NO900934L - Fremgangsmaate for fremstilling av nye derivater av 4-substituerte piperaziner. - Google Patents
Fremgangsmaate for fremstilling av nye derivater av 4-substituerte piperaziner.Info
- Publication number
- NO900934L NO900934L NO90900934A NO900934A NO900934L NO 900934 L NO900934 L NO 900934L NO 90900934 A NO90900934 A NO 90900934A NO 900934 A NO900934 A NO 900934A NO 900934 L NO900934 L NO 900934L
- Authority
- NO
- Norway
- Prior art keywords
- procedure
- preparation
- new derivatives
- substituted piperazines
- piperazines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89500021A EP0385043A1 (en) | 1989-02-28 | 1989-02-28 | New derivatives of 4-substituted piperazines |
Publications (2)
Publication Number | Publication Date |
---|---|
NO900934D0 NO900934D0 (no) | 1990-02-27 |
NO900934L true NO900934L (no) | 1990-08-29 |
Family
ID=8203081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO90900934A NO900934L (no) | 1989-02-28 | 1990-02-27 | Fremgangsmaate for fremstilling av nye derivater av 4-substituerte piperaziner. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5011928A (no) |
EP (1) | EP0385043A1 (no) |
JP (1) | JPH02288861A (no) |
AU (1) | AU636132B2 (no) |
CA (1) | CA2010750A1 (no) |
FI (1) | FI900963A0 (no) |
NO (1) | NO900934L (no) |
PE (1) | PE13391A1 (no) |
PT (1) | PT93276A (no) |
ZA (1) | ZA901449B (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5281623A (en) * | 1990-08-27 | 1994-01-25 | Eli Lilly And Company | Method for treating inflammation |
ZA916555B (en) * | 1990-08-27 | 1993-04-28 | Lilly Co Eli | Method of treating inflammatory bowel disease |
EP0489690A1 (de) * | 1990-12-05 | 1992-06-10 | Ciba-Geigy Ag | Substituierte N-Benzoyl-N'-(2-phenylethyl)-piperazine |
ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
US5280046A (en) * | 1991-02-22 | 1994-01-18 | The University Of Colorado Foundation, Inc. | Method of treating type I diabetes |
EP0524146A1 (de) * | 1991-07-19 | 1993-01-20 | Ciba-Geigy Ag | Aminosubstituierte Piperazinderivate |
FR2680508B1 (fr) * | 1991-08-20 | 1995-03-03 | Adir | Nouveaux composes amidiques des 1-(alcoxybenzyl)piperazines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
US5830854A (en) * | 1992-12-14 | 1998-11-03 | Merck Sharp & Dohme, Limited | Method of treating cystic fibrosis using a tachykinin receptor antagonist |
US5384319A (en) * | 1993-01-06 | 1995-01-24 | Ciba-Geigy Corporation | Aminoalkylphenyl compounds |
US5380726A (en) * | 1993-01-15 | 1995-01-10 | Ciba-Geigy Corporation | Substituted dialkylthio ethers |
KR100342947B1 (ko) * | 1997-04-30 | 2002-08-22 | 주식회사 엘지씨아이 | 제초활성 아릴피페라진아미드 유도체 |
US6399618B1 (en) | 1997-07-09 | 2002-06-04 | Cardiome Pharma Corp | Compositions and methods for modulating sexual activity |
US6136807A (en) * | 1998-11-10 | 2000-10-24 | 3M Innovative Properties Company | Composition for the transdermal delivery of lerisetron |
DE60234453D1 (de) * | 2001-07-02 | 2009-12-31 | High Point Pharmaceuticals Llc | Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren |
US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
DE60328690D1 (de) * | 2002-06-12 | 2009-09-17 | Chemocentryx Inc | 1-aryl-4-substituierte piperazin-derivate zur verwendung als ccr1-antagonisten zur behandlung von entzündungen und immunerkrankungen |
US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
WO2004002965A1 (de) * | 2002-06-29 | 2004-01-08 | Zentaris Gmbh | Aryl- und heteroarylcarbonylpiperazine und deren verwendung zur behandlung gutartiger und bösartiger tumorerkrankungen |
WO2005084667A1 (en) * | 2004-03-03 | 2005-09-15 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
RS59411B1 (sr) | 2013-03-13 | 2019-11-29 | Forma Therapeutics Inc | Derivati 2-hidroksi-1-{4-[(4-fenilfenil)karbonil]piperazin-1-il}etan-1-ona i srodna jedinjenja kao inhibitori sintaze masnih kiselina (fasn) za lečenje kancera |
WO2020092395A1 (en) | 2018-10-29 | 2020-05-07 | Forma Therapeutics, Inc. | SOLID FORMS OF (4-(2-FLUORO-4-(1-METHYL-1 H-BENZO[d]IMIDAZOL-5-YL)BENZOYL) PIPERAZIN-1-YL)(1-HYDROXYCYCLOPROPYL)METHANONE |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE791501A (fr) * | 1971-11-19 | 1973-05-17 | Albert Ag Chem Werke | Diamines cycliques n,n'-disubstituees et leur procede de preparation |
JPS5346988A (en) * | 1976-10-07 | 1978-04-27 | Kyorin Seiyaku Kk | Piperadine derivative |
DE3139970A1 (de) * | 1981-10-08 | 1983-04-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US4624953A (en) * | 1981-12-02 | 1986-11-25 | Bjoerk Anders K | 1-piperazinocarboxylates and pharmaceutical compositions containing them |
AU545463B2 (en) * | 1982-06-25 | 1985-07-18 | Kowa Co. Ltd. | Benzoyl piperacine esters |
US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
DE3602243A1 (de) * | 1985-06-13 | 1986-12-18 | Bayer Ag, 5090 Leverkusen | E-isomere von n(pfeil hoch)(alpha)(pfeil hoch)-(2-cyan-2-alkoximino-acetyl)-aminosaeurederivaten und -peptiden |
MY102447A (en) * | 1986-06-16 | 1992-06-30 | Ciba Geigy Ag | Disubtituted piperazines |
-
1989
- 1989-02-28 EP EP89500021A patent/EP0385043A1/en not_active Withdrawn
-
1990
- 1990-02-22 CA CA002010750A patent/CA2010750A1/en not_active Abandoned
- 1990-02-23 PE PE1990165681A patent/PE13391A1/es unknown
- 1990-02-26 FI FI900963A patent/FI900963A0/fi not_active IP Right Cessation
- 1990-02-26 ZA ZA901449A patent/ZA901449B/xx unknown
- 1990-02-27 NO NO90900934A patent/NO900934L/no unknown
- 1990-02-27 AU AU50166/90A patent/AU636132B2/en not_active Ceased
- 1990-02-28 US US07/486,098 patent/US5011928A/en not_active Expired - Fee Related
- 1990-02-28 PT PT93276A patent/PT93276A/pt not_active Application Discontinuation
- 1990-02-28 JP JP2049107A patent/JPH02288861A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA901449B (en) | 1991-03-27 |
AU5016690A (en) | 1990-09-06 |
EP0385043A1 (en) | 1990-09-05 |
PE13391A1 (es) | 1991-04-17 |
FI900963A0 (fi) | 1990-02-26 |
NO900934D0 (no) | 1990-02-27 |
PT93276A (pt) | 1990-08-31 |
JPH02288861A (ja) | 1990-11-28 |
AU636132B2 (en) | 1993-04-22 |
CA2010750A1 (en) | 1990-08-31 |
US5011928A (en) | 1991-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO900934L (no) | Fremgangsmaate for fremstilling av nye derivater av 4-substituerte piperaziner. | |
NO873091L (no) | Fremgangsmaate for fremstilling av nye benzimidazolderivater. | |
NO862427L (no) | Fremgangsmaate for fremstilling av nye piperazinderivater. | |
NO905255D0 (no) | Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler. | |
NO871727D0 (no) | Fremgangsmaate for fremstilling av nye kinolinderivater. | |
NO900795D0 (no) | Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkan-pyrimidinderivater. | |
NO880452L (no) | Fremgangsmaate for fremstilling av nye polyaminderivater. | |
NO904059D0 (no) | Fremgangsmaate for fremstilling av nye substituerte isokinoliner. | |
NO902776L (no) | Fremgangsmaate for fremstilling av nye acetylcholinesterase-inhibitorer. | |
NO892543L (no) | Fremgangsmaate for fremstilling av nye neplanocinderivater. | |
NO901813D0 (no) | Fremgangsmaate for fremstilling av nye tieno-triazolo-diazepin-derivater. | |
NO913391D0 (no) | Fremgangsmaate for fremstilling av nye hetrazepinoide syreamider. | |
NO900074L (no) | Fremgangsmaate for fremstilling av nye tetralinderivater. | |
NO892977D0 (no) | Fremgangsmaate for fremstilling av nye s-adenosylmethionin-derivater. | |
NO901102D0 (no) | Fremgangsmaate for fremstilling av nye steroidderivater. | |
NO904069L (no) | Fremgangsmaate for fremstilling av nye alkanofenoner. | |
NO911118L (no) | Fremgangsmaate for fremstilling av nye 8-sulfamylmethylen-2-amino-tetraliner. | |
NO891381D0 (no) | Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater. | |
NO872393D0 (no) | Fremgangsmaate for fremstilling av nye aralkylimidazolderivater. | |
NO854577L (no) | Fremgangsmaate for fremstilling av nye tienopyridinderivater. | |
NO169590C (no) | Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive sialosylglycerider | |
NO890644D0 (no) | Fremgangsmaate for fremstilling av nye aspartat-transcarbamylase-inhibitorer. | |
NO871721L (no) | Fremgangsmaate for fremstilling av nye ergolenderivater. | |
NO902293L (no) | Fremgangsmaate for fremstilling av nye tiazepinderivater. | |
NO851868L (no) | Fremgangsmaate for fremstilling av nye kinolinderivater. |