ES494352A0 - Procedimiento para preparar derivados de acidos quinolina- carboxilicos - Google Patents
Procedimiento para preparar derivados de acidos quinolina- carboxilicosInfo
- Publication number
- ES494352A0 ES494352A0 ES494352A ES494352A ES494352A0 ES 494352 A0 ES494352 A0 ES 494352A0 ES 494352 A ES494352 A ES 494352A ES 494352 A ES494352 A ES 494352A ES 494352 A0 ES494352 A0 ES 494352A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- acid derivatives
- carboxyl acid
- preparing quinoline
- quinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10677679A JPS5630964A (en) | 1979-08-22 | 1979-08-22 | Novel substituted quinolinecarboxylic acid and its preparation |
| BE2/58706A BE884824A (fr) | 1979-08-22 | 1980-08-19 | Derives de l'acide quinoleine-carboxylique et procede pour leur preparation |
| BE2059018 | 1981-02-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES494352A0 true ES494352A0 (es) | 1981-04-16 |
| ES8104233A1 ES8104233A1 (es) | 1981-04-16 |
Family
ID=27159608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES494352A Expired ES8104233A1 (es) | 1979-08-22 | 1980-08-19 | Procedimiento para preparar derivados de acidos quinolina- carboxilicos |
Country Status (16)
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4416884A (en) * | 1978-04-12 | 1983-11-22 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylbenzoheterocyclic compounds |
| JPS57176987A (en) * | 1981-04-24 | 1982-10-30 | Otsuka Pharmaceut Co Ltd | Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative |
| NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
| SE440354B (sv) * | 1981-02-19 | 1985-07-29 | Kyorin Seiyaku Kk | Kinolinkarboxylsyraderivat |
| JPS58105965A (ja) * | 1981-12-15 | 1983-06-24 | Nippon Shinyaku Co Ltd | 置換キノリンカルボン酸誘導体 |
| US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
| US4472405A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives |
| JPS59128383A (ja) * | 1982-12-29 | 1984-07-24 | Kanebo Ltd | 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤 |
| JPS59155381A (ja) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | ベンゾキノリジンカルボン酸誘導体及びその製造法 |
| DE3308908A1 (de) * | 1983-03-12 | 1984-09-13 | Bayer Ag, 5090 Leverkusen | Bakterizide mittel |
| DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| JPS59195842U (ja) * | 1983-06-13 | 1984-12-26 | クラリオン株式会社 | ラジオ受信機 |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| GB8412094D0 (en) * | 1984-05-11 | 1984-06-20 | Scras | Quinoline derivatives |
| US5468861A (en) * | 1984-06-04 | 1995-11-21 | Bayer Aktiengesellschaft | 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and alkyl esters thereof |
| DE3420743A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4550103A (en) * | 1984-07-20 | 1985-10-29 | Warner-Lambert Company | Antibacterial 1-oxo-benzoquinolizine-2-carboxylic acids |
| US4550104A (en) * | 1984-07-20 | 1985-10-29 | Warner-Lambert Company | Antibacterial thiazolo-quinolines and thiazolo-naphthyridines |
| JPS61118370A (ja) * | 1985-10-30 | 1986-06-05 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸とその製造方法 |
| ZA859283B (en) * | 1984-12-06 | 1987-07-29 | Pfizer | Substituted dihydroquinolone carboxylic acids and anti-bacterial compositions containing them |
| JPS61143363A (ja) * | 1984-12-17 | 1986-07-01 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体の製造方法 |
| JPS61143364A (ja) * | 1984-12-17 | 1986-07-01 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体の製造方法 |
| JPS61205258A (ja) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体及びその製造方法 |
| AU5427286A (en) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceutical Co. Ltd. | 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives |
| ATE77373T1 (de) * | 1985-03-21 | 1992-07-15 | Kyorin Seiyaku Kk | Verfahren zur herstellung von chinolinsaeurederivaten. |
| GB8512143D0 (en) * | 1985-05-14 | 1985-06-19 | Beecham Group Plc | Method of treatment |
| US4686221A (en) * | 1985-10-01 | 1987-08-11 | Kanebo, Ltd. | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same |
| JPS62228063A (ja) * | 1985-12-27 | 1987-10-06 | Sankyo Co Ltd | キノリンカルボン酸誘導体 |
| JPH0753715B2 (ja) * | 1986-02-25 | 1995-06-07 | 大塚製薬株式会社 | ベンゾヘテロ環化合物 |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| JPS62205060A (ja) * | 1986-03-04 | 1987-09-09 | Kyorin Pharmaceut Co Ltd | ８位置換キノロンカルボン酸誘導体 |
| JPS62215572A (ja) * | 1986-03-17 | 1987-09-22 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体 |
| ZA874696B (en) * | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
| US5591744A (en) * | 1987-04-16 | 1997-01-07 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| JPS6483068A (en) * | 1987-09-25 | 1989-03-28 | Otsuka Pharma Co Ltd | Production of benzo-heterocyclic compound |
| JPH01175936A (ja) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | ６．８−ジフルオロ−１−（２−フルオロエチル）−１，４−ジヒドロ−７−（４−メチル−１−ピペラジニル）−４−オキソ−３−キノリンカルボン酸を有効成分とする錠剤 |
| JP2526128B2 (ja) * | 1988-08-08 | 1996-08-21 | エスエス製薬株式会社 | キノロンカルボン酸誘導体 |
| US5185337A (en) * | 1989-03-29 | 1993-02-09 | Otsuka Pharmaceutical Co., Ltd. | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use |
| CA2058424A1 (en) * | 1989-07-21 | 1991-01-22 | Akihiro Shibata | Quinoline carboxylic acid derivatives |
| FR2655545B1 (fr) | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | Nouvelle application therapeutique des derives des fluoroquinolones. |
| FR2656611B1 (fr) * | 1990-01-04 | 1992-05-07 | Hoechst France | Nouvelles quinolones, leurs sels, utiles comme agents antimicrobiens, procede de preparation et leur application a titre de medicaments et compositions les renfermant. |
| FR2673426B1 (fr) * | 1991-03-01 | 1993-07-16 | Bouchara Sa | Nouvelles quinolones, leur procede de preparation et les compositions en refermant. |
| FR2675144B1 (fr) * | 1991-04-10 | 1995-06-16 | Bouchara Sa | Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant. |
| US5532239A (en) * | 1993-08-02 | 1996-07-02 | Assistance Publique - Hopitaux De Paris | Therapeutic application of fluoroquinolone derivatives |
| JP3676415B2 (ja) * | 1994-03-01 | 2005-07-27 | 石原産業株式会社 | ５，７−ジクロロ−４−ヒドロキシキノリンの製造方法 |
| SE9904108D0 (sv) * | 1999-11-15 | 1999-11-15 | New Pharma Research Ab | Nya föreningar |
| US7973022B2 (en) | 2006-02-17 | 2011-07-05 | Idexx Laboratories, Inc. | Fluoroquinolone carboxylic acid salt compositions |
| US20070197548A1 (en) | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7101049A (enrdf_load_stackoverflow) * | 1970-01-28 | 1971-07-30 | ||
| BE793524A (fr) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | Acides benzoquinolizine-carboxyliques et leurs derives |
| US4156726A (en) * | 1974-12-07 | 1979-05-29 | Fisons Limited | 4-Oxo-2-carboxyl quinoline derivatives used as antiallergic compounds |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| JPS54112877A (en) | 1978-02-20 | 1979-09-04 | Sumitomo Chem Co Ltd | Preparation of 1-substituted-1,4-dihydro-4-oxo-3-pyridine carboxylic acid derivatives |
| DE2914258A1 (de) * | 1978-04-12 | 1979-10-25 | Otsuka Pharma Co Ltd | Piperazinylbenzoheterozyklische verbindungen, verfahren zu deren herstellung und mittel, welche diese enthalten |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
-
1979
- 1979-08-22 JP JP10677679A patent/JPS5630964A/ja active Pending
-
1980
- 1980-08-04 SE SE8005534A patent/SE440353B/sv not_active IP Right Cessation
- 1980-08-06 AU AU61122/80A patent/AU533141B2/en not_active Expired
- 1980-08-11 IT IT24111/80A patent/IT1132392B/it active
- 1980-08-14 CH CH614680A patent/CH645641A5/de not_active IP Right Cessation
- 1980-08-19 ES ES494352A patent/ES8104233A1/es not_active Expired
- 1980-08-19 BE BE2/58706A patent/BE884824A/fr not_active IP Right Cessation
- 1980-08-21 SU SU802968349A patent/SU978727A3/ru active
- 1980-08-21 HU HU802072A patent/HU184817B/hu unknown
- 1980-08-21 CA CA000358778A patent/CA1159454A/en not_active Expired
- 1980-08-21 FR FR8018279A patent/FR2463771A1/fr active Granted
- 1980-08-22 DE DE3031767A patent/DE3031767C3/de not_active Expired - Lifetime
- 1980-08-22 GB GB8027372A patent/GB2057440B/en not_active Expired
-
1981
- 1981-02-19 BE BE2/59018A patent/BE887574R/fr not_active IP Right Cessation
- 1981-03-03 SU SU813254244A patent/SU1015827A3/ru active
-
1986
- 1986-09-04 SG SG713/86A patent/SG71386G/en unknown
- 1986-12-18 HK HK984/86A patent/HK98486A/xx not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY155/87A patent/MY8700155A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG71386G (en) | 1987-03-27 |
| GB2057440B (en) | 1983-10-12 |
| CH645641A5 (de) | 1984-10-15 |
| GB2057440A (en) | 1981-04-01 |
| MY8700155A (en) | 1987-12-31 |
| JPS5630964A (en) | 1981-03-28 |
| SE8005534L (sv) | 1981-02-23 |
| SU978727A3 (ru) | 1982-11-30 |
| HU184817B (en) | 1984-10-29 |
| DE3031767A1 (de) | 1981-03-26 |
| FR2463771B1 (enrdf_load_stackoverflow) | 1983-04-22 |
| ES8104233A1 (es) | 1981-04-16 |
| FR2463771A1 (fr) | 1981-02-27 |
| AU6112280A (en) | 1981-02-26 |
| BE887574R (fr) | 1981-06-15 |
| CA1159454A (en) | 1983-12-27 |
| IT8024111A0 (it) | 1980-08-11 |
| SE440353B (sv) | 1985-07-29 |
| AU533141B2 (en) | 1983-11-03 |
| BE884824A (fr) | 1980-12-16 |
| DE3031767C2 (enrdf_load_stackoverflow) | 1994-04-14 |
| IT1132392B (it) | 1986-07-02 |
| DE3031767C3 (de) | 1994-04-14 |
| SU1015827A3 (ru) | 1983-04-30 |
| HK98486A (en) | 1986-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010417 |