ES489967A1 - Procedimiento mejorado para la fabricacion de granulos de pancreatina - Google Patents
Procedimiento mejorado para la fabricacion de granulos de pancreatinaInfo
- Publication number
- ES489967A1 ES489967A1 ES489967A ES489967A ES489967A1 ES 489967 A1 ES489967 A1 ES 489967A1 ES 489967 A ES489967 A ES 489967A ES 489967 A ES489967 A ES 489967A ES 489967 A1 ES489967 A1 ES 489967A1
- Authority
- ES
- Spain
- Prior art keywords
- pancreatin
- pellets
- pellet
- extrusion
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Abstract
Procedimiento mejorado para la fabricación de gránulos de pancreatina, caracterizado porque se extruye una masa conformable que contiene disolventes favorables a las enzimas y polvo de pancreatina en una prensa de extrusión, eventualmente con enfriamiento, se divide el material extruído en recortes de extrusión, se seca y se trata ulteriormente según métodos conocidos en sí.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2923279A DE2923279B1 (de) | 1979-06-08 | 1979-06-08 | Verfahren zur Herstellung von Pankreatin-Pellets |
Publications (1)
Publication Number | Publication Date |
---|---|
ES489967A1 true ES489967A1 (es) | 1980-10-01 |
Family
ID=6072800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES489967A Expired ES489967A1 (es) | 1979-06-08 | 1980-03-27 | Procedimiento mejorado para la fabricacion de granulos de pancreatina |
Country Status (22)
Country | Link |
---|---|
US (1) | US4280971A (es) |
EP (1) | EP0021129B2 (es) |
JP (1) | JPS55164622A (es) |
KR (1) | KR850000625B1 (es) |
AR (1) | AR228427A1 (es) |
AT (1) | ATE6030T1 (es) |
AU (1) | AU532838B2 (es) |
CA (1) | CA1142082A (es) |
DD (1) | DD151184A5 (es) |
DE (2) | DE2923279B1 (es) |
DK (1) | DK158932C (es) |
ES (1) | ES489967A1 (es) |
FI (1) | FI84022C (es) |
GR (1) | GR69290B (es) |
IE (1) | IE49584B1 (es) |
IL (1) | IL59893A (es) |
NO (1) | NO158949C (es) |
NZ (1) | NZ193476A (es) |
PH (1) | PH16898A (es) |
PT (1) | PT71136A (es) |
SU (1) | SU1256690A3 (es) |
ZA (1) | ZA802919B (es) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9259393B2 (en) | 2000-11-15 | 2016-02-16 | Aptalis Pharma S.R.L. | Microspheres of pancreatic enzymes with high stability and production method thereof |
US9976171B2 (en) | 2011-08-08 | 2018-05-22 | Allergan Pharmaceuticals International Limited | Method for dissolution testing of solid compositions containing digestive enzymes |
US10087493B2 (en) | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
US10184121B2 (en) | 2013-06-28 | 2019-01-22 | Allergan Pharmaceuticals International Limited | Methods for removing viral contaminants from pancreatic extracts |
US10206882B2 (en) | 2007-02-20 | 2019-02-19 | Allergan Pharmaceuticals International Limited | Stable digestive enzyme compositions |
US10993996B2 (en) | 2013-08-09 | 2021-05-04 | Allergan Pharmaceuticals International Limited | Digestive enzyme composition suitable for enteral administration |
US11364205B2 (en) | 2010-10-01 | 2022-06-21 | Societe Des Produits Nestle S.A. | Stable low digestive enzyme content formulation |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61170390A (ja) * | 1985-01-25 | 1986-08-01 | Agency Of Ind Science & Technol | 酵素含有多糖複合体 |
GB8624628D0 (en) * | 1986-10-14 | 1986-11-19 | Scras | Soluble/splitable tablets |
DE3642853A1 (de) * | 1986-12-16 | 1988-06-23 | Ulrich Von Dr Ing Pidoll | Arzneimittel |
IT1205716B (it) * | 1987-01-21 | 1989-03-31 | Samil Spa | Procedimento per la preparazione di microsfere gastroresistenti ed enterosolubili di enzima digestivo e preparato faramceutico a microsfere cosi' prodotto |
DE3721574A1 (de) * | 1987-06-30 | 1989-01-12 | Kettelhack Riker Pharma Gmbh | Arzneimittel in form von pellets mit enzymatisch kontrollierter arzneistoff-freisetzung |
US4944944A (en) * | 1987-11-19 | 1990-07-31 | Oklahoma Medical Research Foundation | Dietary compositions and methods using bile salt-activated lipase |
KR100229754B1 (ko) * | 1989-11-24 | 1999-11-15 | 샬러 한스, 하우스 한스 루돌프 | 판크레아틴구형입자, 이의 제조방법 및 이를 함유하는 약제학적 조성물 |
WO1993007859A1 (en) * | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
US5262172A (en) * | 1992-06-19 | 1993-11-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing buffered bile acids |
US5260074A (en) * | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
US5302400A (en) * | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
US5415872A (en) * | 1992-06-22 | 1995-05-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
US5234697A (en) * | 1992-06-22 | 1993-08-10 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
US5578304A (en) * | 1992-06-22 | 1996-11-26 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
US5460812A (en) * | 1992-06-22 | 1995-10-24 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
US5352682A (en) * | 1993-03-08 | 1994-10-04 | Digestive Care Inc. | Compositions containing salts of bile acid-aminosalicylate conjugates |
GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
US5750104A (en) * | 1996-05-29 | 1998-05-12 | Digestive Care Inc. | High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith |
US5861291A (en) * | 1997-02-24 | 1999-01-19 | Biozymes Inc. | Method for producing pancreatin which contains low amounts of residual organic solvent and product thereof |
DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
US6632429B1 (en) | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
KR100367659B1 (ko) * | 2000-05-08 | 2003-01-14 | 주식회사 바이넥스 | 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법 |
GB0012056D0 (en) * | 2000-05-18 | 2000-07-12 | Consejo Superior Investigacion | Model for neurodegenerative disease |
US20070053895A1 (en) * | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
KR20020085376A (ko) * | 2001-05-08 | 2002-11-16 | (주) 인터코텍 | 화장품 조성물 |
US20040197321A1 (en) * | 2002-03-19 | 2004-10-07 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
US20030180279A1 (en) * | 2002-03-19 | 2003-09-25 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
PL1729797T3 (pl) | 2004-03-22 | 2009-02-27 | Abbott Laboratories Gmbh | Doustne kompozycje farmaceutyczne produktów zawierających lipazę, a zwłaszcza pankreatynę, zawierające środki powierzchniowo czynne |
US7153504B2 (en) * | 2004-07-30 | 2006-12-26 | Can Technologies, Inc. | Stabilized pancreas product |
US20060198838A1 (en) * | 2004-09-28 | 2006-09-07 | Fallon Joan M | Combination enzyme for cystic fibrosis |
CN101233229B (zh) * | 2005-07-29 | 2013-05-01 | 雅培实验室有限公司 | 制备消毒的胰酶粉末的方法 |
SI1931316T1 (sl) | 2005-08-15 | 2010-06-30 | Solvay Pharm Gmbh | Farmacevtski sestavki z nadzorovanim sproščanjem za kislinsko labilna zdravila |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
US20070116695A1 (en) * | 2005-09-21 | 2007-05-24 | Fallon Joan M | Pharmaceutical preparations for attention deficit disorder, attention deficit hyperactivity disorder and other associated disorders |
US10072256B2 (en) | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
DE102007025858A1 (de) | 2007-06-01 | 2008-12-04 | Grünenthal GmbH | Verfahren zur Herstellung einer Arzneimitteldarreichungsform |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
US9320780B2 (en) * | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
PL2318035T3 (pl) * | 2008-07-01 | 2019-10-31 | Curemark Llc | Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego |
US20100021505A1 (en) * | 2008-07-28 | 2010-01-28 | Tibor Sipos | Composition and method to prevent or reduce diarrhea and steatorrhea in HIV patients |
US10776453B2 (en) | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
EP2165717A1 (de) | 2008-08-27 | 2010-03-24 | Nordmark Arzneimittel GmbH & Co.KG | Verfahren zur Verringerung der viralen und mikrobiellen Belastung feststoffhaltiger biologischer Extrakte |
US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
EP2373791B1 (en) | 2009-01-06 | 2016-03-30 | Curelon LLC | Compositions comprising protease, amylase and lipase for use in the treatment of staphylococcus aureus infections |
KR20170005191A (ko) | 2009-01-06 | 2017-01-11 | 큐어론 엘엘씨 | 이. 콜라이에 의한 구강 감염의 치료 또는 예방을 위한 조성물 및 방법 |
ES2488407T3 (es) | 2009-01-29 | 2014-08-27 | Nordmark Arzneimittel Gmbh & Co. Kg | Preparación farmacéutica que contiene lipasa de origen bacteriano |
US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
EP2295039B2 (de) | 2009-08-28 | 2022-10-26 | Nordmark Pharma GmbH | Verfahren zur Herstellung von Pankreatin-Pellets, insbesondere Pankreatin-Mikropellets, und hiernach hergestellte Pankreatin-Pellets |
WO2011050135A1 (en) | 2009-10-21 | 2011-04-28 | Curemark Llc | Methods and compositions for the prevention and treatment of influenza |
DE202011000728U1 (de) | 2011-03-30 | 2011-06-09 | Nordmark Arzneimittel GmbH & Co. KG, 25436 | Pankreatin-Pellets, insbesondere Pankreatin-Mikropellets |
PL2489349T3 (pl) | 2011-02-17 | 2014-09-30 | Nordmark Arzneimittel Gmbh & Co Kg | Granulki pankreatynowe, zwłaszcza mikrogranulki pankreatynowe, oraz sposób ich produkcji |
MX362974B (es) | 2011-04-21 | 2019-02-28 | Curemark Llc | Compuestos para el tratamiento de alteraciones neuropsiquiatricas. |
US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
US20180028454A1 (en) | 2015-02-04 | 2018-02-01 | Abbvie Inc. | Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency |
US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3154603A (en) * | 1961-08-02 | 1964-10-27 | American Cyanamid Co | Process for the preparation of spherical contact particles |
DE1617363B1 (de) * | 1967-12-06 | 1972-05-31 | Boehringer & Soehne Gmbh | Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate |
DE2035739A1 (en) * | 1970-07-18 | 1972-01-27 | Röhm FmbH, 6100 Darmstadt | Oral enzyme prepsn - consisting of granulate with gastric juices-resistant coating in tablet or capsule form |
GB1342409A (en) * | 1970-07-23 | 1974-01-03 | Ciba Geigy Ag | Flowable pancreatin preparation of low microorgan ism content and a process for its manufacture |
BE795766A (fr) * | 1972-02-22 | 1973-08-22 | Lilly Co Eli | Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules |
US3922339A (en) * | 1974-06-20 | 1975-11-25 | Kv Pharm Co | Sustained release medicant |
DE2512746C3 (de) * | 1975-03-22 | 1980-04-24 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin |
GB1509866A (en) * | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
JPS5347513A (en) * | 1976-10-14 | 1978-04-28 | Meiji Seika Kaisha Ltd | Preparation of enzymatic agent |
-
1979
- 1979-06-08 DE DE2923279A patent/DE2923279B1/de active Granted
- 1979-10-31 US US06/089,963 patent/US4280971A/en not_active Expired - Lifetime
-
1980
- 1980-03-27 ES ES489967A patent/ES489967A1/es not_active Expired
- 1980-03-28 AR AR280494A patent/AR228427A1/es active
- 1980-04-10 IE IE733/80A patent/IE49584B1/en not_active IP Right Cessation
- 1980-04-17 AU AU57552/80A patent/AU532838B2/en not_active Expired
- 1980-04-18 NZ NZ193476A patent/NZ193476A/xx unknown
- 1980-04-21 SU SU802911402A patent/SU1256690A3/ru active
- 1980-04-22 IL IL59893A patent/IL59893A/xx unknown
- 1980-04-23 PT PT71136A patent/PT71136A/pt not_active IP Right Cessation
- 1980-05-07 PH PH23983A patent/PH16898A/en unknown
- 1980-05-16 ZA ZA00802919A patent/ZA802919B/xx unknown
- 1980-05-28 DD DD80221415A patent/DD151184A5/de unknown
- 1980-05-31 EP EP80103046A patent/EP0021129B2/de not_active Expired
- 1980-05-31 AT AT80103046T patent/ATE6030T1/de not_active IP Right Cessation
- 1980-05-31 DE DE8080103046T patent/DE3066366D1/de not_active Expired
- 1980-06-03 FI FI801779A patent/FI84022C/fi not_active IP Right Cessation
- 1980-06-04 KR KR1019800002205A patent/KR850000625B1/ko active
- 1980-06-06 DK DK244480A patent/DK158932C/da not_active IP Right Cessation
- 1980-06-06 JP JP7565880A patent/JPS55164622A/ja active Granted
- 1980-06-06 GR GR62148A patent/GR69290B/el unknown
- 1980-06-06 CA CA000353493A patent/CA1142082A/en not_active Expired
- 1980-06-06 NO NO801690A patent/NO158949C/no unknown
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9259393B2 (en) | 2000-11-15 | 2016-02-16 | Aptalis Pharma S.R.L. | Microspheres of pancreatic enzymes with high stability and production method thereof |
US9884025B2 (en) | 2000-11-15 | 2018-02-06 | Aptalis Pharma S.R.L. | Microspheres of pancreatic enzymes with high stability and production method thereof |
US10206882B2 (en) | 2007-02-20 | 2019-02-19 | Allergan Pharmaceuticals International Limited | Stable digestive enzyme compositions |
US10087493B2 (en) | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
US11364205B2 (en) | 2010-10-01 | 2022-06-21 | Societe Des Produits Nestle S.A. | Stable low digestive enzyme content formulation |
US9976171B2 (en) | 2011-08-08 | 2018-05-22 | Allergan Pharmaceuticals International Limited | Method for dissolution testing of solid compositions containing digestive enzymes |
US10184121B2 (en) | 2013-06-28 | 2019-01-22 | Allergan Pharmaceuticals International Limited | Methods for removing viral contaminants from pancreatic extracts |
US10993996B2 (en) | 2013-08-09 | 2021-05-04 | Allergan Pharmaceuticals International Limited | Digestive enzyme composition suitable for enteral administration |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES489967A1 (es) | Procedimiento mejorado para la fabricacion de granulos de pancreatina | |
CA1025712A (en) | Process for the manufacture of composite structures constituted by cellulosic and polymeric materials | |
ES436207A1 (es) | Mejoras en un procedimiento relativo a sistemas modificado- res de espuma. | |
BR7604984A (pt) | Processo para fabricacao de explosivo composito termoestavel explosivo assim obtido,polvora a moldar reticulada,e carregamento explosivo | |
CA1011491A (en) | Polymeric compositions and process for their manufacture | |
DE3063223D1 (en) | Process for the production of graft polymer, the polymer so produced and polystyrene compositions containing it as an impact modifier | |
KR860001613A (ko) | 흡착제용 해조류 과립의 제조방법 | |
CA977972A (en) | Manufacture of progressive burning propellants, and product | |
ZA754685B (en) | 9.3",4"-triacyl ester of the antibiotic sf-837 m1 substance and the production thereof | |
JPS5566508A (en) | Valepotiat medicine and its manufacture | |
CA1019499A (en) | Manufacture of carbodiimide foams | |
CA925470A (en) | Production of improved polymeric materials using electrical gas discharges | |
JPS5222593A (en) | Production process of granular sulfur | |
ES438445A1 (es) | Procedimiento para la preparacion de un agente pesticida quedesprende fosfina. | |
IT1007925B (it) | Composizioni contenenti miscele di policarbamoil solfonati e di altri polimeri e loro applicazio ni | |
CA1027696A (en) | Process for the production of polymeric acetals containing urethane, carbamide and amide groups | |
JPS5424289A (en) | Production of spherical diatomaceous earth carrier | |
IE42095L (en) | Granular oxymethylene polymers | |
OA05031A (fr) | Nouveaux arylcarbamates N-sulfénylés, leur procédé de préparation et leur application comme insecticides. | |
ZA757282B (en) | Process for the manufacture of double base propellant charges for rockets, ejector charges and the like | |
AU475467B2 (en) | Process and apparatus forthe production of smokeless, odourless, solid fuel | |
CA1007457A (en) | Explosive compositions fueled, sensitized and thickened by solid, finely divided polysaccharide polymer of plant origin | |
ZA806244B (en) | Ergot peptide alkaloides,their production,pharmaceutical compositions and their use as pharamceuticals | |
GB1443289A (en) | Mouldable compositions comprising polyvinyl nitrate | |
CA921780A (en) | Process for production of glass-filled thermoplastic pellets suitable for blending with thermoplastic, and such pellets |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted |