ES509636A0 - "procedimiento para preparar nuevos compuestos de aroilimidazol-2-onas". - Google Patents
"procedimiento para preparar nuevos compuestos de aroilimidazol-2-onas".Info
- Publication number
- ES509636A0 ES509636A0 ES509636A ES509636A ES509636A0 ES 509636 A0 ES509636 A0 ES 509636A0 ES 509636 A ES509636 A ES 509636A ES 509636 A ES509636 A ES 509636A ES 509636 A0 ES509636 A0 ES 509636A0
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- aroilimidazole
- onas
- compounds
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- -1 methylenedioxy Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000005360 alkyl sulfoxide group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyurethanes Or Polyureas (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Luminescent Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23545381A | 1981-02-18 | 1981-02-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8307002A1 ES8307002A1 (es) | 1983-07-01 |
| ES509636A0 true ES509636A0 (es) | 1983-07-01 |
Family
ID=22885573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509636A Granted ES509636A0 (es) | 1981-02-18 | 1982-02-16 | "procedimiento para preparar nuevos compuestos de aroilimidazol-2-onas". |
Country Status (18)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405628A (en) * | 1981-03-05 | 1983-09-20 | Merrell Dow Pharmaceuticals Inc. | 4-Pyridylimidazolones and method of use |
| US4367236A (en) * | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
| US4410540A (en) * | 1981-11-04 | 1983-10-18 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic 4-aroylimidazolidin-2-ones |
| ZA826501B (en) * | 1982-09-06 | 1984-04-25 | Du Pont | Anti-hypertensive imidazole derivative |
| US4552880A (en) * | 1983-02-15 | 1985-11-12 | Merrell Dow Pharmaceuticals Inc. | Aroylimidazolones |
| US4556665A (en) * | 1984-07-09 | 1985-12-03 | Schering A.G. | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones |
| US20060030611A1 (en) * | 2004-03-22 | 2006-02-09 | Myogen, Inc. | Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases |
| JP2007530563A (ja) * | 2004-03-22 | 2007-11-01 | ミオゲン インコーポレイティッド | （ｓ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA803332B (en) * | 1979-06-18 | 1981-01-28 | Richardson Merrell Inc | Novel 4-aroylimidazol-2-ones |
| NZ193935A (en) * | 1979-06-18 | 1985-05-31 | Richardson Merrell Inc | 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions |
-
1982
- 1982-02-12 PH PH26861A patent/PH18106A/en unknown
- 1982-02-14 IL IL65010A patent/IL65010A0/xx unknown
- 1982-02-15 NZ NZ199733A patent/NZ199733A/en unknown
- 1982-02-15 GR GR67318A patent/GR76025B/el unknown
- 1982-02-15 ZA ZA82969A patent/ZA82969B/xx unknown
- 1982-02-15 AU AU80486/82A patent/AU558789B2/en not_active Expired
- 1982-02-15 CA CA000396247A patent/CA1173047A/en not_active Expired
- 1982-02-16 IE IE333/82A patent/IE52422B1/en not_active IP Right Cessation
- 1982-02-16 ES ES509636A patent/ES509636A0/es active Granted
- 1982-02-16 JP JP57022154A patent/JPS57150668A/ja active Granted
- 1982-02-16 DK DK067582A patent/DK161250C/da not_active IP Right Cessation
- 1982-02-17 GB GB8204721A patent/GB2093031B/en not_active Expired
- 1982-02-18 DE DE8282101233T patent/DE3274855D1/de not_active Expired
- 1982-02-18 EP EP82101233A patent/EP0058435B1/en not_active Expired
- 1982-02-18 KR KR8200715A patent/KR860001338B1/ko not_active Expired
- 1982-02-18 AT AT82101233T patent/ATE24496T1/de not_active IP Right Cessation
-
1986
- 1986-08-21 HK HK615/86A patent/HK61586A/xx not_active IP Right Cessation
- 1986-12-30 MY MY710/86A patent/MY8600710A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA82969B (en) | 1983-09-28 |
| IE52422B1 (en) | 1987-10-28 |
| EP0058435A2 (en) | 1982-08-25 |
| ATE24496T1 (de) | 1987-01-15 |
| ES8307002A1 (es) | 1983-07-01 |
| IE820333L (en) | 1982-08-18 |
| AU8048682A (en) | 1982-08-26 |
| GR76025B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-08-03 |
| PH18106A (en) | 1985-03-21 |
| HK61586A (en) | 1986-08-29 |
| DE3274855D1 (de) | 1987-02-05 |
| EP0058435A3 (en) | 1984-03-21 |
| KR830009045A (ko) | 1983-12-17 |
| MY8600710A (en) | 1986-12-31 |
| IL65010A0 (en) | 1982-04-30 |
| AU558789B2 (en) | 1987-02-12 |
| CA1173047A (en) | 1984-08-21 |
| JPH048421B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-02-17 |
| DK161250C (da) | 1991-12-09 |
| GB2093031A (en) | 1982-08-25 |
| JPS57150668A (en) | 1982-09-17 |
| DK67582A (da) | 1982-08-19 |
| EP0058435B1 (en) | 1986-12-30 |
| GB2093031B (en) | 1984-10-24 |
| NZ199733A (en) | 1985-05-31 |
| DK161250B (da) | 1991-06-17 |
| KR860001338B1 (ko) | 1986-09-15 |
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