NO900795L - Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater. - Google Patents

Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater.

Info

Publication number
NO900795L
NO900795L NO90900795A NO900795A NO900795L NO 900795 L NO900795 L NO 900795L NO 90900795 A NO90900795 A NO 90900795A NO 900795 A NO900795 A NO 900795A NO 900795 L NO900795 L NO 900795L
Authority
NO
Norway
Prior art keywords
phenylycylclanal
piperazinyl
procedure
preparation
new
Prior art date
Application number
NO90900795A
Other languages
English (en)
Other versions
NO900795D0 (no
Inventor
Katsuhiko Hino
Naoki Kai
Masato Sakamoto
Tatsuya Kon
Makoto Oka
Kiyoshi Furukawa
Yoshiaki Ochi
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of NO900795D0 publication Critical patent/NO900795D0/no
Publication of NO900795L publication Critical patent/NO900795L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO90900795A 1989-02-21 1990-02-20 Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater. NO900795L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4072989 1989-02-21

Publications (2)

Publication Number Publication Date
NO900795D0 NO900795D0 (no) 1990-02-20
NO900795L true NO900795L (no) 1990-08-22

Family

ID=12588717

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90900795A NO900795L (no) 1989-02-21 1990-02-20 Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater.

Country Status (9)

Country Link
US (1) US5041443A (no)
EP (2) EP0384228A1 (no)
KR (1) KR910015562A (no)
AU (1) AU622976B2 (no)
CA (1) CA2010477A1 (no)
DD (1) DD297819A5 (no)
FI (1) FI900833A7 (no)
HU (1) HU204815B (no)
NO (1) NO900795L (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174591T1 (de) * 1993-09-15 1999-01-15 Merck Sharp & Dohme Kondensierte tricyclische heteroaromatische derivate als liganden des dopamin-rezeptor- subtyps
MX346801B (es) 2009-03-13 2017-03-31 Agios Pharmaceuticals Inc Métodos y composiciones para trastornos relacionados con la proliferación celular.
CA2944788C (en) 2009-06-29 2023-08-22 Agios Pharmaceuticals, Inc. Compounds, and compositions thereof, which modulate pyruvate kinase m2, and methods of making same
WO2011050210A1 (en) 2009-10-21 2011-04-28 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
EP2525790B1 (en) 2009-10-21 2020-05-27 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
CN103764147B (zh) 2011-05-03 2018-05-22 安吉奥斯医药品有限公司 用于治疗的丙酮酸激酶活化剂
CN102827073A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
CN102827170A (zh) * 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
RS57401B1 (sr) 2012-01-06 2018-09-28 Agios Pharmaceuticals Inc Terapeutski aktivna jedinjenja i postupci za njihovu upotrebu
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
US10202339B2 (en) 2012-10-15 2019-02-12 Agios Pharmaceuticals, Inc. Therapeutic compounds and compositions
WO2015003360A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
AU2014287121B2 (en) 2013-07-11 2018-11-15 Agios Pharmaceuticals, Inc. 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
WO2015003355A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
US20150031627A1 (en) 2013-07-25 2015-01-29 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
KR20220070066A (ko) 2014-03-14 2022-05-27 아지오스 파마슈티컬스 아이엔씨. 치료적으로 활성인 화합물의 약제학적 조성물
PT3307271T (pt) 2015-06-11 2023-10-10 Agios Pharmaceuticals Inc Métodos de utilização de ativadores da piruvato-cinase
DK3362066T3 (da) 2015-10-15 2021-11-22 Les Laboratoires Servier Sas Kombinationsterapi til behandling af maligniteter
AU2016338552B2 (en) 2015-10-15 2022-04-28 Les Laboratoires Servier Combination therapy for treating malignancies
US10980788B2 (en) 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
KR20230158542A (ko) * 2021-03-29 2023-11-20 길리애드 사이언시즈, 인코포레이티드 Khk 억제제

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3915976A (en) * 1972-09-01 1975-10-28 Sandoz Ag Substituted-4-phenyl-5h-cycloalkano(d)pyrimidines
US4133884A (en) * 1977-02-25 1979-01-09 Eli Lilly And Company Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals
EP0022481A1 (en) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions
DE3609596A1 (de) * 1986-03-21 1987-10-01 Hoechst Ag 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
JPS6442472A (en) * 1987-08-10 1989-02-14 Kanebo Ltd Quinazoline derivative, production thereof and brain function disorder improving agent containing said derivative as active ingredient
ATE107922T1 (de) * 1989-03-03 1994-07-15 Dainippon Pharmaceutical Co 2-(1-piperazinyl)-4-phenylcycloalkanpyridin- derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die sie enthalten.

Also Published As

Publication number Publication date
AU4912290A (en) 1990-08-30
HUT53098A (en) 1990-09-28
FI900833A7 (fi) 1990-08-22
HU204815B (en) 1992-02-28
EP0384228A1 (en) 1990-08-29
FI900833A0 (fi) 1990-02-20
CA2010477A1 (en) 1990-08-21
NO900795D0 (no) 1990-02-20
HU900861D0 (en) 1990-05-28
EP0484988A1 (en) 1992-05-13
DD297819A5 (de) 1992-01-23
AU622976B2 (en) 1992-04-30
KR910015562A (ko) 1991-09-30
US5041443A (en) 1991-08-20

Similar Documents

Publication Publication Date Title
NO900795L (no) Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater.
NO905255L (no) Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler.
NO873091L (no) Fremgangsmaate for fremstilling av nye benzimidazolderivater.
NO900934L (no) Fremgangsmaate for fremstilling av nye derivater av 4-substituerte piperaziner.
NO904987L (no) Fremgangsmaate for fremstilling av indolderivater.
NO862427D0 (no) Fremgangsmaate for fremstilling av nye piperazinderivater.
NO905008L (no) Fremgangsmaate for fremstilling av heterocykliske forbindelser.
NO904059D0 (no) Fremgangsmaate for fremstilling av nye substituerte isokinoliner.
NO913612D0 (no) Fremgangsmaate for fremstilling av nye skualen-syntetase-inhibitorer.
NO901813L (no) Fremgangsmaate for fremstilling av nye tieno-triazolo-diazepin-derivater.
NO892543L (no) Fremgangsmaate for fremstilling av nye neplanocinderivater.
NO903431L (no) Fremgangsmaate for fremstilling av kromanderivater.
NO903275D0 (no) Fremgangsmaate for fremstilling av kromanderivater.
NO913391D0 (no) Fremgangsmaate for fremstilling av nye hetrazepinoide syreamider.
NO900074D0 (no) Fremgangsmaate for fremstilling av nye tetralinderivater.
NO903043L (no) Fremgangsmaate for fremstilling av kromanderivater.
NO903207D0 (no) Fremgangsmaate for fremstilling av halogenaminoaromatiske derivater.
NO901102L (no) Fremgangsmaate for fremstilling av nye steroidderivater.
NO904069L (no) Fremgangsmaate for fremstilling av nye alkanofenoner.
NO911118D0 (no) Fremgangsmaate for fremstilling av nye 8-sulfamylmethylen-2-amino-tetraliner.
NO872393L (no) Fremgangsmaate for fremstilling av nye aralkylimidazolderivater.
NO170278C (no) Analogifremgangsmaate for fremstilling av nye antimykotiskvirksomme 2-(tioalkylamino)etyl-1h-imidazolderivater
NO902762D0 (no) Fremgangsmaate for fremstilling av 5-fenyl-2-furan derivater.
NO912979L (no) Fremgangsmaate for fremstilling av 2-(9-fluorenoyl)-carbapenederivater.
NO890644L (no) Fremgangsmaate for fremstilling av nye aspartat-transcarbamylase-inhibitorer.