ATE75743T1 - Hydrazinderivate und ihre verwendung. - Google Patents

Hydrazinderivate und ihre verwendung.

Info

Publication number
ATE75743T1
ATE75743T1 AT85112762T AT85112762T ATE75743T1 AT E75743 T1 ATE75743 T1 AT E75743T1 AT 85112762 T AT85112762 T AT 85112762T AT 85112762 T AT85112762 T AT 85112762T AT E75743 T1 ATE75743 T1 AT E75743T1
Authority
AT
Austria
Prior art keywords
hydrazine derivatives
formulaand
exhibited
pharmaceutically acceptable
acceptable salts
Prior art date
Application number
AT85112762T
Other languages
English (en)
Inventor
Uwe Dietmar Treuner
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Application granted granted Critical
Publication of ATE75743T1 publication Critical patent/ATE75743T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
AT85112762T 1984-10-09 1985-10-08 Hydrazinderivate und ihre verwendung. ATE75743T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/658,849 US4610824A (en) 1984-10-09 1984-10-09 Hydrazide derivatives of monocyclic beta-lactam antibiotics
EP85112762A EP0177940B1 (de) 1984-10-09 1985-10-08 Hydrazinderivate und ihre Verwendung

Publications (1)

Publication Number Publication Date
ATE75743T1 true ATE75743T1 (de) 1992-05-15

Family

ID=24642965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85112762T ATE75743T1 (de) 1984-10-09 1985-10-08 Hydrazinderivate und ihre verwendung.

Country Status (5)

Country Link
US (1) US4610824A (de)
EP (1) EP0177940B1 (de)
JP (2) JPH0647588B2 (de)
AT (1) ATE75743T1 (de)
DE (1) DE3585980D1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4632985A (en) * 1985-06-03 1986-12-30 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
US4638062A (en) * 1985-06-17 1987-01-20 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
FI872879A (fi) * 1986-07-21 1988-01-22 Sankei Yakuhin Kk --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes.
US4904775A (en) * 1988-05-16 1990-02-27 E. R. Squibb & Sons, Inc. Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics
CA2024282A1 (en) * 1989-09-21 1991-03-22 Peter H. Ermann Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics
GB8928373D0 (en) * 1989-12-15 1990-02-21 Erba Carlo Spa Beta-lactam derivatives
US5030724A (en) * 1990-01-22 1991-07-09 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
ZA918014B (en) * 1990-11-05 1992-07-29 Squibb & Sons Inc Heteroaroyl derivatives of monocyclic beta-lactam antibiotics
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
DE19625524C2 (de) * 1996-06-26 2000-11-30 Gruenenthal Gmbh Neue synthetische Catechol-Antibiotika-Konjugate und diese enthaltende Arzneimittel
DE19654920A1 (de) 1996-06-26 1998-01-08 Gruenenthal Gmbh Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
BRPI0116757B8 (pt) 2000-12-27 2021-05-25 Corus Pharma Inc composição, formulação e produto contendo aztreonam e uso do mesmo para aplicação via inalatória
SG11201606711UA (en) 2014-03-24 2016-10-28 Novartis Ag Monobactam organic compounds for the treatment of bacterial infections
EP3353175B1 (de) 2015-09-23 2020-08-12 Novartis AG Salze und feste formen eines monobactam-antibiotikums
CN111094281B (zh) 2017-08-02 2023-08-29 诺华股份有限公司 用于制备单内酰胺抗生素的化学方法及其中间体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
NZ196202A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Beta-lactam antibiotics (of azetidine-sulphonic acid type)
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
EP0048953B1 (de) * 1980-09-29 1988-03-09 E.R. Squibb & Sons, Inc. Beta-Lactam-Antibiotika
DE3372768D1 (de) * 1982-06-03 1987-09-03 Hoffmann La Roche 1-sulfo-2-oxoazetidine derivatives

Also Published As

Publication number Publication date
EP0177940B1 (de) 1992-05-06
JPH0647588B2 (ja) 1994-06-22
US4610824A (en) 1986-09-09
EP0177940A3 (en) 1988-03-30
JPS6191187A (ja) 1986-05-09
EP0177940A2 (de) 1986-04-16
DE3585980D1 (de) 1992-06-11
JPH0755938B2 (ja) 1995-06-14
JPH06329648A (ja) 1994-11-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee