ES476109A1 - Procedimiento para la preparacion de derivados de cefalospo-rina - Google Patents
Procedimiento para la preparacion de derivados de cefalospo-rinaInfo
- Publication number
- ES476109A1 ES476109A1 ES476109A ES476109A ES476109A1 ES 476109 A1 ES476109 A1 ES 476109A1 ES 476109 A ES476109 A ES 476109A ES 476109 A ES476109 A ES 476109A ES 476109 A1 ES476109 A1 ES 476109A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- see image
- preparation
- general formula
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 aminocarbonylmethyl Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003951 lactams Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772758001 DE2758001A1 (de) | 1977-12-24 | 1977-12-24 | Cephalosporinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES476109A1 true ES476109A1 (es) | 1979-10-16 |
Family
ID=6027279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES476109A Expired ES476109A1 (es) | 1977-12-24 | 1978-12-19 | Procedimiento para la preparacion de derivados de cefalospo-rina |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4293550A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0002765B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5495592A (cg-RX-API-DMAC7.html) |
| AT (1) | AT365599B (cg-RX-API-DMAC7.html) |
| AU (1) | AU534258B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1109461A (cg-RX-API-DMAC7.html) |
| DE (2) | DE2758001A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK578978A (cg-RX-API-DMAC7.html) |
| EG (1) | EG13762A (cg-RX-API-DMAC7.html) |
| ES (1) | ES476109A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI66007C (cg-RX-API-DMAC7.html) |
| GR (1) | GR65234B (cg-RX-API-DMAC7.html) |
| HU (1) | HU184140B (cg-RX-API-DMAC7.html) |
| IE (1) | IE48147B1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL56284A (cg-RX-API-DMAC7.html) |
| NO (1) | NO784366L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ189266A (cg-RX-API-DMAC7.html) |
| PH (1) | PH15925A (cg-RX-API-DMAC7.html) |
| PT (1) | PT68964A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA787209B (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703046A (en) * | 1978-09-08 | 1987-10-27 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and processes for preparation thereof |
| NL8005440A (nl) * | 1979-10-02 | 1981-04-06 | Glaxo Group Ltd | Cefalosporinen met antibiotische werking. |
| US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
| DE3006888A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| JPS57131794A (en) * | 1980-12-31 | 1982-08-14 | Fujisawa Pharmaceut Co Ltd | Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent |
| US4427677A (en) * | 1980-12-31 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| EP0055465B1 (en) * | 1980-12-31 | 1989-08-23 | Fujisawa Pharmaceutical Co., Ltd. | 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof |
| US4618606A (en) * | 1982-11-17 | 1986-10-21 | Toyama Chemical Co., Ltd. | Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins |
| EP1059293A1 (en) * | 1995-10-12 | 2000-12-13 | Microcide Pharmaceuticals, Inc. | Novel amino chlorothiazole compounds |
| IT1295935B1 (it) * | 1997-10-30 | 1999-05-28 | Acs Dobfar Spa | Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici |
| TWI335332B (en) * | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
| CN102015591B (zh) | 2008-03-04 | 2014-01-29 | 艾尼纳制药公司 | 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法 |
| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| KR20180094131A (ko) | 2010-09-01 | 2018-08-22 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신장 손상을 갖는 개체에 대한 로카세린의 투여 |
| CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
| SG188362A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
| WO2014058441A1 (en) | 2012-10-09 | 2014-04-17 | Arena Pharmaceuticals, Inc. | Method of weight management |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5168589A (cg-RX-API-DMAC7.html) * | 1974-12-06 | 1976-06-14 | Shionogi Seiyaku Kk | |
| GB1536281A (en) * | 1975-06-09 | 1978-12-20 | Takeda Chemical Industries Ltd | Cephem compounds |
| DK154939C (da) | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
-
1977
- 1977-12-24 DE DE19772758001 patent/DE2758001A1/de not_active Withdrawn
-
1978
- 1978-12-16 DE DE7878101738T patent/DE2861043D1/de not_active Expired
- 1978-12-16 EP EP78101738A patent/EP0002765B1/de not_active Expired
- 1978-12-19 ES ES476109A patent/ES476109A1/es not_active Expired
- 1978-12-20 EG EG721/78A patent/EG13762A/xx active
- 1978-12-20 US US05/971,558 patent/US4293550A/en not_active Expired - Lifetime
- 1978-12-21 ZA ZA00787209A patent/ZA787209B/xx unknown
- 1978-12-21 FI FI783960A patent/FI66007C/fi not_active IP Right Cessation
- 1978-12-21 PT PT68964A patent/PT68964A/pt unknown
- 1978-12-21 IE IE2546/78A patent/IE48147B1/en unknown
- 1978-12-21 NZ NZ189266A patent/NZ189266A/xx unknown
- 1978-12-22 NO NO784366A patent/NO784366L/no unknown
- 1978-12-22 DK DK578978A patent/DK578978A/da not_active Application Discontinuation
- 1978-12-22 IL IL56284A patent/IL56284A/xx unknown
- 1978-12-22 AU AU42848/78A patent/AU534258B2/en not_active Expired
- 1978-12-22 CA CA318,496A patent/CA1109461A/en not_active Expired
- 1978-12-22 PH PH21988A patent/PH15925A/en unknown
- 1978-12-22 GR GR57978A patent/GR65234B/el unknown
- 1978-12-22 AT AT0924178A patent/AT365599B/de not_active IP Right Cessation
- 1978-12-22 HU HU78HO2127A patent/HU184140B/hu unknown
- 1978-12-23 JP JP15817278A patent/JPS5495592A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IE782546L (en) | 1979-06-24 |
| DE2758001A1 (de) | 1979-07-12 |
| IE48147B1 (en) | 1984-10-17 |
| AT365599B (de) | 1982-01-25 |
| NO784366L (no) | 1979-06-26 |
| HU184140B (en) | 1984-07-30 |
| FI783960A7 (fi) | 1979-06-25 |
| AU534258B2 (en) | 1984-01-12 |
| ZA787209B (en) | 1979-12-27 |
| PH15925A (en) | 1983-04-26 |
| US4293550A (en) | 1981-10-06 |
| JPS5495592A (en) | 1979-07-28 |
| EG13762A (en) | 1982-09-30 |
| NZ189266A (en) | 1981-12-15 |
| AU4284878A (en) | 1979-06-28 |
| EP0002765A1 (de) | 1979-07-11 |
| IL56284A (en) | 1983-03-31 |
| FI66007C (fi) | 1984-08-10 |
| ATA924178A (de) | 1981-06-15 |
| EP0002765B1 (de) | 1981-09-02 |
| GR65234B (en) | 1980-07-30 |
| PT68964A (de) | 1979-01-01 |
| IL56284A0 (en) | 1979-03-12 |
| DK578978A (da) | 1979-06-25 |
| DE2861043D1 (en) | 1981-11-26 |
| CA1109461A (en) | 1981-09-22 |
| FI66007B (fi) | 1984-04-30 |
| JPH0132226B2 (cg-RX-API-DMAC7.html) | 1989-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |