ES456963A1 - Procedimiento para preparar derivados carbostirilo. - Google Patents
Procedimiento para preparar derivados carbostirilo.Info
- Publication number
- ES456963A1 ES456963A1 ES456963A ES456963A ES456963A1 ES 456963 A1 ES456963 A1 ES 456963A1 ES 456963 A ES456963 A ES 456963A ES 456963 A ES456963 A ES 456963A ES 456963 A1 ES456963 A1 ES 456963A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen atom
- phenylalkyl
- carbostyril
- alkoxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
- 125000005093 alkyl carbonyl alkyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005242 carbamoyl alkyl group Chemical group 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000005359 phenoxyalkyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51028957A JPS5919541B2 (ja) | 1976-03-17 | 1976-03-17 | 新規３，４−ジヒドロカルボスチリル誘導体 |
| JP51052498A JPS609501B2 (ja) | 1976-05-07 | 1976-05-07 | 新規３，４−ジヒドロカルボスチリル誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456963A1 true ES456963A1 (es) | 1978-07-16 |
Family
ID=26367107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456963A Expired ES456963A1 (es) | 1976-03-17 | 1977-03-17 | Procedimiento para preparar derivados carbostirilo. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4289883A (en, 2012) |
| AR (1) | AR211570A1 (en, 2012) |
| AT (1) | AT363474B (en, 2012) |
| AU (1) | AU513950B2 (en, 2012) |
| CA (1) | CA1081232A (en, 2012) |
| CH (1) | CH619453A5 (en, 2012) |
| DE (1) | DE2711719C2 (en, 2012) |
| DK (1) | DK154970C (en, 2012) |
| ES (1) | ES456963A1 (en, 2012) |
| FI (1) | FI63224C (en, 2012) |
| FR (1) | FR2344538A1 (en, 2012) |
| GB (2) | GB1578972A (en, 2012) |
| IE (1) | IE45269B1 (en, 2012) |
| LU (1) | LU76957A1 (en, 2012) |
| MX (1) | MX4808E (en, 2012) |
| NL (1) | NL179816C (en, 2012) |
| NO (1) | NO149388C (en, 2012) |
| PH (1) | PH15115A (en, 2012) |
| PT (1) | PT66312B (en, 2012) |
| SE (1) | SE443140B (en, 2012) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| DE2901336A1 (de) * | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| AU518814B2 (en) * | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
| DE3034237A1 (de) * | 1979-09-18 | 1981-04-16 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel |
| FR2539413A1 (fr) * | 1983-01-17 | 1984-07-20 | Pos Lab | Carbostyriloximinopropanolamines utiles comme medicaments et procede pour leur preparation |
| US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
| NZ332068A (en) * | 1996-04-09 | 2001-03-30 | Smithkline Beecham | Alpha, alpha-disubstituted arylalkylamine derivatives as calcilytic compounds |
| US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
| US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
| TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910924A (en) * | 1972-04-13 | 1975-10-07 | Otsuka Pharma Co Ltd | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
| JPS48103590A (en, 2012) * | 1972-04-13 | 1973-12-25 | ||
| JPS5239035B2 (en, 2012) * | 1972-12-14 | 1977-10-03 | ||
| US3975391A (en) * | 1973-12-26 | 1976-08-17 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
| JPS5082218A (en, 2012) * | 1973-11-10 | 1975-07-03 | ||
| DK138890C (da) * | 1973-12-26 | 1979-04-30 | Otsuka Pharma Co Ltd | Analogifremgangsmaade til fremstilling af et carbostyril- eller 3,4-dihydrocarbostyrilderivat eller syreadditionssalte deraf |
| US4026897A (en) * | 1974-01-31 | 1977-05-31 | Otsuka Pharmaceutical Company | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives |
| US3994901A (en) * | 1974-06-13 | 1976-11-30 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
| FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
| US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
| US4210753A (en) * | 1976-03-17 | 1980-07-01 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds |
-
1977
- 1977-03-11 CH CH308777A patent/CH619453A5/fr not_active IP Right Cessation
- 1977-03-15 FI FI770827A patent/FI63224C/fi not_active IP Right Cessation
- 1977-03-15 IE IE563/77A patent/IE45269B1/en not_active IP Right Cessation
- 1977-03-16 LU LU76957A patent/LU76957A1/xx unknown
- 1977-03-16 NO NO770940A patent/NO149388C/no unknown
- 1977-03-16 MX MX775546U patent/MX4808E/es unknown
- 1977-03-16 DK DK115677A patent/DK154970C/da not_active IP Right Cessation
- 1977-03-16 SE SE7703000A patent/SE443140B/xx not_active IP Right Cessation
- 1977-03-16 PT PT66312A patent/PT66312B/pt unknown
- 1977-03-16 AU AU23299/77A patent/AU513950B2/en not_active Expired
- 1977-03-17 NL NLAANVRAGE7702896,A patent/NL179816C/xx not_active IP Right Cessation
- 1977-03-17 GB GB27038/79A patent/GB1578972A/en not_active Expired
- 1977-03-17 PH PH19562A patent/PH15115A/en unknown
- 1977-03-17 AT AT0181577A patent/AT363474B/de active
- 1977-03-17 AR AR266891A patent/AR211570A1/es active
- 1977-03-17 FR FR7708041A patent/FR2344538A1/fr active Granted
- 1977-03-17 CA CA274,453A patent/CA1081232A/en not_active Expired
- 1977-03-17 ES ES456963A patent/ES456963A1/es not_active Expired
- 1977-03-17 DE DE2711719A patent/DE2711719C2/de not_active Expired
- 1977-03-17 GB GB11461/77A patent/GB1578971A/en not_active Expired
-
1978
- 1978-11-30 US US05/965,535 patent/US4289883A/en not_active Expired - Lifetime
- 1978-11-30 US US05/965,469 patent/US4302588A/en not_active Expired - Lifetime
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