ES445874A1 - Procedimiento para la obtencion de 1-(indolil-3-alquil)-3- o-4-(ureido o guadino)-piperidinas. - Google Patents
Procedimiento para la obtencion de 1-(indolil-3-alquil)-3- o-4-(ureido o guadino)-piperidinas.Info
- Publication number
- ES445874A1 ES445874A1 ES445874A ES445874A ES445874A1 ES 445874 A1 ES445874 A1 ES 445874A1 ES 445874 A ES445874 A ES 445874A ES 445874 A ES445874 A ES 445874A ES 445874 A1 ES445874 A1 ES 445874A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- indolylalkylpiperidines
- guanidino
- piperidines
- etherified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55660075A | 1975-03-10 | 1975-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES445874A1 true ES445874A1 (es) | 1977-06-01 |
Family
ID=24222029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES445874A Expired ES445874A1 (es) | 1975-03-10 | 1976-03-08 | Procedimiento para la obtencion de 1-(indolil-3-alquil)-3- o-4-(ureido o guadino)-piperidinas. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4073911A (es) |
| JP (1) | JPS51113878A (es) |
| AU (1) | AU1175076A (es) |
| BE (1) | BE839347A (es) |
| DD (1) | DD124386A5 (es) |
| DE (1) | DE2609289A1 (es) |
| DK (1) | DK138893B (es) |
| ES (1) | ES445874A1 (es) |
| FI (1) | FI760584A (es) |
| FR (1) | FR2303541A1 (es) |
| GB (1) | GB1534351A (es) |
| GR (1) | GR60030B (es) |
| IL (1) | IL49171A (es) |
| NL (1) | NL7602508A (es) |
| NO (1) | NO760774L (es) |
| NZ (1) | NZ180255A (es) |
| PT (1) | PT64878B (es) |
| SE (1) | SE7602729L (es) |
| ZA (2) | ZA76475B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4350634A (en) | 1977-07-12 | 1982-09-21 | Sandoz Ltd. | N-Benzoyl-N'-3-indolyl-N'alkyl-1,3-diaminopropanes |
| GB1586817A (en) * | 1977-12-01 | 1981-03-25 | Wyeth John & Brother Ltd | Indole derivatives |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| NZ216720A (en) * | 1985-07-08 | 1990-09-26 | Bristol Myers Co | Diazinylpiperidine derivatives and pharmaceutical compositions |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| PT640081E (pt) * | 1992-03-31 | 2000-05-31 | Glaxo Group Ltd | Derivados de fenil-carbamatos e fenil-ureias substituidos sua preparacao e sua utilizacao como antagonistas 5-ht4 |
| JP3916092B2 (ja) * | 1993-09-17 | 2007-05-16 | 杏林製薬株式会社 | イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬 |
| US6489300B1 (en) * | 1997-07-31 | 2002-12-03 | Eugene D. Thorsett | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| FR2803298A1 (fr) * | 1999-12-30 | 2001-07-06 | Adir | Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP4520851B2 (ja) * | 2002-07-19 | 2010-08-11 | 明治乳業株式会社 | インドール誘導体及びこれを含有する医薬 |
| WO2004091514A2 (en) * | 2003-04-15 | 2004-10-28 | Merck & Co., Inc. | Cgrp receptor antagonists |
| CA2529196A1 (en) * | 2003-06-26 | 2005-02-17 | Merck & Co., Inc. | Benzodiazepine cgrp receptor antagonists |
| AU2005208834B2 (en) * | 2004-01-29 | 2009-10-08 | Merck Sharp & Dohme Corp. | CGRP receptor antagonists |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238215A (en) * | 1963-10-17 | 1966-03-01 | Sterling Drug Inc | 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines |
| GB1273563A (en) * | 1968-07-24 | 1972-05-10 | Wyeth John & Brother Ltd | Indoles |
-
1976
- 1976-01-28 ZA ZA760475A patent/ZA76475B/xx unknown
- 1976-02-02 US US05/654,254 patent/US4073911A/en not_active Expired - Lifetime
- 1976-02-27 SE SE7602729A patent/SE7602729L/xx unknown
- 1976-03-05 GB GB8902/76A patent/GB1534351A/en not_active Expired
- 1976-03-05 NO NO760774A patent/NO760774L/no unknown
- 1976-03-06 GR GR50261A patent/GR60030B/el unknown
- 1976-03-06 DE DE19762609289 patent/DE2609289A1/de active Pending
- 1976-03-08 FI FI760584A patent/FI760584A/fi not_active Application Discontinuation
- 1976-03-08 AU AU11750/76A patent/AU1175076A/en not_active Expired
- 1976-03-08 FR FR7606495A patent/FR2303541A1/fr active Granted
- 1976-03-08 IL IL49171A patent/IL49171A/xx unknown
- 1976-03-08 ES ES445874A patent/ES445874A1/es not_active Expired
- 1976-03-09 BE BE164977A patent/BE839347A/xx unknown
- 1976-03-09 NZ NZ180255A patent/NZ180255A/xx unknown
- 1976-03-09 ZA ZA761467A patent/ZA761467B/xx unknown
- 1976-03-09 PT PT64878A patent/PT64878B/pt unknown
- 1976-03-09 DK DK101476AA patent/DK138893B/da unknown
- 1976-03-09 DD DD191763A patent/DD124386A5/xx unknown
- 1976-03-10 JP JP51026622A patent/JPS51113878A/ja active Pending
- 1976-03-10 NL NL7602508A patent/NL7602508A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA761467B (en) | 1977-10-26 |
| IL49171A0 (en) | 1976-05-31 |
| DK101476A (es) | 1976-09-11 |
| PT64878B (en) | 1977-07-22 |
| DE2609289A1 (de) | 1976-09-30 |
| ZA76475B (en) | 1977-08-31 |
| GR60030B (en) | 1978-03-31 |
| FR2303541A1 (fr) | 1976-10-08 |
| FI760584A (es) | 1976-09-11 |
| NO760774L (es) | 1976-09-13 |
| NL7602508A (nl) | 1976-09-14 |
| FR2303541B1 (es) | 1979-10-05 |
| DK138893C (es) | 1979-04-23 |
| IL49171A (en) | 1978-12-17 |
| NZ180255A (en) | 1978-07-10 |
| US4073911A (en) | 1978-02-14 |
| PT64878A (en) | 1976-04-01 |
| SE7602729L (sv) | 1976-09-13 |
| DK138893B (da) | 1978-11-13 |
| AU1175076A (en) | 1977-09-15 |
| JPS51113878A (en) | 1976-10-07 |
| DD124386A5 (es) | 1977-02-16 |
| BE839347A (fr) | 1976-09-09 |
| GB1534351A (en) | 1978-12-06 |
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