DK579185D0 - Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf - Google Patents

Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf

Info

Publication number
DK579185D0
DK579185D0 DK579185A DK579185A DK579185D0 DK 579185 D0 DK579185 D0 DK 579185D0 DK 579185 A DK579185 A DK 579185A DK 579185 A DK579185 A DK 579185A DK 579185 D0 DK579185 D0 DK 579185D0
Authority
DK
Denmark
Prior art keywords
pyrrolobenzimidazoles
medicines
preparing
contents
present
Prior art date
Application number
DK579185A
Other languages
English (en)
Other versions
DK579185A (da
Inventor
Alfred Mertens
Jens-Peter Hoelck
Wolfgang Kampe
Bernd Mueller-Beckmann
Klaus Strein
Wolfgang Schaumann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK579185D0 publication Critical patent/DK579185D0/da
Publication of DK579185A publication Critical patent/DK579185A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK579185A 1984-12-14 1985-12-13 Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf DK579185A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445669 DE3445669A1 (de) 1984-12-14 1984-12-14 Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK579185D0 true DK579185D0 (da) 1985-12-13
DK579185A DK579185A (da) 1986-06-15

Family

ID=6252801

Family Applications (1)

Application Number Title Priority Date Filing Date
DK579185A DK579185A (da) 1984-12-14 1985-12-13 Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf

Country Status (16)

Country Link
US (2) US4710510A (da)
EP (1) EP0186010B1 (da)
JP (1) JPS61158984A (da)
AT (1) ATE49970T1 (da)
AU (1) AU580822B2 (da)
CA (1) CA1262908A (da)
CS (1) CS276403B6 (da)
DD (1) DD242045A5 (da)
DE (2) DE3445669A1 (da)
DK (1) DK579185A (da)
ES (1) ES8702409A1 (da)
FI (1) FI79318C (da)
GR (1) GR852979B (da)
HU (1) HU194241B (da)
SU (1) SU1440348A3 (da)
ZA (1) ZA859382B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3626664A1 (de) * 1986-08-07 1988-02-11 Boehringer Mannheim Gmbh Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3639466A1 (de) * 1986-11-18 1988-05-19 Thomae Gmbh Dr K Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3642315A1 (de) * 1986-12-11 1988-06-23 Boehringer Mannheim Gmbh Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3701277A1 (de) * 1987-01-17 1988-07-28 Boehringer Mannheim Gmbh Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3740985A1 (de) * 1987-12-03 1989-06-15 Boehringer Mannheim Gmbh Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation
DE3855327D1 (de) * 1987-12-30 1996-07-04 Orion Yhtymae Oy Heterocyclische Verbindungen
US4963677A (en) * 1987-12-30 1990-10-16 Orion Corporation Ltd. Heterocyclic lactam compounds
DE3803775A1 (de) * 1988-02-09 1989-08-17 Boehringer Mannheim Gmbh Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
JP2004529110A (ja) * 2001-03-06 2004-09-24 アストラゼネカ アクチボラグ 脈管損傷活性を有するインドール誘導体
WO2002072549A1 (en) * 2001-03-12 2002-09-19 Millennium Pharmaceuticals, Inc. Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
CA2553968A1 (en) * 2004-01-23 2005-08-11 Amgen Inc. Vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain
JP6116693B2 (ja) 2012-09-13 2017-04-19 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Cns障害の処置のための2−オキソ−2,3−ジヒドロ−インドール
ES2896400T3 (es) 2014-08-01 2022-02-24 Nuevolution As Compuestos activos frente a bromdominios
GB201709456D0 (en) * 2017-06-14 2017-07-26 Ucb Biopharma Sprl Therapeutic agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
DE3163018D1 (en) * 1980-02-02 1984-05-17 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
FR2476644A1 (fr) * 1980-02-21 1981-08-28 Sarget Lab Orthoarylydeneaminophenethylamine, leur preparation et leur utilisation therapeutique
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
SU1068439A1 (ru) * 1982-10-28 1984-01-23 Новокузнецкий научно-исследовательский химико-фармацевтический институт Производные имидазо(4,5- @ ) индолов
US4579865A (en) * 1983-02-14 1986-04-01 Usv Pharmaceutical Corp. Benzofuranyl carbamates
US4548943A (en) * 1984-05-11 1985-10-22 E. I. Du Pont De Nemours And Company Antiinflammatory, analgesic, or anti-primary dysmenorrheal arylmethylene- and arylmethylindenoimidazoles
PL147842B1 (en) * 1984-05-12 1989-08-31 Method of obtaining novel pyroisobenzimidazoles
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS61158984A (ja) 1986-07-18
CS276403B6 (en) 1992-05-13
HU194241B (en) 1988-01-28
ES549776A0 (es) 1987-01-16
ATE49970T1 (de) 1990-02-15
ES8702409A1 (es) 1987-01-16
CS919585A3 (en) 1992-01-15
JPH0471914B2 (da) 1992-11-16
DE3445669A1 (de) 1986-06-19
US4710510A (en) 1987-12-01
DE3575725D1 (de) 1990-03-08
ZA859382B (en) 1986-08-27
CA1262908A (en) 1989-11-14
FI79318B (fi) 1989-08-31
HUT40436A (en) 1986-12-28
AU5100685A (en) 1986-06-19
DD242045A5 (de) 1987-01-14
AU580822B2 (en) 1989-02-02
EP0186010A1 (de) 1986-07-02
FI79318C (fi) 1989-12-11
EP0186010B1 (de) 1990-01-31
GR852979B (da) 1986-04-08
FI854926A0 (fi) 1985-12-12
SU1440348A3 (ru) 1988-11-23
DK579185A (da) 1986-06-15
FI854926A (fi) 1986-06-15
US4810801A (en) 1989-03-07

Similar Documents

Publication Publication Date Title
DE3266464D1 (en) Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith
DK579185A (da) Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf
HK121293A (en) Desulfatohirudine,process for its preparation and pharmaceutical agent
PT76495A (en) Process for preparing new imidazolphenyl-tetrahydropyridazines
JPS57122085A (en) Circulatory disease extirpenter and use
EP0214592A3 (en) Pyrrolobenzimidazoles, pyrrolobenzoxazoles and pyrrolobenzothiazoles, process for their preparation and medicaments containing these products
ES8306994A1 (es) Procedimiento para la obtencion de diamidas de acido hidroxi-maloico sustituidas.
ZA875640B (en) 2-acyloxypropylamine derivatives,process for the preparation thereof and pharmaceutical compositions containing them
HUT46214A (en) Process for producing medical preparation suitable for treatment of peptic ulcer
ATE2429T1 (de) 6-imidazol-1-yl-3-hydrazino-pyridazine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ZA814902B (en) Novel thiazol-2-yl-oxamic acid derivatives,their preparation and therapeutic agents containing these compounds
ZA885335B (en) Leukotriene antagonists,processes for the preparation thereof,the use thereof for the treatment of diseases,and precursors
IL87198A (en) Leukotriene antagonists,a process for the preparation thereof and pharmaceutical compositions containing them
NO851145L (no) N-bicykloheptyl- og n-bicykloheptenyl-imidazoler, fremgangsmaate til deres fremstilling, deres anvendelse samt farmasoeytiske preparater

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment