ES477889A1 - Procedimiento para la obtencion de n1-glucofuranosid-6-il- n3-nitrosoureas. - Google Patents

Procedimiento para la obtencion de n1-glucofuranosid-6-il- n3-nitrosoureas.

Info

Publication number
ES477889A1
ES477889A1 ES477889A ES477889A ES477889A1 ES 477889 A1 ES477889 A1 ES 477889A1 ES 477889 A ES477889 A ES 477889A ES 477889 A ES477889 A ES 477889A ES 477889 A1 ES477889 A1 ES 477889A1
Authority
ES
Spain
Prior art keywords
glycofuranosyl
manufacture
pharmaceutical preparations
unsubstituted
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477889A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES477889A1 publication Critical patent/ES477889A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Nuevos derivados de nitrosoúrea, especialmente N1- glucofuranosid-6-il-N3-nitrosoúrea de fórmula general I **(Fórmula)** donde R1, R2 y R5 significan hidrógeno, alquilo, en caso dado sustituido, o aralquilo o arilo, R1 y R2 juntos pueden representar también alquilideno o cicloalquilideno, y R6 significa alquilo, en caso dado sustituido. Los restos, radiales o compuestos modificados a continuación con la expresión "inferior" contienen, siempre que no se indique otra cosa, preferentemente hasta 7, en primer lugar hasta 4 átomos de carbono.
ES477889A 1978-02-21 1979-02-20 Procedimiento para la obtencion de n1-glucofuranosid-6-il- n3-nitrosoureas. Expired ES477889A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH184978 1978-02-21

Publications (1)

Publication Number Publication Date
ES477889A1 true ES477889A1 (es) 1979-08-01

Family

ID=4220040

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477889A Expired ES477889A1 (es) 1978-02-21 1979-02-20 Procedimiento para la obtencion de n1-glucofuranosid-6-il- n3-nitrosoureas.

Country Status (23)

Country Link
EP (1) EP0003788B1 (es)
JP (1) JPS54122226A (es)
KR (1) KR820000419B1 (es)
AR (1) AR227004A1 (es)
AT (1) AT362389B (es)
AU (1) AU525495B2 (es)
CA (1) CA1123825A (es)
CS (2) CS203947B2 (es)
CY (1) CY1264A (es)
DE (1) DE2961524D1 (es)
DK (1) DK73579A (es)
ES (1) ES477889A1 (es)
FI (1) FI65782C (es)
GR (1) GR74066B (es)
HK (1) HK96984A (es)
HU (1) HU179949B (es)
IL (1) IL56696A (es)
NO (1) NO146398C (es)
NZ (1) NZ189703A (es)
PL (2) PL117894B1 (es)
PT (1) PT69253A (es)
SU (2) SU913944A3 (es)
ZA (1) ZA79803B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157684A (en) * 1961-02-13 1964-11-17 Atomic Energy Authority Uk Tritiated-2-methyl-naphthaquinol-(1, 4)-diphosphoric acids
JPS5681596A (en) * 1979-12-07 1981-07-03 Tokyo Tanabe Co Ltd Glucopyranose-nitrosourea derivative, carcinostatic agent consisting of the same and preparation
US4387220A (en) * 1980-11-05 1983-06-07 The Nissin Sugar Manufacturing Co., Ltd. Nitrosourea derivatives of sucrose
FR2614304A1 (fr) * 1987-04-22 1988-10-28 Sanofi Sa Derives de nitrosourees, leur nouveau procede de preparation et leurs applications therapeutiques.
PL233967B1 (pl) 2016-03-24 2019-12-31 Naturlen Spólka Z Ograniczona Odpowiedzialnoscia Sposób wytwarzania materiału opatrunkowego z zastosowaniem włókien lnianych oraz materiał opatrunkowy z zastosowaniem włókien lnianych

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5175072A (ja) * 1974-12-18 1976-06-29 Tokyo Tanabe Co Ribofuranoozunonitorosokarubamirujudotaino seizoho
JPS52151125A (en) * 1976-05-18 1977-12-15 Tokyo Tanabe Co Process for manufacturing chloroethylnitrosourea derivatives of alkylglucopyranose
FI65781C (fi) * 1977-06-15 1984-07-10 Ciba Geigy Ag Analogifoerfarande foer framstaellning av terapeutiskt verkande n1-glukofuranosid-6-yl-n3-nitroso-urinaemnen

Also Published As

Publication number Publication date
NO146398C (no) 1982-09-22
CS203946B2 (en) 1981-03-31
SU913944A3 (en) 1982-03-15
PL213595A2 (es) 1980-04-08
AR227004A1 (es) 1982-09-15
JPS54122226A (en) 1979-09-21
NZ189703A (en) 1981-07-13
EP0003788A3 (en) 1979-10-31
FI790556A (fi) 1979-08-22
PT69253A (de) 1979-03-01
IL56696A0 (en) 1979-05-31
CY1264A (en) 1984-11-23
DE2961524D1 (en) 1982-02-04
EP0003788B1 (de) 1981-12-09
GR74066B (es) 1984-06-06
ZA79803B (en) 1980-10-29
EP0003788A2 (de) 1979-09-05
SU1028250A3 (ru) 1983-07-07
AU4439379A (en) 1979-08-30
PL219884A1 (es) 1980-07-14
PL117325B1 (en) 1981-07-31
IL56696A (en) 1982-08-31
AU525495B2 (en) 1982-11-11
PL117894B1 (en) 1981-08-31
FI65782C (fi) 1984-07-10
HU179949B (en) 1983-01-28
AT362389B (de) 1981-05-11
NO790564L (no) 1979-08-22
DK73579A (da) 1979-08-22
HK96984A (en) 1984-12-21
ATA128979A (de) 1980-10-15
KR820000419B1 (ko) 1982-04-01
CA1123825A (en) 1982-05-18
FI65782B (fi) 1984-03-30
NO146398B (no) 1982-06-14
CS203947B2 (en) 1981-03-31

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