DK579185A - Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf - Google Patents

Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf Download PDF

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Publication number
DK579185A
DK579185A DK579185A DK579185A DK579185A DK 579185 A DK579185 A DK 579185A DK 579185 A DK579185 A DK 579185A DK 579185 A DK579185 A DK 579185A DK 579185 A DK579185 A DK 579185A
Authority
DK
Denmark
Prior art keywords
pyrrolobenzimidazoles
medicines
preparing
contents
present
Prior art date
Application number
DK579185A
Other languages
English (en)
Other versions
DK579185D0 (da
Inventor
Alfred Mertens
Jens-Peter Hoelck
Wolfgang Kampe
Bernd Mueller-Beckmann
Klaus Strein
Wolfgang Schaumann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK579185D0 publication Critical patent/DK579185D0/da
Publication of DK579185A publication Critical patent/DK579185A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
DK579185A 1984-12-14 1985-12-13 Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf DK579185A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445669 DE3445669A1 (de) 1984-12-14 1984-12-14 Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK579185D0 DK579185D0 (da) 1985-12-13
DK579185A true DK579185A (da) 1986-06-15

Family

ID=6252801

Family Applications (1)

Application Number Title Priority Date Filing Date
DK579185A DK579185A (da) 1984-12-14 1985-12-13 Pyrrolobenzimidazoler, fremgangsmaade til fremstilling heraf samt laegemidler med indhold heraf

Country Status (16)

Country Link
US (2) US4710510A (da)
EP (1) EP0186010B1 (da)
JP (1) JPS61158984A (da)
AT (1) ATE49970T1 (da)
AU (1) AU580822B2 (da)
CA (1) CA1262908A (da)
CS (1) CS276403B6 (da)
DD (1) DD242045A5 (da)
DE (2) DE3445669A1 (da)
DK (1) DK579185A (da)
ES (1) ES8702409A1 (da)
FI (1) FI79318C (da)
GR (1) GR852979B (da)
HU (1) HU194241B (da)
SU (1) SU1440348A3 (da)
ZA (1) ZA859382B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3626664A1 (de) * 1986-08-07 1988-02-11 Boehringer Mannheim Gmbh Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3639466A1 (de) * 1986-11-18 1988-05-19 Thomae Gmbh Dr K Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3642315A1 (de) * 1986-12-11 1988-06-23 Boehringer Mannheim Gmbh Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3701277A1 (de) * 1987-01-17 1988-07-28 Boehringer Mannheim Gmbh Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3740985A1 (de) * 1987-12-03 1989-06-15 Boehringer Mannheim Gmbh Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation
ATE138658T1 (de) * 1987-12-30 1996-06-15 Orion Yhtymae Oy Heterocyclische verbindungen
US4963677A (en) * 1987-12-30 1990-10-16 Orion Corporation Ltd. Heterocyclic lactam compounds
DE3803775A1 (de) * 1988-02-09 1989-08-17 Boehringer Mannheim Gmbh Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US7186745B2 (en) * 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
WO2002072549A1 (en) * 2001-03-12 2002-09-19 Millennium Pharmaceuticals, Inc. Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
JP2007518816A (ja) * 2004-01-23 2007-07-12 アムジエン・インコーポレーテツド バニロイド受容体リガンド及び炎症性及び神経因性疼痛の治療におけるこれらの使用
AU2013314417B2 (en) 2012-09-13 2016-01-21 F. Hoffmann-La Roche Ag 2-oxo-2,3-dihydro-indoles for the treatment of CNS disorders
DK3174868T3 (da) 2014-08-01 2021-11-08 Nuevolution As Forbindelser, der er aktive mod bromodomæner
GB201709456D0 (en) 2017-06-14 2017-07-26 Ucb Biopharma Sprl Therapeutic agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
EP0033612B1 (en) * 1980-02-02 1984-04-11 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
FR2476644A1 (fr) * 1980-02-21 1981-08-28 Sarget Lab Orthoarylydeneaminophenethylamine, leur preparation et leur utilisation therapeutique
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
SU1068439A1 (ru) * 1982-10-28 1984-01-23 Новокузнецкий научно-исследовательский химико-фармацевтический институт Производные имидазо(4,5- @ ) индолов
US4579865A (en) * 1983-02-14 1986-04-01 Usv Pharmaceutical Corp. Benzofuranyl carbamates
US4548943A (en) * 1984-05-11 1985-10-22 E. I. Du Pont De Nemours And Company Antiinflammatory, analgesic, or anti-primary dysmenorrheal arylmethylene- and arylmethylindenoimidazoles
PL144822B1 (en) * 1984-05-12 1988-07-30 Boehringer Mannheim Gmbh Method of obtaining novel pyrolobenzimidazoles
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
CA1262908A (en) 1989-11-14
US4810801A (en) 1989-03-07
ZA859382B (en) 1986-08-27
ES549776A0 (es) 1987-01-16
DD242045A5 (de) 1987-01-14
ES8702409A1 (es) 1987-01-16
CS276403B6 (en) 1992-05-13
FI854926A0 (fi) 1985-12-12
FI854926A (fi) 1986-06-15
FI79318B (fi) 1989-08-31
EP0186010A1 (de) 1986-07-02
AU580822B2 (en) 1989-02-02
HUT40436A (en) 1986-12-28
FI79318C (fi) 1989-12-11
SU1440348A3 (ru) 1988-11-23
EP0186010B1 (de) 1990-01-31
AU5100685A (en) 1986-06-19
JPH0471914B2 (da) 1992-11-16
HU194241B (en) 1988-01-28
DE3445669A1 (de) 1986-06-19
US4710510A (en) 1987-12-01
ATE49970T1 (de) 1990-02-15
CS919585A3 (en) 1992-01-15
GR852979B (da) 1986-04-08
DE3575725D1 (de) 1990-03-08
DK579185D0 (da) 1985-12-13
JPS61158984A (ja) 1986-07-18

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AHS Application shelved for other reasons than non-payment