ES8102559A1 - Un procedimiento para la preparacion de la forma racemica y de las formas esteroisomeras de ellas de un derivado del a- cido 1,2,3,4-tetrahidro-2-quinolincarboxilico - Google Patents
Un procedimiento para la preparacion de la forma racemica y de las formas esteroisomeras de ellas de un derivado del a- cido 1,2,3,4-tetrahidro-2-quinolincarboxilicoInfo
- Publication number
- ES8102559A1 ES8102559A1 ES488313A ES488313A ES8102559A1 ES 8102559 A1 ES8102559 A1 ES 8102559A1 ES 488313 A ES488313 A ES 488313A ES 488313 A ES488313 A ES 488313A ES 8102559 A1 ES8102559 A1 ES 8102559A1
- Authority
- ES
- Spain
- Prior art keywords
- acylthio
- oxoalkyl
- tetrahydroquinoline
- mercapto
- carboxylic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000005035 acylthio group Chemical group 0.000 title abstract 2
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1016579A | 1979-02-07 | 1979-02-07 | |
| US06/090,862 US4461896A (en) | 1979-02-07 | 1979-11-02 | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES488313A0 ES488313A0 (es) | 1981-01-16 |
| ES8102559A1 true ES8102559A1 (es) | 1981-01-16 |
Family
ID=26680853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES488313A Expired ES8102559A1 (es) | 1979-02-07 | 1980-02-06 | Un procedimiento para la preparacion de la forma racemica y de las formas esteroisomeras de ellas de un derivado del a- cido 1,2,3,4-tetrahidro-2-quinolincarboxilico |
Country Status (16)
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2937779A1 (de) * | 1979-09-19 | 1981-04-09 | Hoechst Ag, 6000 Frankfurt | Aminosaeurederivate und verfahren zu ihrer herstellung |
| US4595675A (en) * | 1979-09-19 | 1986-06-17 | Hoechst Aktiengesellschaft | Bicyclic α-iminocarboxylic acid compounds having hypotensive activity |
| DE3044236A1 (de) * | 1980-11-25 | 1982-06-16 | Hoechst Ag, 6000 Frankfurt | Aminosaeurederivate und verfahren zu ihrer herstellung |
| FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
| FR2487829A2 (fr) * | 1979-12-07 | 1982-02-05 | Science Union & Cie | Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
| US4599357A (en) * | 1979-12-17 | 1986-07-08 | Ciba-Geigy Corporation | 1-mercaptoalkanoylindoline-2-carboxylic acids |
| US4350704A (en) | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
| IE52663B1 (en) * | 1980-04-02 | 1988-01-20 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids |
| DE3177311D1 (de) * | 1980-08-30 | 1994-06-09 | Hoechst Ag | Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung. |
| US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| US4390700A (en) | 1980-11-10 | 1983-06-28 | Ciba-Geigy Corporation | 1-Carboxyazaalkanoyl-tetrahydroquinoline-2-carboxylic acids |
| US4401818A (en) | 1980-12-24 | 1983-08-30 | Ciba-Geigy Corporation | 1-Carboxyalkanoyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acids |
| EP0058567B1 (en) * | 1981-02-17 | 1984-07-25 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters |
| US4532342A (en) * | 1981-02-20 | 1985-07-30 | Warner-Lambert Company | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| US4374246A (en) * | 1981-06-18 | 1983-02-15 | Norwich Eaton Pharmaceuticals, Inc. | 1-N-[(1-Carboxy-3-phenylpropyl)glycyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds |
| US5025001A (en) * | 1988-06-15 | 1991-06-18 | Brigham And Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
| US5187183A (en) * | 1988-06-15 | 1993-02-16 | Brigham & Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
| US5356890A (en) * | 1988-06-15 | 1994-10-18 | Brigham And Women's Hospital | S-nitroso derivatives of ace inhibitors and the use thereof |
| GB9010394D0 (en) * | 1990-05-09 | 1990-06-27 | Ici Plc | Heterocyclic compounds |
| US5504080A (en) * | 1992-10-28 | 1996-04-02 | Bristol-Myers Squibb Co. | Benzo-fused lactams |
| EP0706525A1 (en) * | 1993-06-30 | 1996-04-17 | Novartis AG | Antihypertensive tricyclic azepine derivatives useful as inhibitors of enkephalinase and ace |
| ITMI20012060A1 (it) * | 2001-10-05 | 2003-04-05 | Recordati Chem Pharm | Nuovi eterocilcli n-acilati |
| US8916550B2 (en) * | 2005-05-09 | 2014-12-23 | Hydra Biosciences, Inc. | Compounds for modulating TRPV3 function |
| TWI401254B (zh) * | 2005-05-09 | 2013-07-11 | Hydra Biosciences Inc | 用於調節ｔｒｐｖ３功能之化合物 |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| WO2008033564A1 (en) * | 2006-09-15 | 2008-03-20 | Hydra Biosciences Inc. | Compounds for modulating trpv3 function |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| EP3714932A1 (en) | 2011-07-12 | 2020-09-30 | ICU Medical, Inc. | Device for delivery of antimicrobial agent into a transdermal catheter |
| WO2015168677A1 (en) | 2014-05-02 | 2015-11-05 | Excelsior Medical Corporation | Strip package for antiseptic cap |
| CA2982456A1 (en) | 2015-05-08 | 2016-11-17 | Icu Medical, Inc. | Medical connectors configured to receive emitters of therapeutic agents |
| DK3525865T3 (da) | 2016-10-14 | 2022-10-24 | Icu Medical Inc | Desinficerende hætter til medicinsk konnektorer |
| WO2018204206A2 (en) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Medical fluid connectors and methods for providing additives in medical fluid lines |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| CA3118905A1 (en) | 2018-11-21 | 2020-05-28 | Icu Medical, Inc. | Antimicrobial device comprising a cap with ring and insert |
| JP2023512664A (ja) | 2020-01-29 | 2023-03-28 | カマリ ファーマ リミテッド | 皮膚障害の治療に使用するための化合物及び組成物 |
| WO2022125474A1 (en) | 2020-12-07 | 2022-06-16 | Icu Medical, Inc. | Peritoneal dialysis caps, systems and methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR837847A (fr) * | 1937-05-13 | 1939-02-21 | Ste Ind Chim Bale | Agents auxiliaires pour l'impression |
| US4104392A (en) * | 1974-11-08 | 1978-08-01 | Mitsubishi Chemical Industries Ltd. | N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them |
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| AU4091178A (en) * | 1977-10-25 | 1980-04-24 | Merck & Co Inc | Substituted mercapto acid amides |
-
1979
- 1979-11-02 US US06/090,862 patent/US4461896A/en not_active Expired - Lifetime
-
1980
- 1980-01-04 IE IE14/80A patent/IE49350B1/en unknown
- 1980-01-07 IL IL59089A patent/IL59089A/xx unknown
- 1980-01-10 SE SE8000209A patent/SE436031B/sv not_active IP Right Cessation
- 1980-01-14 GR GR60950A patent/GR74103B/el unknown
- 1980-01-15 NZ NZ192613A patent/NZ192613A/xx unknown
- 1980-01-18 AU AU54727/80A patent/AU527887B2/en not_active Ceased
- 1980-01-28 IT IT47730/80A patent/IT1145330B/it active
- 1980-01-31 NL NL8000641A patent/NL8000641A/nl not_active Application Discontinuation
- 1980-02-05 GB GB8003806A patent/GB2042535B/en not_active Expired
- 1980-02-06 DE DE19803004370 patent/DE3004370A1/de active Granted
- 1980-02-06 DK DK051280A patent/DK152209C/da not_active IP Right Cessation
- 1980-02-06 CH CH96180A patent/CH645355A5/de not_active IP Right Cessation
- 1980-02-06 ES ES488313A patent/ES8102559A1/es not_active Expired
- 1980-02-06 PT PT70793A patent/PT70793A/pt unknown
- 1980-02-06 FR FR8002592A patent/FR2448533A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU5472780A (en) | 1980-08-14 |
| CH645355A5 (de) | 1984-09-28 |
| IL59089A0 (en) | 1980-05-30 |
| IT1145330B (it) | 1986-11-05 |
| GB2042535A (en) | 1980-09-24 |
| US4461896A (en) | 1984-07-24 |
| AU527887B2 (en) | 1983-03-31 |
| IT8047730A0 (it) | 1980-01-28 |
| IE800014L (en) | 1980-08-07 |
| DE3004370C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-10-26 |
| IE49350B1 (en) | 1985-09-18 |
| FR2448533B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1983-01-07 |
| FR2448533A1 (fr) | 1980-09-05 |
| GR74103B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-06-06 |
| GB2042535B (en) | 1983-01-26 |
| DK152209C (da) | 1988-06-20 |
| DE3004370A1 (de) | 1980-08-14 |
| ES488313A0 (es) | 1981-01-16 |
| IL59089A (en) | 1982-08-31 |
| PT70793A (en) | 1980-03-01 |
| DK152209B (da) | 1988-02-08 |
| DK51280A (da) | 1980-08-08 |
| SE8000209L (sv) | 1980-08-08 |
| NZ192613A (en) | 1981-10-19 |
| NL8000641A (nl) | 1980-08-11 |
| SE436031B (sv) | 1984-11-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8102559A1 (es) | Un procedimiento para la preparacion de la forma racemica y de las formas esteroisomeras de ellas de un derivado del a- cido 1,2,3,4-tetrahidro-2-quinolincarboxilico | |
| MY106606A (en) | Cycloalkyl-substituted glutaramide antihypertensive agents. | |
| DE3681465D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| ES8307263A1 (es) | Un procedimiento para la preparacion de fosfonamidas sustituidas. | |
| DE3277302D1 (en) | Phosphorus containing compounds | |
| IE810474L (en) | Anti-hypertensive agents | |
| ATE12502T1 (de) | Phosphinylalkanoyl-substituierte proline. | |
| GB2116559B (en) | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors | |
| NZ194002A (en) | Angiotensin converting enzyme inhibitors and anti-hypertensive compositions | |
| JPS5589230A (en) | Angiotensin conversion enzyme inhibitor | |
| ES482598A1 (es) | Un procedimiento para la preparacion de n-(diaminofosfinil) aril-carboxamidas. | |
| ES8204421A1 (es) | Un procedimiento para la preparacion de nuevos derivados del acido 1-(ciclohexil)-4-aril--4-piperidincarboxilico. | |
| AU7309981A (en) | Amide derivatives which inhibit angiotensin converting enzyme | |
| BG34463A3 (bg) | Метод за получаване на инхибитор на превръщащия ангиотенизина ензим | |
| ES460204A1 (es) | Un procedimiento para la preparacion de acidos ureido(susti-tuidos) acetohidroxamicos. | |
| BG35898A3 (en) | Method for preparing 1- (4- aryl- cyclohexyl)- piperidines | |
| ZA88498B (en) | Alkylmelatonins | |
| ZA806786B (en) | 4-substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | |
| ES8800352A1 (es) | Un procedimiento para producir un compuesto capaz de funcionar como una elastasa pancreatica humana | |
| ES8205126A1 (es) | Un procedimiento para la preparacion de un inhibidor del enzima convertidor de la angiotensina. | |
| AU7409487A (en) | Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors | |
| GR862285B (en) | Pharmaceutical compositions for treating the high blood pressure | |
| ES8205218A1 (es) | Un procedimiento para la preparacion de pirrolilpiperidinas utiles como agentes antidepresivo. | |
| SU1220180A1 (ru) | Установка для массообмена | |
| BG41127A3 (en) | Method for preparing 1, 4- dihydropyridine derivatives |