ES545888A0 - Un metodo para producir compuestos de 2'-desoxiadenosina - Google Patents

Un metodo para producir compuestos de 2'-desoxiadenosina

Info

Publication number
ES545888A0
ES545888A0 ES545888A ES545888A ES545888A0 ES 545888 A0 ES545888 A0 ES 545888A0 ES 545888 A ES545888 A ES 545888A ES 545888 A ES545888 A ES 545888A ES 545888 A0 ES545888 A0 ES 545888A0
Authority
ES
Spain
Prior art keywords
deoxyadenosine
producing
compounds
deoxyadenosine compounds
dichloropurine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES545888A
Other languages
English (en)
Other versions
ES8606383A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of ES545888A0 publication Critical patent/ES545888A0/es
Publication of ES8606383A1 publication Critical patent/ES8606383A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES545888A 1984-08-06 1985-08-05 Un metodo para producir compuestos de 2'-desoxiadenosina Expired ES8606383A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63819284A 1984-08-06 1984-08-06

Publications (2)

Publication Number Publication Date
ES545888A0 true ES545888A0 (es) 1986-04-01
ES8606383A1 ES8606383A1 (es) 1986-04-01

Family

ID=24559020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545888A Expired ES8606383A1 (es) 1984-08-06 1985-08-05 Un metodo para producir compuestos de 2'-desoxiadenosina

Country Status (9)

Country Link
EP (1) EP0173059B1 (es)
JP (2) JPS61106594A (es)
AT (1) ATE48278T1 (es)
AU (1) AU572673B2 (es)
CA (1) CA1269659A (es)
DE (1) DE3574472D1 (es)
DK (1) DK165453C (es)
ES (1) ES8606383A1 (es)
ZA (1) ZA855696B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0217199A (ja) * 1988-07-05 1990-01-22 Japan Tobacco Inc ２’−デオキシ−β−アデノシンの製造方法
JPH02160799A (ja) * 1988-12-13 1990-06-20 Yuki Gosei Kogyo Co Ltd ２′−デオキシ−β−アデノシンの製造法
US5208327A (en) 1991-12-18 1993-05-04 Ortho Pharmaceutical Corporation Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
AU2003275267A1 (en) * 2002-09-25 2004-04-19 Brigham Young University, Technology Transfer Office Method for the preparation of 2-halo-2'-deoxyadenosine compounds from 2'-deoxyguanosine
EP1827461B1 (en) 2004-12-22 2012-02-29 Merck Serono SA Cladribine regimen for treating multiple sclerosis
JP2009537605A (ja) 2006-05-24 2009-10-29 メルク セローノ ソシエテ アノニム 多発性硬化症を治療するためのクラドリビン・レジメン
PL1932918T3 (pl) 2006-12-15 2010-03-31 Explora Laboratories Sa Sposób otrzymywania kladrybiny
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
MX2011006891A (es) 2008-12-23 2011-10-06 Pharmasset Inc Fosforamidatos de nucleosidos.
NZ593647A (en) 2008-12-23 2013-08-30 Gilead Pharmasset Llc Synthesis of purine nucleosides
EP2376514A2 (en) 2008-12-23 2011-10-19 Pharmasset, Inc. Nucleoside analogs
TWI399381B (zh) 2009-08-18 2013-06-21 Scinopharm Taiwan Ltd 克拉屈濱（ｃｌａｄｒｉｂｉｎｅ）的製備方法
EP2343074A1 (en) 2009-12-23 2011-07-13 Merck Serono S.A. Use of purine analogues for treating airway diseases
WO2011113476A2 (en) 2010-03-16 2011-09-22 Cilag Ag Method for producing 2'-deoxyadenosine compounds
AU2011235112B2 (en) 2010-03-31 2015-07-09 Gilead Pharmasset Llc Nucleoside phosphoramidates
GB201401465D0 (en) 2014-01-29 2014-03-12 Roach Arthur H Use of cladribine for treating autoimmune inflammatory disease
EP2993177A1 (en) 2014-09-05 2016-03-09 Technische Universität Berlin A chemo-enzymatic preparation method for purine nucleosides and their deaza- and aza- analogues
GB2564717A (en) 2017-07-21 2019-01-23 Chord Therapeutics S A R L Use of cladribine for treating autoimmune neuromuscular disease
MX2020005266A (es) 2017-11-24 2020-09-18 Merck Patent Gmbh Regimen de cladribina para usarse en el tratamiento de formas progresivas de esclerosis multiple.
BR112023003432A2 (pt) 2020-09-10 2023-03-21 Merck Patent Gmbh Regime de tratamento para o tratamento de doenças autoimunes
GB2601786A (en) 2020-12-10 2022-06-15 Chord Therapeutics S A R L Use of cladribine for treating immune brain disease
EP4302091A1 (en) 2021-03-03 2024-01-10 Ares Trading S.A. Improved treatment methods using dmds for the treatment of autoimmune diseases, and biomarker for predicting and/or optimising said treatment methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3225029A (en) * 1962-03-08 1965-12-21 Yamaoka Naotaka Process for the preparation of nucleosides and products obtained thereby
US3225008A (en) * 1962-05-21 1965-12-21 Scott Paper Co Itaconic esters of 1,2 alkane carbonates, polymers, and copolymers thereof
DE1795357A1 (de) * 1968-09-18 1972-01-05 Schering Ag 2-Thio-pyrimidin-nucleoside
DE3587500T2 (de) * 1984-12-04 1993-12-16 Lilly Co Eli Tumorbehandlung bei Säugetieren.

Also Published As

Publication number Publication date
CA1269659A (en) 1990-05-29
AU4513885A (en) 1986-02-13
DK357585A (da) 1986-02-07
ZA855696B (en) 1986-04-30
JPH0256497A (ja) 1990-02-26
AU572673B2 (en) 1988-05-12
ES8606383A1 (es) 1986-04-01
EP0173059A3 (en) 1987-04-29
EP0173059A2 (en) 1986-03-05
DK165453B (da) 1992-11-30
EP0173059B1 (en) 1989-11-29
ATE48278T1 (de) 1989-12-15
JPH02359B2 (es) 1990-01-08
DE3574472D1 (de) 1990-01-04
DK165453C (da) 1993-04-13
DK357585D0 (da) 1985-08-06
JPS61106594A (ja) 1986-05-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051029