ES8104307A1 - Procedimiento para la preparacion de derivados heterocicli- cos de cefalosporinas oxi-imino-substituidas - Google Patents

Procedimiento para la preparacion de derivados heterocicli- cos de cefalosporinas oxi-imino-substituidas

Info

Publication number
ES8104307A1
ES8104307A1 ES491379A ES491379A ES8104307A1 ES 8104307 A1 ES8104307 A1 ES 8104307A1 ES 491379 A ES491379 A ES 491379A ES 491379 A ES491379 A ES 491379A ES 8104307 A1 ES8104307 A1 ES 8104307A1
Authority
ES
Spain
Prior art keywords
amino
tetrazolo
cephem
methoxyimino
thiomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491379A
Other languages
English (en)
Other versions
ES491379A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of ES8104307A1 publication Critical patent/ES8104307A1/es
Publication of ES491379A0 publication Critical patent/ES491379A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • C07C59/21—Saturated compounds having only one carboxyl group and containing keto groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS HETEROCICLOS DE CEFALOSPORINAS OXIIMINO-SUSTITUIDAS, DE FORMULA GENERAL (I), Y SUS SALES ACEPTABLES FARMACEUTICAMENTE Y EN VETERINARIA, DONDE R, R1 Y R2 SON DISTINTOS TIPOS DE ATOMOS DE RADICALES; X ES 0, 1 O 2. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), DONDE E REPRESENTA UN GRUPO AMINICO O UN GRUPO RADICAL, CON UN COMPUESTO DE FORMULA (III). TAMBIEN SE REIVINDICAN OTROS TIPOS DE REACCIONES. ESTOS COMPUESTOS TIENEN APLICACIONES ANTIBACTERIANAS. *FORMULA*
ES491379A 1979-05-11 1980-05-10 Procedimiento para la preparacion de derivados heterocicli- cos de cefalosporinas oxi-imino-substituidas Granted ES491379A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7916376 1979-05-11

Publications (2)

Publication Number Publication Date
ES8104307A1 true ES8104307A1 (es) 1981-04-01
ES491379A0 ES491379A0 (es) 1981-04-01

Family

ID=10505086

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491379A Granted ES491379A0 (es) 1979-05-11 1980-05-10 Procedimiento para la preparacion de derivados heterocicli- cos de cefalosporinas oxi-imino-substituidas

Country Status (25)

Country Link
US (1) US4331666A (es)
JP (1) JPS55151594A (es)
AT (1) AT368512B (es)
AU (1) AU530638B2 (es)
BE (1) BE883209A (es)
CA (1) CA1148939A (es)
CS (1) CS219277B2 (es)
DE (1) DE3015389A1 (es)
DK (1) DK191080A (es)
ES (1) ES491379A0 (es)
FI (1) FI801517A (es)
FR (1) FR2456109A1 (es)
GB (1) GB2053896B (es)
GR (1) GR67280B (es)
IL (1) IL59791A0 (es)
IT (1) IT1195268B (es)
LU (1) LU82429A1 (es)
NL (1) NL8002690A (es)
NO (1) NO801400L (es)
NZ (1) NZ193615A (es)
PH (1) PH17085A (es)
PT (1) PT71220A (es)
SE (1) SE8003429L (es)
SU (1) SU1005664A3 (es)
ZA (1) ZA802393B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4499088A (en) * 1983-01-04 1985-02-12 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
EP0359291A1 (en) * 1985-04-01 1990-03-21 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
AU586229B2 (en) * 1985-04-01 1989-07-06 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
EP0225634B1 (en) * 1985-12-13 1994-04-06 Takeda Chemical Industries, Ltd. Antibacterial compounds, their production and use
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
GB8805642D0 (en) * 1988-03-09 1988-04-07 Fujisawa Pharmaceutical Co New cephem compounds & processes for preparation thereof
EP0333082A3 (en) * 1988-03-15 1991-05-02 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
WO2023250017A1 (en) * 2022-06-21 2023-12-28 Ohio State Innovation Foundation Compounds for treating infections

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
US4061861A (en) * 1976-06-21 1977-12-06 Eli Lilly And Company 7-[α-(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino)arylacetamido]cephalosporins
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
JPS5511600A (en) * 1978-07-10 1980-01-26 Fujisawa Pharmaceut Co Ltd Cephem compound, its salt, their preparation and remedy and prophylactic for microbism containing mainly the same
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof

Also Published As

Publication number Publication date
SE8003429L (sv) 1980-11-12
FI801517A (fi) 1980-11-12
FR2456109A1 (fr) 1980-12-05
CA1148939A (en) 1983-06-28
IL59791A0 (en) 1980-06-30
JPS55151594A (en) 1980-11-26
CS219277B2 (en) 1983-03-25
GR67280B (es) 1981-06-26
NO801400L (no) 1980-11-12
AU5744080A (en) 1980-11-13
DK191080A (da) 1980-11-12
AU530638B2 (en) 1983-07-21
ZA802393B (en) 1981-04-29
US4331666A (en) 1982-05-25
GB2053896A (en) 1981-02-11
FR2456109B1 (es) 1983-12-16
BE883209A (fr) 1980-11-10
IT1195268B (it) 1988-10-12
DE3015389A1 (de) 1980-11-20
IT8021822A0 (it) 1980-05-06
SU1005664A3 (ru) 1983-03-15
ES491379A0 (es) 1981-04-01
PT71220A (en) 1980-06-01
NZ193615A (en) 1982-02-23
LU82429A1 (fr) 1980-07-31
AT368512B (de) 1982-10-25
NL8002690A (nl) 1980-11-13
GB2053896B (en) 1983-04-07
ATA249680A (de) 1982-02-15
PH17085A (en) 1984-05-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201