ES471608A1 - Un procedimiento de preparacion de nuevos derivados de piri-midina - Google Patents
Un procedimiento de preparacion de nuevos derivados de piri-midinaInfo
- Publication number
- ES471608A1 ES471608A1 ES471608A ES471608A ES471608A1 ES 471608 A1 ES471608 A1 ES 471608A1 ES 471608 A ES471608 A ES 471608A ES 471608 A ES471608 A ES 471608A ES 471608 A1 ES471608 A1 ES 471608A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- methylpyrimidines
- piperazinyl
- pyridyl
- hydroxymethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Un procedimiento de preparación de nuevos derivados de pirimidina de la fórmula general: **(Fórmula)** en la que R representa un radical piperidino o un radical 4-(2-metil-3-hidroxi-4-hidroximetil-5-piridil-metil)-1-piperazinilo y las sales terapéuticamente aceptables de los mismos, consistente en hacer reaccionar en un disolvente polar, a reflujo, la piperidina o la 4-(2-metil-3-hidroxi-4-hidroximetil-5-piridil-metil)-1-piperazina sobre el cloruro correspondiente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2928177 | 1977-07-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES471608A1 true ES471608A1 (es) | 1979-01-16 |
Family
ID=10289056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES471608A Expired ES471608A1 (es) | 1977-07-12 | 1978-07-11 | Un procedimiento de preparacion de nuevos derivados de piri-midina |
Country Status (28)
Country | Link |
---|---|
US (1) | US4174395A (es) |
JP (1) | JPS5452088A (es) |
AR (1) | AR218072A1 (es) |
AT (1) | AT358198B (es) |
AU (1) | AU517046B2 (es) |
BE (1) | BE868539A (es) |
CA (1) | CA1097645A (es) |
CH (1) | CH632267A5 (es) |
DE (1) | DE2830670C2 (es) |
DK (1) | DK148685C (es) |
EG (1) | EG13550A (es) |
ES (1) | ES471608A1 (es) |
FI (1) | FI63026C (es) |
FR (2) | FR2397413A1 (es) |
HK (1) | HK18783A (es) |
IE (1) | IE47027B1 (es) |
IN (1) | IN148661B (es) |
LU (1) | LU79916A1 (es) |
MX (1) | MX5103E (es) |
MY (1) | MY8500031A (es) |
NL (1) | NL170855C (es) |
NO (1) | NO149846C (es) |
NZ (1) | NZ187655A (es) |
OA (1) | OA06120A (es) |
PT (1) | PT68268A (es) |
SE (1) | SE436875B (es) |
SG (1) | SG60982G (es) |
ZA (1) | ZA783521B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT387221B (de) * | 1980-09-08 | 1988-12-27 | Bristol Myers Co | Verfahren zur herstellung des neuen |
US6854146B2 (en) | 2000-06-12 | 2005-02-15 | Milliken & Company | Method for producing digitally designed carpet |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2459367A (en) * | 1947-11-12 | 1949-01-18 | American Cyanamid Co | 1,4-di (heterocyclic substituted) piperazines |
US2606906A (en) * | 1948-10-14 | 1952-08-12 | American Cyanamid Co | 1-(2-pyridyl) piperazine and process of preparing same |
US2748125A (en) * | 1954-04-26 | 1956-05-29 | American Cyanamid Co | 1-substituted-4-sulfamylpiperazine and method of preparing the same |
GB1433222A (es) * | 1973-03-28 | 1976-04-22 | Prod Ch8Mi Soc Et |
-
1978
- 1978-06-20 ZA ZA00783521A patent/ZA783521B/xx unknown
- 1978-06-21 FI FI781982A patent/FI63026C/fi not_active IP Right Cessation
- 1978-06-21 IN IN457/DEL/78A patent/IN148661B/en unknown
- 1978-06-22 NZ NZ187655A patent/NZ187655A/xx unknown
- 1978-06-28 BE BE188906A patent/BE868539A/xx not_active IP Right Cessation
- 1978-06-29 AT AT474578A patent/AT358198B/de not_active IP Right Cessation
- 1978-07-03 US US05/921,335 patent/US4174395A/en not_active Expired - Lifetime
- 1978-07-04 LU LU79916A patent/LU79916A1/xx unknown
- 1978-07-04 NL NLAANVRAGE7807228,A patent/NL170855C/xx not_active IP Right Cessation
- 1978-07-07 CH CH741778A patent/CH632267A5/fr not_active IP Right Cessation
- 1978-07-10 CA CA307,056A patent/CA1097645A/en not_active Expired
- 1978-07-10 PT PT68268A patent/PT68268A/pt unknown
- 1978-07-10 IE IE1383/78A patent/IE47027B1/en unknown
- 1978-07-11 AU AU37934/78A patent/AU517046B2/en not_active Expired
- 1978-07-11 NO NO782408A patent/NO149846C/no unknown
- 1978-07-11 MX MX787221U patent/MX5103E/es unknown
- 1978-07-11 JP JP8362078A patent/JPS5452088A/ja active Granted
- 1978-07-11 SE SE7807721A patent/SE436875B/sv not_active IP Right Cessation
- 1978-07-11 DK DK310678A patent/DK148685C/da active
- 1978-07-11 EG EG435/78A patent/EG13550A/xx active
- 1978-07-11 ES ES471608A patent/ES471608A1/es not_active Expired
- 1978-07-11 AR AR272915A patent/AR218072A1/es active
- 1978-07-12 FR FR7820755A patent/FR2397413A1/fr active Granted
- 1978-07-12 DE DE2830670A patent/DE2830670C2/de not_active Expired
- 1978-07-12 FR FR7820756A patent/FR2400362A1/fr active Granted
- 1978-09-25 OA OA56615A patent/OA06120A/xx unknown
-
1982
- 1982-12-03 SG SG609/82A patent/SG60982G/en unknown
-
1983
- 1983-06-02 HK HK187/83A patent/HK18783A/xx unknown
-
1985
- 1985-12-30 MY MY31/85A patent/MY8500031A/xx unknown
Also Published As
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