SE7704604L - METHODS OF PREPARING N-GLYCOSYL DERIVATIVES OF POLYENE MACROLIDES AND SALTS THEREOF, IN PARTICULAR N-METHYL GLUCAMINE SALT - Google Patents

METHODS OF PREPARING N-GLYCOSYL DERIVATIVES OF POLYENE MACROLIDES AND SALTS THEREOF, IN PARTICULAR N-METHYL GLUCAMINE SALT

Info

Publication number
SE7704604L
SE7704604L SE7704604A SE7704604A SE7704604L SE 7704604 L SE7704604 L SE 7704604L SE 7704604 A SE7704604 A SE 7704604A SE 7704604 A SE7704604 A SE 7704604A SE 7704604 L SE7704604 L SE 7704604L
Authority
SE
Sweden
Prior art keywords
salts
preparing
methods
glucamine salt
methyl glucamine
Prior art date
Application number
SE7704604A
Other languages
Swedish (sv)
Inventor
L Falkowski
Z Kowszyk-Gindifer
Z Plociennik
J Zielinski
H Dahlig
J Golik
E Jakobs
P Kolodziejczyk
E Bylec
D Roslik-Kaminska
W Wagner
J Pawlak
E Borowski
Original Assignee
Politechnika Gdanska
Inst Przemyslu Farmaceutic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Gdanska, Inst Przemyslu Farmaceutic filed Critical Politechnika Gdanska
Publication of SE7704604L publication Critical patent/SE7704604L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.
SE7704604A 1976-04-22 1977-04-21 METHODS OF PREPARING N-GLYCOSYL DERIVATIVES OF POLYENE MACROLIDES AND SALTS THEREOF, IN PARTICULAR N-METHYL GLUCAMINE SALT SE7704604L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1976188979A PL100966B1 (en) 1976-04-22 1976-04-22 METHOD OF OBTAINING N-GLYCOSYL DERIVATIVES OF POLYENUM MACROLIDES AND THEIR SALT, ESPECIALLY N-METHYL GLUCAMINE SALT

Publications (1)

Publication Number Publication Date
SE7704604L true SE7704604L (en) 1977-10-23

Family

ID=19976536

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7704604A SE7704604L (en) 1976-04-22 1977-04-21 METHODS OF PREPARING N-GLYCOSYL DERIVATIVES OF POLYENE MACROLIDES AND SALTS THEREOF, IN PARTICULAR N-METHYL GLUCAMINE SALT

Country Status (21)

Country Link
JP (1) JPS52131594A (en)
AU (1) AU513015B2 (en)
BE (1) BE853893A (en)
BR (1) BR7702505A (en)
CA (1) CA1072088A (en)
CH (1) CH631995A5 (en)
CS (1) CS193092B2 (en)
DD (1) DD129331A5 (en)
DE (1) DE2717811C2 (en)
DK (1) DK178077A (en)
ES (1) ES458093A1 (en)
FR (1) FR2361418A1 (en)
GB (1) GB1582378A (en)
HU (1) HU177885B (en)
IN (1) IN144113B (en)
IT (1) IT1080375B (en)
NL (1) NL7704395A (en)
PL (1) PL100966B1 (en)
RO (1) RO71938A (en)
SE (1) SE7704604L (en)
YU (1) YU96677A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122086B1 (en) * 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
GB2122892B (en) * 1982-07-02 1986-01-29 Squibb & Sons Inc Nystantin pastille formulation
US9447136B2 (en) 2012-03-09 2016-09-20 Blirt S.A. Semisynthetic derivatives of Nystatin A1
BR112014031060A2 (en) 2012-06-15 2017-06-27 Blirt S A compound of formula 1a; pharmaceutical composition; use of the compound; method for treating fungal infection in a patient; plant protection product; method for treating fungal infection in a plant; antifungal building treatment product; method for treating a building; and compound for use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (en) * 1971-08-13 1982-04-13 Politechnika Gdanska PROTECTION OF THERAPEUTIC ACTIVITIES OF THERAPEUTIC ACTIVITIES WITH A DISPENSABLE POLYENMACROLIDANTIBIOTICS-N-GLYCOSYL DERIVATIVES
DE2417993C2 (en) * 1974-04-11 1982-07-01 Leningradskij naučno-issledovatel'skij institut antibiotikov, Leningrad Polyene macrolide antibiotic complexes, processes for their preparation and pharmaceuticals containing these compounds

Also Published As

Publication number Publication date
CH631995A5 (en) 1982-09-15
BR7702505A (en) 1978-03-21
DD129331A5 (en) 1978-01-11
ES458093A1 (en) 1978-03-16
PL100966B1 (en) 1978-11-30
JPS5721278B2 (en) 1982-05-06
YU96677A (en) 1982-06-30
HU177885B (en) 1982-01-28
IN144113B (en) 1978-03-25
AU2441877A (en) 1978-10-26
RO71938A (en) 1981-11-04
NL7704395A (en) 1977-10-25
DE2717811A1 (en) 1977-10-27
JPS52131594A (en) 1977-11-04
BE853893A (en) 1977-08-16
GB1582378A (en) 1981-01-07
DK178077A (en) 1977-10-23
CS193092B2 (en) 1979-09-17
DE2717811C2 (en) 1983-10-20
FR2361418A1 (en) 1978-03-10
CA1072088A (en) 1980-02-19
FR2361418B1 (en) 1980-04-18
AU513015B2 (en) 1980-11-06
IT1080375B (en) 1985-05-16

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