ES449748A1 - Procedimiento para la preparacion de escina roentgenamorfa. - Google Patents
Procedimiento para la preparacion de escina roentgenamorfa.Info
- Publication number
- ES449748A1 ES449748A1 ES449748A ES449748A ES449748A1 ES 449748 A1 ES449748 A1 ES 449748A1 ES 449748 A ES449748 A ES 449748A ES 449748 A ES449748 A ES 449748A ES 449748 A1 ES449748 A1 ES 449748A1
- Authority
- ES
- Spain
- Prior art keywords
- escin
- roentgenamorphic
- aescin
- amorphous
- crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YFESOSRPNPYODN-RSMWSHJLSA-N (2s,3s,4s,5r,6r)-6-[[(4s,6ar,6bs,8r,8ar,9r,10r,14br)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2s,3r,4s, Chemical compound O([C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)OC1CC[C@]2(C)C3CC=C4[C@@]([C@@]3(CCC2[C@]1(CO)C)C)(C)C[C@@H](O)[C@@]1(CO)[C@@H](OC(C)=O)[C@@H](C(CC14)(C)C)OC(=O)C(\C)=C/C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O([C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)OC1CC[C@]2(C)C3CC=C4[C@@]([C@@]3(CCC2[C@]1(CO)C)C)(C)C[C@@H](O)[C@@]1(CO)[C@@H](OC(C)=O)[C@@H](C(CC14)(C)C)OC(=O)C(/C)=C/C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YFESOSRPNPYODN-RSMWSHJLSA-N 0.000 title 1
- 229940011399 escin Drugs 0.000 abstract 4
- 229930186222 escin Natural products 0.000 abstract 4
- 125000005233 alkylalcohol group Chemical group 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000011261 inert gas Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2530953A DE2530953C2 (de) | 1975-07-11 | 1975-07-11 | Verfahren zur Herstellung von röntgenamorphem Aescin, nach diesem Verfahren erhältliches röntgenamorphes Aescin und dieses enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449748A1 true ES449748A1 (es) | 1977-08-16 |
Family
ID=5951225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449748A Expired ES449748A1 (es) | 1975-07-11 | 1976-07-10 | Procedimiento para la preparacion de escina roentgenamorfa. |
Country Status (20)
| Country | Link |
|---|---|
| JP (2) | JPS5234915A (cs) |
| AU (1) | AU510463B2 (cs) |
| BE (1) | BE844053A (cs) |
| BG (1) | BG27379A3 (cs) |
| CA (1) | CA1064903A (cs) |
| CS (1) | CS208184B2 (cs) |
| DE (1) | DE2530953C2 (cs) |
| ES (1) | ES449748A1 (cs) |
| FI (1) | FI62099C (cs) |
| FR (1) | FR2316961A1 (cs) |
| GB (1) | GB1550845A (cs) |
| HK (1) | HK33681A (cs) |
| HU (1) | HU174603B (cs) |
| PH (1) | PH13989A (cs) |
| PL (1) | PL99028B1 (cs) |
| PT (1) | PT65302B (cs) |
| RO (1) | RO70354A (cs) |
| SU (1) | SU786857A3 (cs) |
| YU (1) | YU41812B (cs) |
| ZA (1) | ZA764065B (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1252201B (it) * | 1991-12-12 | 1995-06-05 | Dompe Farmaceutici Spa | S-carbossimetilcisteina sale di lisina monoidrato e procedimento per la sua preparazione. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE302543C (cs) * | ||||
| NL301747A (cs) * | 1962-12-14 | |||
| YU37063B (en) * | 1971-12-06 | 1984-08-31 | Lek Tovarna Farmacevtskih | Process for preparing x-ray amorphous water-sulubleascin |
| DE2357226A1 (de) * | 1973-11-16 | 1975-05-28 | Merck Patent Gmbh | Verfahren zur herstellung von wasserloeslichem beta-aescin |
-
1975
- 1975-07-11 DE DE2530953A patent/DE2530953C2/de not_active Expired - Lifetime
-
1976
- 1976-06-30 FI FI761895A patent/FI62099C/fi not_active IP Right Cessation
- 1976-06-30 PT PT65302A patent/PT65302B/pt unknown
- 1976-07-05 BG BG033673A patent/BG27379A3/xx unknown
- 1976-07-07 SU SU762377645A patent/SU786857A3/ru active
- 1976-07-07 GB GB28233/76A patent/GB1550845A/en not_active Expired
- 1976-07-08 AU AU15729/76A patent/AU510463B2/en not_active Expired
- 1976-07-08 YU YU1670/76A patent/YU41812B/xx unknown
- 1976-07-08 ZA ZA764065A patent/ZA764065B/xx unknown
- 1976-07-09 CA CA256,650A patent/CA1064903A/en not_active Expired
- 1976-07-09 HU HU76MA2797A patent/HU174603B/hu not_active IP Right Cessation
- 1976-07-09 CS CS764567A patent/CS208184B2/cs unknown
- 1976-07-10 RO RO7686932A patent/RO70354A/ro unknown
- 1976-07-10 ES ES449748A patent/ES449748A1/es not_active Expired
- 1976-07-10 PL PL1976191114A patent/PL99028B1/pl unknown
- 1976-07-12 PH PH18678A patent/PH13989A/en unknown
- 1976-07-12 FR FR7621313A patent/FR2316961A1/fr active Granted
- 1976-07-12 BE BE168849A patent/BE844053A/xx not_active IP Right Cessation
- 1976-07-12 JP JP51082846A patent/JPS5234915A/ja active Granted
-
1981
- 1981-07-16 HK HK336/81A patent/HK33681A/xx unknown
-
1986
- 1986-12-22 JP JP61304058A patent/JPS6366127A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| PH13989A (en) | 1980-11-28 |
| GB1550845A (en) | 1979-08-22 |
| PL99028B1 (pl) | 1978-06-30 |
| AU1572976A (en) | 1978-01-12 |
| SU786857A3 (ru) | 1980-12-07 |
| PT65302B (de) | 1977-12-13 |
| HU174603B (hu) | 1980-02-28 |
| PT65302A (de) | 1976-07-01 |
| DE2530953C3 (de) | 1994-07-07 |
| JPH0336808B2 (cs) | 1991-06-03 |
| FR2316961B1 (cs) | 1984-04-20 |
| DE2530953C2 (de) | 1994-07-07 |
| JPS5234915A (en) | 1977-03-17 |
| YU41812B (en) | 1988-02-29 |
| FI62099B (fi) | 1982-07-30 |
| AU510463B2 (en) | 1980-06-26 |
| HK33681A (en) | 1981-07-24 |
| CS208184B2 (en) | 1981-08-31 |
| BE844053A (fr) | 1977-01-12 |
| DE2530953A1 (de) | 1977-01-27 |
| JPS6221765B2 (cs) | 1987-05-14 |
| BG27379A3 (bg) | 1979-10-12 |
| ZA764065B (en) | 1977-07-27 |
| CA1064903A (en) | 1979-10-23 |
| RO70354A (ro) | 1982-03-24 |
| FI62099C (fi) | 1982-11-10 |
| FR2316961A1 (fr) | 1977-02-04 |
| JPS6366127A (ja) | 1988-03-24 |
| YU167076A (en) | 1983-06-30 |
| FI761895A7 (cs) | 1977-01-12 |
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