DE3585980D1 - Hydrazinderivate und ihre verwendung. - Google Patents
Hydrazinderivate und ihre verwendung.Info
- Publication number
- DE3585980D1 DE3585980D1 DE8585112762T DE3585980T DE3585980D1 DE 3585980 D1 DE3585980 D1 DE 3585980D1 DE 8585112762 T DE8585112762 T DE 8585112762T DE 3585980 T DE3585980 T DE 3585980T DE 3585980 D1 DE3585980 D1 DE 3585980D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrazine derivatives
- formulaand
- exhibited
- pharmaceutically acceptable
- acceptable salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/658,849 US4610824A (en) | 1984-10-09 | 1984-10-09 | Hydrazide derivatives of monocyclic beta-lactam antibiotics |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3585980D1 true DE3585980D1 (de) | 1992-06-11 |
Family
ID=24642965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585112762T Expired - Fee Related DE3585980D1 (de) | 1984-10-09 | 1985-10-08 | Hydrazinderivate und ihre verwendung. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4610824A (de) |
EP (1) | EP0177940B1 (de) |
JP (2) | JPH0647588B2 (de) |
AT (1) | ATE75743T1 (de) |
DE (1) | DE3585980D1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4775670A (en) * | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
US4632985A (en) * | 1985-06-03 | 1986-12-30 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
US4638062A (en) * | 1985-06-17 | 1987-01-20 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
FI872879A (fi) * | 1986-07-21 | 1988-01-22 | Sankei Yakuhin Kk | --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes. |
US4904775A (en) * | 1988-05-16 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics |
CA2024282A1 (en) * | 1989-09-21 | 1991-03-22 | Peter H. Ermann | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics |
GB8928373D0 (en) * | 1989-12-15 | 1990-02-21 | Erba Carlo Spa | Beta-lactam derivatives |
US5030724A (en) * | 1990-01-22 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Monobactam hydrazides containing catechol sulfonic acid groups |
ZA918014B (en) * | 1990-11-05 | 1992-07-29 | Squibb & Sons Inc | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics |
US5250691A (en) * | 1991-09-09 | 1993-10-05 | E. R. Squibb & Sons, Inc. | Heteroaryl derivatives of monocyclic beta-lactam antibiotics |
DE19625524C2 (de) * | 1996-06-26 | 2000-11-30 | Gruenenthal Gmbh | Neue synthetische Catechol-Antibiotika-Konjugate und diese enthaltende Arzneimittel |
DE19654920A1 (de) | 1996-06-26 | 1998-01-08 | Gruenenthal Gmbh | Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
CA2433280C (en) * | 2000-12-27 | 2010-09-21 | Salus Pharma, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
AU2015236369B2 (en) | 2014-03-24 | 2017-02-16 | Novartis Ag | Monobactam organic compounds for the treatment of bacterial infections |
RS60805B1 (sr) | 2015-09-23 | 2020-10-30 | Novartis Ag | Soli i čvrsti oblici monobaktamskog antibiotika |
EP3661933B1 (de) | 2017-08-02 | 2022-03-23 | Novartis AG | Verfahren zur herstellung von 1-(((z)-(1-(2-aminothiazol-4-yl)-2-oxo-2-(((3s,4r)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3- yl)amino)ethylidene)amino)oxy)cyclopropancarbonsäure |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE439312B (sv) * | 1977-03-25 | 1985-06-10 | Roussel Uclaf | Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra |
NZ205240A (en) * | 1980-02-07 | 1984-07-31 | Squibb & Sons Inc | Sulphonamide derivatives,being starting materials for producing beta-lactams |
US4252802A (en) * | 1980-03-13 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins |
EP0048953B1 (de) * | 1980-09-29 | 1988-03-09 | E.R. Squibb & Sons, Inc. | Beta-Lactam-Antibiotika |
EP0096296B1 (de) * | 1982-06-03 | 1987-07-29 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 1-Sulfo-2-oxoazetidinderivate |
-
1984
- 1984-10-09 US US06/658,849 patent/US4610824A/en not_active Expired - Lifetime
-
1985
- 1985-10-08 AT AT85112762T patent/ATE75743T1/de not_active IP Right Cessation
- 1985-10-08 DE DE8585112762T patent/DE3585980D1/de not_active Expired - Fee Related
- 1985-10-08 JP JP60225923A patent/JPH0647588B2/ja not_active Expired - Lifetime
- 1985-10-08 EP EP85112762A patent/EP0177940B1/de not_active Expired - Lifetime
-
1993
- 1993-12-13 JP JP5311610A patent/JPH0755938B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0177940A3 (en) | 1988-03-30 |
ATE75743T1 (de) | 1992-05-15 |
JPS6191187A (ja) | 1986-05-09 |
JPH06329648A (ja) | 1994-11-29 |
US4610824A (en) | 1986-09-09 |
JPH0755938B2 (ja) | 1995-06-14 |
JPH0647588B2 (ja) | 1994-06-22 |
EP0177940B1 (de) | 1992-05-06 |
EP0177940A2 (de) | 1986-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |