NO900795L - Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater. - Google Patents
Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater.Info
- Publication number
- NO900795L NO900795L NO90900795A NO900795A NO900795L NO 900795 L NO900795 L NO 900795L NO 90900795 A NO90900795 A NO 90900795A NO 900795 A NO900795 A NO 900795A NO 900795 L NO900795 L NO 900795L
- Authority
- NO
- Norway
- Prior art keywords
- phenylycylclanal
- piperazinyl
- procedure
- preparation
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4072989 | 1989-02-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO900795D0 NO900795D0 (no) | 1990-02-20 |
| NO900795L true NO900795L (no) | 1990-08-22 |
Family
ID=12588717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO90900795A NO900795L (no) | 1989-02-21 | 1990-02-20 | Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5041443A (no) |
| EP (2) | EP0384228A1 (no) |
| KR (1) | KR910015562A (no) |
| AU (1) | AU622976B2 (no) |
| CA (1) | CA2010477A1 (no) |
| DD (1) | DD297819A5 (no) |
| FI (1) | FI900833A7 (no) |
| HU (1) | HU204815B (no) |
| NO (1) | NO900795L (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007893A1 (en) * | 1993-09-15 | 1995-03-23 | Merck Sharp & Dohme Limited | Fused tricyclic heteroaromatic derivatives as dopamine receptor subtype ligands |
| ES2740424T3 (es) | 2009-03-13 | 2020-02-05 | Agios Pharmaceuticals Inc | Métodos y composiciones para trastornos relacionados con la proliferación celular |
| SG10201403696UA (en) | 2009-06-29 | 2014-10-30 | Agios Pharmaceuticals Inc | Therapeutic compounds and compositions |
| EP3064595B1 (en) | 2009-10-21 | 2019-02-27 | Agios Pharmaceuticals, Inc. | Methods for cell-proliferation-related disorders |
| EP2525790B1 (en) | 2009-10-21 | 2020-05-27 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
| JP6272754B2 (ja) | 2011-05-03 | 2018-01-31 | アジオス ファーマシューティカルズ， インコーポレイテッド | ピルビン酸キナーゼ活性化剤の使用方法 |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| LT2800743T (lt) | 2012-01-06 | 2018-06-25 | Agios Pharmaceuticals, Inc. | Terapiškai aktyvūs junginiai ir jų panaudojimo būdai |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| NZ706999A (en) | 2012-10-15 | 2018-12-21 | Agios Pharmaceuticals Inc | Inhibitors of mutant isocitrate dehydrogenase and therapeutical uses thereof |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US10376510B2 (en) | 2013-07-11 | 2019-08-13 | Agios Pharmaceuticals, Inc. | 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer |
| WO2015010297A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US9968595B2 (en) | 2014-03-14 | 2018-05-15 | Agios Pharmaceuticals, Inc. | Pharmaceutical compositions of therapeutically active compounds |
| RS64777B1 (sr) | 2015-06-11 | 2023-11-30 | Agios Pharmaceuticals Inc | Postupci upotrebe aktivatora piruvat kinaze |
| UA123401C2 (uk) | 2015-10-15 | 2021-03-31 | Аджиос Фармасьютікалз, Інк. | Комбінована терапія для лікування злоякісних пухлин |
| DK3362066T3 (da) | 2015-10-15 | 2021-11-22 | Les Laboratoires Servier Sas | Kombinationsterapi til behandling af maligniteter |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| EP4313967B1 (en) * | 2021-03-29 | 2025-11-12 | Gilead Sciences, Inc. | Khk inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3305553A (en) * | 1965-10-18 | 1967-02-21 | Parke Davis & Co | 2-aminoquinazoline derivatives |
| US3915976A (en) * | 1972-09-01 | 1975-10-28 | Sandoz Ag | Substituted-4-phenyl-5h-cycloalkano(d)pyrimidines |
| US4133884A (en) * | 1977-02-25 | 1979-01-09 | Eli Lilly And Company | Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals |
| EP0022481A1 (en) * | 1979-06-21 | 1981-01-21 | Mitsubishi Yuka Pharmaceutical Co., Ltd. | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions |
| DE3609596A1 (de) * | 1986-03-21 | 1987-10-01 | Hoechst Ag | 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| JPS6442472A (en) * | 1987-08-10 | 1989-02-14 | Kanebo Ltd | Quinazoline derivative, production thereof and brain function disorder improving agent containing said derivative as active ingredient |
| DE69010232T2 (de) * | 1989-03-03 | 1994-12-01 | Dainippon Pharmaceutical Co | 2-(1-Piperazinyl)-4-phenylcycloalkanpyridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten. |
-
1990
- 1990-02-01 US US07/473,414 patent/US5041443A/en not_active Expired - Fee Related
- 1990-02-05 AU AU49122/90A patent/AU622976B2/en not_active Ceased
- 1990-02-08 EP EP90102478A patent/EP0384228A1/en not_active Withdrawn
- 1990-02-08 EP EP91122107A patent/EP0484988A1/en not_active Ceased
- 1990-02-19 DD DD90337957A patent/DD297819A5/de not_active IP Right Cessation
- 1990-02-20 HU HU90861A patent/HU204815B/hu not_active IP Right Cessation
- 1990-02-20 CA CA002010477A patent/CA2010477A1/en not_active Abandoned
- 1990-02-20 FI FI900833A patent/FI900833A7/fi not_active IP Right Cessation
- 1990-02-20 NO NO90900795A patent/NO900795L/no unknown
- 1990-02-21 KR KR1019900002231A patent/KR910015562A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0384228A1 (en) | 1990-08-29 |
| DD297819A5 (de) | 1992-01-23 |
| AU4912290A (en) | 1990-08-30 |
| FI900833A0 (fi) | 1990-02-20 |
| AU622976B2 (en) | 1992-04-30 |
| KR910015562A (ko) | 1991-09-30 |
| US5041443A (en) | 1991-08-20 |
| NO900795D0 (no) | 1990-02-20 |
| FI900833A7 (fi) | 1990-08-22 |
| CA2010477A1 (en) | 1990-08-21 |
| HUT53098A (en) | 1990-09-28 |
| EP0484988A1 (en) | 1992-05-13 |
| HU204815B (en) | 1992-02-28 |
| HU900861D0 (en) | 1990-05-28 |
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