18 1995-09-05 Senetek, Plc Erection-inducing methods and compositions
US5830452A (en) * 1990-11-20 1998-11-03 Chiron Corporation Method for enhancing the anti-tumor therapeutic index of interleukin-2
DE19722950A1 (de) * 1997-05-31 1998-12-03 Huels Chemische Werke Ag Renaturierung von Eiweißstoffen
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
ATE220558T1 (de) 1997-11-22 2002-08-15 Roche Diagnostics Gmbh Verbessertes verfahren zur stabilisierung von proteinen
WO2002067969A2 (en) 2001-02-21 2002-09-06 Medtronic Minimed, Inc. Stabilized insulin formulations
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
US6737401B2 (en) * 2001-06-28 2004-05-18 Metronic Minimed, Inc. Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
KR101784231B1 (ko) 2008-06-20 2017-11-08 노파르티스 아게 응집이 감소된 면역글로불린
LT3228320T (lt) 2008-10-17 2020-03-10 Sanofi-Aventis Deutschland Gmbh Insulino ir glp-1 agonisto derinys
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
PE20121362A1 (es) 2009-11-13 2012-10-17 Sanofi Aventis Deutschland Composicion farmaceutica que comprende despro36exendina-4(1-39)-lys6-nh2, insulina gly(a21)-arg(b31)-arg(b32) y metionina
KR101772372B1 (ko) 2009-11-13 2017-08-29 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
NZ599295A (en) 2009-11-25 2014-06-27 Boehringer Ingelheim Int Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011121559A2 (en) 2010-03-31 2011-10-06 Universite De Geneve Stabilized antibody preparations and uses thereof
JP2013528570A (ja) 2010-03-31 2013-07-11 ユニベルシテ ドゥ ジュネーブ 安定化された抗体調製物およびその使用
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
EP2611458B1 (en) 2010-08-30 2016-09-21 Sanofi-Aventis Deutschland GmbH Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
AU2012300978B2 (en) 2011-08-29 2017-04-27 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
BR112016023932B1 (pt) 2014-05-07 2022-11-29 Boehringer Ingelheim International Gmbh Nebulizador
DK3139984T3 (da) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Forstøver
EP3139979B1 (en) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Unit, nebulizer and method
HRP20230470T1 (hr) 2014-12-12 2023-07-21 Sanofi-Aventis Deutschland Gmbh Formulacija fiksnog omjera inzulin glargin/liksisenatid
AR102869A1 (es) 2014-12-16 2017-03-29 Lilly Co Eli Composiciones de insulina de rápida acción
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
JO3749B1 (ar) 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
NZ758298A (en) 2017-06-01 2022-11-25 Lilly Co Eli Rapid-acting insulin compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2212695A1 (de) * 1972-03-16 1973-09-20 Hoechst Ag Verfahren zur reinigung von insulin und insulinderivaten
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
GB1554157A (en) * 1975-06-13 1979-10-17 Takeda Chemical Industries Ltd Stable insulin preparation for intra nasal administration
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
GB1563311A (en) * 1975-09-26 1980-03-26 Yamanouchi Pharma Co Ltd Pharmaceutical composition of insulin for rectal use
DE3325223A1 (de) * 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
CA1244347A (en) * 1984-05-29 1988-11-08 Eddie H. Massey Stabilized insulin formulations

Also Published As

Publication number Publication date
EP0018609B1 (de) 1983-09-21
FI70671B (fi) 1986-06-26
EG15017A (en) 1985-12-31
ES494356A0 (es) 1981-07-16
FI801361A7 (fi) 1980-10-31
IL59933A0 (en) 1980-06-30
US4885164A (en) 1989-12-05
AU5787780A (en) 1980-11-06
GR67209B (esLanguage) 1981-06-24
DK160459B (da) 1991-03-18
DK185180A (da) 1980-10-31
CA1146069A (en) 1983-05-10
FI70671C (fi) 1986-10-06
IL59933A (en) 1984-06-29
DE3064888D1 (en) 1983-10-27
DK160459C (da) 1991-08-26
EP0018609A1 (de) 1980-11-12
AU535040B2 (en) 1984-03-01

Similar Documents

Publication Publication Date Title
ES8106407A1 (es) Procedimiento para el tratamiento de superficies hidrofobas
SE9401406L (sv) Farmaceutiska produkter för att bota tumörsjukdomar samt förfarande för framställning av desamma
HUT44793A (en) Process for production of 19-nor or 19-nor-d-homo stereoids substituated in position 11-beta by alkinylphenil group and medical preparatives containing them as active substance
ATE2113T1 (de) Verfahren zur herstellung von festen arzneimitteln mit troepfchenfoermig aufgebrachten wirkstoffen.
JPS57194787A (en) Culture medium for animal cell
DE3572179D1 (en) Blood coagulation inhibiting proteins, process for preparing them and their use
DE3382387D1 (de) Loesungen von aminosaeuren zur parenteralen naehrung sowie dosierverfahren und verwendung.
EP0155387A3 (en) Fibronolytically active hybrid protein, process for its preparation and pharmaceutical composition
DK235584D0 (da) Fremgangsmaade til fremstilling af et valleprodukt
ES2065911T3 (es) Produccion de proteinas en formas activas.
HUT45021A (en) Process for production of insecticides and acaricides containing pirasoline-derivatives as active substance and process for production of the active substances
GB1441751A (en) Purification of albumin by thermocoagulation
ATE96167T1 (de) Verfahren zur kristallisation von enzymen.
EP0216742A3 (en) Growth factors
PT87658A (pt) Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet loesung enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin
DK579185D0 (da) Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf
KR890006251A (ko) 고-순도의, 바이러스로부터 보호된 생물학적 활성 트랜스페린 제제의 제조방법
EP0214017A3 (en) Use of n,n,-dimethylbiguanid p-chorophenoxyacetate in the treatment of neuropathies and nerval degeneration
ES8607916A1 (es) Un procedimiento para la preparacion de medicamentos influenciadores de la circulacion sanguinea, que contienen compuestos de bis (carboxamida)
ATE26986T1 (de) Verfahren zur loesung von peptiden und proteinen, hierdurch erhaltene loesungen und deren verwendung.
EP0188262A3 (en) Process for the isolation of chicken egg white cystatine, antiviral agents containing it and its use as viral protease inhibitor
JPS57193494A (en) Method of purifying or concentrating biologically active protein and drug therefor
AU2740384A (en) Inactivation of viruses in virus containing protein samples
CH609863A5 (en) Cosmetic treatment process and products enabling it to be carried out
ATE3974T1 (de) Verfahren zur herstellung von 4,4'-dinitrostilben-2,2'-disulfonsaeure und deren salzen und deren verwendung.