ES542447A0 - "un procedimiento para preparar un derivado de cefem". - Google Patents
"un procedimiento para preparar un derivado de cefem".Info
- Publication number
- ES542447A0 ES542447A0 ES542447A ES542447A ES542447A0 ES 542447 A0 ES542447 A0 ES 542447A0 ES 542447 A ES542447 A ES 542447A ES 542447 A ES542447 A ES 542447A ES 542447 A0 ES542447 A0 ES 542447A0
- Authority
- ES
- Spain
- Prior art keywords
- cefem
- derivative
- prepare
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP1984/000212 WO1985004879A1 (fr) | 1984-04-23 | 1984-04-23 | Nouveaux composes de cephem |
| PCT/JP1984/000270 WO1985005620A1 (en) | 1984-05-25 | 1984-05-25 | Cephem compounds |
| PCT/JP1985/000102 WO1986005184A1 (en) | 1985-03-01 | 1985-03-01 | Antibacterial compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES542447A0 true ES542447A0 (es) | 1986-04-01 |
| ES8606362A1 ES8606362A1 (es) | 1986-04-01 |
Family
ID=27304399
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542447A Expired ES8606362A1 (es) | 1984-04-23 | 1985-04-22 | "un procedimiento para preparar un derivado de cefem". |
| ES549180A Expired ES8707245A1 (es) | 1984-04-23 | 1985-11-22 | Un metodo para preparar nuevos derivados de cefem |
| ES553666A Expired ES8706692A1 (es) | 1984-04-23 | 1986-04-03 | Un metodo para preparar nuevos derivados de cefem |
| ES557129A Expired ES8800950A1 (es) | 1984-04-23 | 1986-10-03 | Un metodo para preparar nuevos derivados de cefem |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES549180A Expired ES8707245A1 (es) | 1984-04-23 | 1985-11-22 | Un metodo para preparar nuevos derivados de cefem |
| ES553666A Expired ES8706692A1 (es) | 1984-04-23 | 1986-04-03 | Un metodo para preparar nuevos derivados de cefem |
| ES557129A Expired ES8800950A1 (es) | 1984-04-23 | 1986-10-03 | Un metodo para preparar nuevos derivados de cefem |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0160252B1 (es) |
| JP (1) | JPH07103130B2 (es) |
| KR (2) | KR920008945B1 (es) |
| AU (1) | AU580995B2 (es) |
| CA (1) | CA1283096C (es) |
| DE (2) | DE3586547T2 (es) |
| ES (4) | ES8606362A1 (es) |
| FI (1) | FI851592L (es) |
| GR (1) | GR850965B (es) |
| NO (2) | NO165842C (es) |
| NZ (1) | NZ211858A (es) |
| PH (1) | PH23134A (es) |
| PT (1) | PT80328B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH22107A (en) * | 1984-06-07 | 1988-06-01 | Takeda Chemical Industries Ltd | 3-pyrazolo(1,5-a)pyrdinium cephem compounds |
| NO166283C (no) * | 1985-03-01 | 1991-06-26 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(5-amino-1,2,4-tiadiazol-3-yl)-2(z)-substituertoksyiminoacetamido)-3-(heterocyclylmetyl)-3-cefem-4-karboksylsyrederivater. |
| ATE89826T1 (de) * | 1985-03-01 | 1993-06-15 | Takeda Chemical Industries Ltd | Antibakterielle verbindungen, ihre herstellung und verwendung. |
| US4921851A (en) * | 1986-06-09 | 1990-05-01 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
| JP2519054B2 (ja) * | 1986-06-09 | 1996-07-31 | 武田薬品工業株式会社 | 新規セフェム化合物 |
| DE3707019A1 (de) * | 1987-03-05 | 1988-09-15 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| AU615966B2 (en) * | 1987-12-04 | 1991-10-17 | Takeda Chemical Industries Ltd. | Crystals of cephem hydrochloride |
| US4933334A (en) * | 1987-12-04 | 1990-06-12 | Takeda Chemical Industries, Ltd. | Antibiotic composition |
| DE69106902T2 (de) * | 1990-03-01 | 1995-07-06 | Takeda Chemical Industries Ltd | Imidazopyridazine, ihre Herstellung und Verwendung. |
| TW526202B (en) | 1998-11-27 | 2003-04-01 | Shionogi & Amp Co | Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity |
| ATE449775T1 (de) * | 2003-04-30 | 2009-12-15 | Trine Pharmaceuticals Inc | Carbacephem beta-lactam-antibiotika |
| RS55365B1 (sr) | 2008-10-31 | 2017-03-31 | Shionogi & Co | Cefalosporin sa kateholskom grupom |
| IN2012CN09242A (es) | 2010-04-05 | 2015-08-21 | Shionogi & Co | |
| TWI547496B (zh) | 2011-10-04 | 2016-09-01 | 葛蘭素集團公司 | 抗菌化合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165430A (en) * | 1976-03-19 | 1979-08-21 | Glaxo Laboratories Limited | Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group |
| DE3279470D1 (en) * | 1981-04-03 | 1989-04-06 | Fujisawa Pharmaceutical Co | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
| DE3336757A1 (de) * | 1983-10-08 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
-
1985
- 1985-04-17 NO NO851538A patent/NO165842C/no unknown
- 1985-04-18 PH PH32153A patent/PH23134A/en unknown
- 1985-04-18 DE DE8585104687T patent/DE3586547T2/de not_active Expired - Lifetime
- 1985-04-18 DE DE8585104687A patent/DE3586547D1/de not_active Expired - Fee Related
- 1985-04-18 EP EP85104687A patent/EP0160252B1/en not_active Expired - Lifetime
- 1985-04-22 JP JP60086746A patent/JPH07103130B2/ja not_active Expired - Fee Related
- 1985-04-22 NZ NZ211858A patent/NZ211858A/xx unknown
- 1985-04-22 GR GR850965A patent/GR850965B/el unknown
- 1985-04-22 FI FI851592A patent/FI851592L/fi not_active Application Discontinuation
- 1985-04-22 ES ES542447A patent/ES8606362A1/es not_active Expired
- 1985-04-22 PT PT80328A patent/PT80328B/pt not_active IP Right Cessation
- 1985-04-23 CA CA000479769A patent/CA1283096C/en not_active Expired - Lifetime
- 1985-04-23 AU AU41700/85A patent/AU580995B2/en not_active Ceased
- 1985-04-23 KR KR1019850002737A patent/KR920008945B1/ko not_active IP Right Cessation
- 1985-11-22 ES ES549180A patent/ES8707245A1/es not_active Expired
- 1985-11-26 NO NO85854730A patent/NO167293C/no unknown
-
1986
- 1986-04-03 ES ES553666A patent/ES8706692A1/es not_active Expired
- 1986-10-03 ES ES557129A patent/ES8800950A1/es not_active Expired
-
1991
- 1991-11-16 KR KR1019910020376A patent/KR920008953B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO167293B (no) | 1991-07-15 |
| KR920008953B1 (ko) | 1992-10-12 |
| CA1283096C (en) | 1991-04-16 |
| EP0160252A2 (en) | 1985-11-06 |
| NO165842C (no) | 1991-04-17 |
| JPS60231684A (ja) | 1985-11-18 |
| KR850007427A (ko) | 1985-12-04 |
| FI851592L (fi) | 1985-10-24 |
| ES8800950A1 (es) | 1987-12-01 |
| NO854730L (no) | 1985-10-24 |
| ES8706692A1 (es) | 1987-06-16 |
| KR920008945B1 (ko) | 1992-10-12 |
| NO165842B (no) | 1991-01-07 |
| GR850965B (es) | 1985-11-25 |
| EP0160252B1 (en) | 1992-08-26 |
| ES553666A0 (es) | 1987-06-16 |
| PT80328A (en) | 1985-05-01 |
| NO851538L (no) | 1985-10-24 |
| DE3586547T2 (de) | 1993-04-15 |
| AU4170085A (en) | 1985-10-31 |
| NZ211858A (en) | 1988-08-30 |
| AU580995B2 (en) | 1989-02-09 |
| ES8707245A1 (es) | 1987-07-16 |
| JPH07103130B2 (ja) | 1995-11-08 |
| DE3586547D1 (de) | 1993-02-04 |
| EP0160252A3 (en) | 1987-01-14 |
| PH23134A (en) | 1989-05-11 |
| ES557129A0 (es) | 1987-12-01 |
| ES8606362A1 (es) | 1986-04-01 |
| FI851592A0 (fi) | 1985-04-22 |
| NO167293C (no) | 1991-10-23 |
| DE3586547A1 (es) | 1993-02-04 |
| PT80328B (en) | 1987-02-16 |
| ES549180A0 (es) | 1987-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970203 |