ES476480A1 - Metodo de producir un antibiotico. - Google Patents
Metodo de producir un antibiotico.Info
- Publication number
- ES476480A1 ES476480A1 ES476480A ES476480A ES476480A1 ES 476480 A1 ES476480 A1 ES 476480A1 ES 476480 A ES476480 A ES 476480A ES 476480 A ES476480 A ES 476480A ES 476480 A1 ES476480 A1 ES 476480A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotic
- germicide
- disinfectant
- cultivating
- elaborated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/38—Pseudomonas
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Método de producir un antibiótico , caracterizado por cultivar un microorganismo que pertenece al género Pseudomonas y que es capaz de producir dicho antibiótico en un medio de cultivo para tener dicho antibiótico elaborado y acumulado en el caldo cultivado, y recuperar dicho antibiótico, actuándose bajo condiciones tales que el antibiótico producido tenga las siguientes características: (1) Punto de fusión: 120ºC (sinterización), 130ºC(descom.) (2) Aspecto: Polvo blanco (3) Análisis elemental (%) C 34,99 +-0,5 H 5,58+-0,5 N 13,30 +-0,5 C38,13 +-0,5 S 7,70 +-0,5 (secado a 40ºC durante 6 horas sobre pentóxido de fósforo bajo presión reducida) (4) Espectro de absorción de ultravioletas: sin absorciones características en 210 nm (5) Espectro de absorción de infrarroJo [Kbr, absorciones dominantes (números de onda,cm-1)] 1770,1650,1530,1240,1043, (6) Rotación específica [alfa]23 d + 94º+-10ºc=0,35,H2O) (7) Solubilidad: insoluble en éter de petróleo , hexano, éter de dietilo, benceno, acetado deetilo y cloroformo; escasamente soluble en etanol, piridina y acetona; soluble en metanol y sulfóxido de dimetilo; y fácilmente soluble en agua. (8) Basicidad, neutralidad o acidez: Acido, (9) Peso molecular : 400+-20 (por titulometría) (10) Reacciones de color: Positivas; reacciones con ainhidrina y permanganto potásico, negativas: reacciones con cloruro férrico-ferricianato potásico y de Sakaguchi y Molisch; dudosamente positiva: reacción de Ehrlich.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52160308A JPS6046955B2 (ja) | 1977-12-30 | 1977-12-30 | 抗生物質g−6302 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES476480A1 true ES476480A1 (es) | 1979-04-16 |
Family
ID=15712141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476480A Expired ES476480A1 (es) | 1977-12-30 | 1978-12-29 | Metodo de producir un antibiotico. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4229436A (es) |
JP (1) | JPS6046955B2 (es) |
AU (1) | AU521534B2 (es) |
BE (1) | BE873217A (es) |
CA (1) | CA1113873A (es) |
CH (1) | CH644593A5 (es) |
CS (1) | CS208768B2 (es) |
DE (1) | DE2855949A1 (es) |
DK (1) | DK147452C (es) |
ES (1) | ES476480A1 (es) |
FR (1) | FR2413399A1 (es) |
GB (1) | GB2011380B (es) |
HU (1) | HU179350B (es) |
IT (1) | IT1202812B (es) |
NL (1) | NL7812493A (es) |
PH (1) | PH15534A (es) |
SE (1) | SE433229B (es) |
SU (1) | SU1003761A3 (es) |
ZA (1) | ZA786882B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ196202A (en) * | 1980-02-07 | 1984-07-31 | Squibb & Sons Inc | Beta-lactam antibiotics (of azetidine-sulphonic acid type) |
US4775670A (en) * | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
EP0050965A1 (en) * | 1980-10-23 | 1982-05-05 | Takeda Chemical Industries, Ltd. | Beta-lactamase inhibitory composition |
WO1982001873A1 (en) * | 1980-12-05 | 1982-06-10 | Takeda Chemical Industries Ltd | 1-sulfo-2-oxoazetidine derivatives and process for their preparation |
MX7096E (es) * | 1980-12-05 | 1987-06-19 | Takeda Chemical Industries Ltd | Metodo para preparacion de derivados de 2-oxoazetidina |
US4675397A (en) * | 1980-12-05 | 1987-06-23 | Takeda Chemical Industries, Ltd. | 1-sulfo-2-oxoazetidine derivatives and their production |
US4782147A (en) * | 1980-12-05 | 1988-11-01 | Takeda Chemical Industries, Ltd. | 1-sulfo-2-oxoazetidine derivatives and their production |
US4673739A (en) * | 1980-12-05 | 1987-06-16 | Takeda Chemical Industries, Ltd. | 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production |
US4572801A (en) * | 1981-04-30 | 1986-02-25 | Takeda Chemical Industries, Ltd. | 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production |
US4504655A (en) * | 1981-07-07 | 1985-03-12 | Takeda Chemical Industries, Ltd. | Substances potentiating the activity of antibiotics and their production |
JPS588089A (ja) * | 1981-07-07 | 1983-01-18 | Takeda Chem Ind Ltd | 抗菌性増強物質f2およびその製造法 |
JPS58141786A (ja) * | 1982-02-15 | 1983-08-23 | Takeda Chem Ind Ltd | 抗菌性増強物質f3およびその製造法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3629405A (en) * | 1969-07-28 | 1971-12-21 | Lilly Co Eli | Antibiotics a4993a and a4993b and process for producing the antibiotics |
-
1977
- 1977-12-30 JP JP52160308A patent/JPS6046955B2/ja not_active Expired
-
1978
- 1978-12-07 AU AU42307/78A patent/AU521534B2/en not_active Expired
- 1978-12-15 US US05/971,089 patent/US4229436A/en not_active Expired - Lifetime
- 1978-12-17 ZA ZA786882A patent/ZA786882B/xx unknown
- 1978-12-18 PH PH21956A patent/PH15534A/en unknown
- 1978-12-21 HU HU78TA1505A patent/HU179350B/hu unknown
- 1978-12-22 NL NL7812493A patent/NL7812493A/xx not_active Application Discontinuation
- 1978-12-22 CS CS788842A patent/CS208768B2/cs unknown
- 1978-12-23 DE DE19782855949 patent/DE2855949A1/de active Granted
- 1978-12-27 DK DK582978A patent/DK147452C/da not_active IP Right Cessation
- 1978-12-28 SE SE7813384A patent/SE433229B/sv unknown
- 1978-12-28 SU SU782704454A patent/SU1003761A3/ru active
- 1978-12-28 FR FR7836628A patent/FR2413399A1/fr active Granted
- 1978-12-29 ES ES476480A patent/ES476480A1/es not_active Expired
- 1978-12-29 BE BE192682A patent/BE873217A/xx not_active IP Right Cessation
- 1978-12-29 CH CH1330178A patent/CH644593A5/de not_active IP Right Cessation
- 1978-12-29 CA CA318,813A patent/CA1113873A/en not_active Expired
- 1978-12-29 IT IT31423/78A patent/IT1202812B/it active
-
1979
- 1979-01-02 GB GB7987A patent/GB2011380B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2855949C2 (es) | 1987-06-04 |
AU521534B2 (en) | 1982-04-08 |
HU179350B (en) | 1982-10-28 |
CH644593A5 (de) | 1984-08-15 |
IT7831423A0 (it) | 1978-12-29 |
BE873217A (fr) | 1979-06-29 |
DK582978A (da) | 1979-07-01 |
GB2011380B (en) | 1982-08-18 |
US4229436A (en) | 1980-10-21 |
ZA786882B (en) | 1980-02-27 |
FR2413399B1 (es) | 1982-11-19 |
IT1202812B (it) | 1989-02-09 |
SE7813384L (sv) | 1979-07-01 |
DE2855949A1 (de) | 1979-07-05 |
DK147452C (da) | 1985-02-18 |
GB2011380A (en) | 1979-07-11 |
CA1113873A (en) | 1981-12-08 |
FR2413399A1 (fr) | 1979-07-27 |
DK147452B (da) | 1984-08-13 |
CS208768B2 (en) | 1981-09-15 |
AU4230778A (en) | 1979-07-05 |
NL7812493A (nl) | 1979-07-03 |
JPS54163501A (en) | 1979-12-26 |
PH15534A (en) | 1983-02-09 |
SE433229B (sv) | 1984-05-14 |
JPS6046955B2 (ja) | 1985-10-18 |
SU1003761A3 (ru) | 1983-03-07 |
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