DE68911893D1 - Antagonisten von Leukotrien D4. - Google Patents

Antagonisten von Leukotrien D4.

Info

Publication number
DE68911893D1
DE68911893D1 DE89120107T DE68911893T DE68911893D1 DE 68911893 D1 DE68911893 D1 DE 68911893D1 DE 89120107 T DE89120107 T DE 89120107T DE 68911893 T DE68911893 T DE 68911893T DE 68911893 D1 DE68911893 D1 DE 68911893D1
Authority
DE
Germany
Prior art keywords
carbon atoms
integer
lower alkyl
compounds
leukotriene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89120107T
Other languages
English (en)
Inventor
Michael Allan Stealey
Richard Mathias Weier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE68911893D1 publication Critical patent/DE68911893D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DE89120107T 1989-01-17 1989-10-30 Antagonisten von Leukotrien D4. Expired - Lifetime DE68911893D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/298,156 US4870098A (en) 1989-01-17 1989-01-17 Antagonists of leukotriene D4

Publications (1)

Publication Number Publication Date
DE68911893D1 true DE68911893D1 (de) 1994-02-10

Family

ID=23149301

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89120107T Expired - Lifetime DE68911893D1 (de) 1989-01-17 1989-10-30 Antagonisten von Leukotrien D4.

Country Status (5)

Country Link
US (1) US4870098A (de)
EP (1) EP0378765B1 (de)
JP (1) JPH02207082A (de)
AT (1) ATE99306T1 (de)
DE (1) DE68911893D1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1445013A (fr) * 1964-07-09 1966-07-08 Thomae Gmbh Dr K Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques
FR1448340A (fr) * 1964-07-09 1966-08-05 Boehringer Sohn Ingelheim Procédé pour fabriquer des nouveaux 1, 3-dioxolanes
US4097581A (en) * 1975-12-12 1978-06-27 Ciba-Geigy Corporation Dioxolane derivatives
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique
EP0411676B1 (de) * 1987-01-19 1994-06-15 Ciba-Geigy Ag Substituierte Dioxanderivate
US4808729A (en) * 1987-09-24 1989-02-28 G. D. Searle & Co. Leukotriene LTD4 and LTB4 antagonists

Also Published As

Publication number Publication date
US4870098A (en) 1989-09-26
EP0378765B1 (de) 1993-12-29
ATE99306T1 (de) 1994-01-15
JPH02207082A (ja) 1990-08-16
EP0378765A1 (de) 1990-07-25

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Legal Events

Date Code Title Description
8332 No legal effect for de