ES458093A1 - Method of preparing n-glycosyl derivatives of polyene macrolide and the salts thereof - Google Patents
Method of preparing n-glycosyl derivatives of polyene macrolide and the salts thereofInfo
- Publication number
- ES458093A1 ES458093A1 ES458093A ES458093A ES458093A1 ES 458093 A1 ES458093 A1 ES 458093A1 ES 458093 A ES458093 A ES 458093A ES 458093 A ES458093 A ES 458093A ES 458093 A1 ES458093 A1 ES 458093A1
- Authority
- ES
- Spain
- Prior art keywords
- polyene macrolide
- salts
- preparing
- glycosyl derivatives
- organic solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL1976188979A PL100966B1 (en) | 1976-04-22 | 1976-04-22 | METHOD OF OBTAINING N-GLYCOSYL DERIVATIVES OF POLYENUM MACROLIDES AND THEIR SALT, ESPECIALLY N-METHYL GLUCAMINE SALT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES458093A1 true ES458093A1 (en) | 1978-03-16 |
Family
ID=19976536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES458093A Expired ES458093A1 (en) | 1976-04-22 | 1977-04-22 | Method of preparing n-glycosyl derivatives of polyene macrolide and the salts thereof |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS52131594A (en) |
| AU (1) | AU513015B2 (en) |
| BE (1) | BE853893A (en) |
| BR (1) | BR7702505A (en) |
| CA (1) | CA1072088A (en) |
| CH (1) | CH631995A5 (en) |
| CS (1) | CS193092B2 (en) |
| DD (1) | DD129331A5 (en) |
| DE (1) | DE2717811C2 (en) |
| DK (1) | DK178077A (en) |
| ES (1) | ES458093A1 (en) |
| FR (1) | FR2361418A1 (en) |
| GB (1) | GB1582378A (en) |
| HU (1) | HU177885B (en) |
| IN (1) | IN144113B (en) |
| IT (1) | IT1080375B (en) |
| NL (1) | NL7704395A (en) |
| PL (1) | PL100966B1 (en) |
| RO (1) | RO71938A (en) |
| SE (1) | SE7704604L (en) |
| YU (1) | YU96677A (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL122086B1 (en) * | 1979-04-09 | 1982-06-30 | Politechnika Gdanska | Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh |
| GB2122892B (en) * | 1982-07-02 | 1986-01-29 | Squibb & Sons Inc | Nystantin pastille formulation |
| US9447136B2 (en) | 2012-03-09 | 2016-09-20 | Blirt S.A. | Semisynthetic derivatives of Nystatin A1 |
| BR112014031060A2 (en) | 2012-06-15 | 2017-06-27 | Blirt S A | compound of formula 1a; pharmaceutical composition; use of the compound; method for treating fungal infection in a patient; plant protection product; method for treating fungal infection in a plant; antifungal building treatment product; method for treating a building; and compound for use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI60877C (en) * | 1971-08-13 | 1982-04-13 | Politechnika Gdanska | PROTECTION OF THERAPEUTIC ACTIVITIES OF THERAPEUTIC ACTIVITIES WITH A DISPENSABLE POLYENMACROLIDANTIBIOTICS-N-GLYCOSYL DERIVATIVES |
| DE2417993C2 (en) * | 1974-04-11 | 1982-07-01 | Leningradskij naučno-issledovatel'skij institut antibiotikov, Leningrad | Polyene macrolide antibiotic complexes, processes for their preparation and pharmaceuticals containing these compounds |
-
1976
- 1976-04-22 PL PL1976188979A patent/PL100966B1/en unknown
-
1977
- 1977-04-06 CH CH433677A patent/CH631995A5/en not_active IP Right Cessation
- 1977-04-12 YU YU00966/77A patent/YU96677A/en unknown
- 1977-04-12 IN IN557/CAL/1977A patent/IN144113B/en unknown
- 1977-04-12 GB GB15058/77A patent/GB1582378A/en not_active Expired
- 1977-04-19 AU AU24418/77A patent/AU513015B2/en not_active Expired
- 1977-04-20 RO RO7790105A patent/RO71938A/en unknown
- 1977-04-20 DD DD7700198505A patent/DD129331A5/en unknown
- 1977-04-20 FR FR7711907A patent/FR2361418A1/en active Granted
- 1977-04-21 SE SE7704604A patent/SE7704604L/en not_active Application Discontinuation
- 1977-04-21 CS CS772666A patent/CS193092B2/en unknown
- 1977-04-21 DE DE2717811A patent/DE2717811C2/en not_active Expired
- 1977-04-21 IT IT22707/77A patent/IT1080375B/en active
- 1977-04-21 CA CA276,646A patent/CA1072088A/en not_active Expired
- 1977-04-22 ES ES458093A patent/ES458093A1/en not_active Expired
- 1977-04-22 DK DK178077A patent/DK178077A/en unknown
- 1977-04-22 JP JP4671377A patent/JPS52131594A/en active Granted
- 1977-04-22 HU HU77PO646A patent/HU177885B/en unknown
- 1977-04-22 NL NL7704395A patent/NL7704395A/en not_active Application Discontinuation
- 1977-04-22 BE BE176963A patent/BE853893A/en unknown
- 1977-05-27 BR BR7702505A patent/BR7702505A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH631995A5 (en) | 1982-09-15 |
| BR7702505A (en) | 1978-03-21 |
| DD129331A5 (en) | 1978-01-11 |
| PL100966B1 (en) | 1978-11-30 |
| JPS5721278B2 (en) | 1982-05-06 |
| YU96677A (en) | 1982-06-30 |
| HU177885B (en) | 1982-01-28 |
| IN144113B (en) | 1978-03-25 |
| AU2441877A (en) | 1978-10-26 |
| RO71938A (en) | 1981-11-04 |
| NL7704395A (en) | 1977-10-25 |
| DE2717811A1 (en) | 1977-10-27 |
| JPS52131594A (en) | 1977-11-04 |
| BE853893A (en) | 1977-08-16 |
| GB1582378A (en) | 1981-01-07 |
| DK178077A (en) | 1977-10-23 |
| CS193092B2 (en) | 1979-09-17 |
| DE2717811C2 (en) | 1983-10-20 |
| FR2361418A1 (en) | 1978-03-10 |
| CA1072088A (en) | 1980-02-19 |
| SE7704604L (en) | 1977-10-23 |
| FR2361418B1 (en) | 1980-04-18 |
| AU513015B2 (en) | 1980-11-06 |
| IT1080375B (en) | 1985-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1095833A (en) | Desacylated polynuclear indoles | |
| GB1112211A (en) | Derivatives of the antibiotic tylosin | |
| ES458093A1 (en) | Method of preparing n-glycosyl derivatives of polyene macrolide and the salts thereof | |
| GB985162A (en) | Derivatives of the antibiotic decoyinine | |
| GB1044956A (en) | Process for the manufacture of polymers of open chain n-vinyl amides | |
| GB1182513A (en) | Guanosine Derivatives and a process for preparing the same | |
| Jones et al. | THE PREPARATION OF l-SORBOSE FROM 5-KETO-d-GLUCONIC ACID (l-SORBURONIC ACID) | |
| FR83479E (en) | Process for preparing barium hydroxide | |
| FR2183710A1 (en) | Daunomycin (hydrochloride) prepn - by reaction of daunomycinone with daunosamines, useful as antitumour agent and anti-leucemic | |
| NL6701356A (en) | ||
| ES361544A1 (en) | Process for the production of a new antibiotic sf-733 substance | |
| GB1075286A (en) | Process for producing potassium azide | |
| ES386223A1 (en) | Procedure for the preparation of salts from the escina. (Machine-translation by Google Translate, not legally binding) | |
| GB1191493A (en) | Method for preparing Methylene Bis (Thiocyanate) | |
| GB1155310A (en) | Process for Increasing the Yield of Tylosin Produced by Fermentation of Microorganisms. | |
| GB1118942A (en) | A process for obtaining purified glutamic acid | |
| GB1021112A (en) | A new salt and a new process for the recovery of kanamycin | |
| GB787056A (en) | Improvements relating to the production of tetracycline by the hydrogenolysis of chlortetracycline | |
| GB930302A (en) | A process for preparing thiamine derivatives | |
| GB938478A (en) | New antibioticsí¬zygomycin a and zygomycin b | |
| ES408008A2 (en) | Procedure for the preparation of 2- (furilmetil) -6,7-benzomorphanes. (Machine-translation by Google Translate, not legally binding) | |
| JPS6420093A (en) | Production of n-acetylkitooligosaccharide derivative | |
| GB1007800A (en) | New antibiotic | |
| GB959734A (en) | Improvements in or relating to the preparation of monosodium novobiocin | |
| GB775946A (en) | O-carbamyl-d-serine and process for its production |