ZA761467B - New indolylalkylpiperidines process for their manufacture and pharmaceutical preparations containing them - Google Patents

New indolylalkylpiperidines process for their manufacture and pharmaceutical preparations containing them

Info

Publication number
ZA761467B
ZA761467B ZA761467A ZA761467A ZA761467B ZA 761467 B ZA761467 B ZA 761467B ZA 761467 A ZA761467 A ZA 761467A ZA 761467 A ZA761467 A ZA 761467A ZA 761467 B ZA761467 B ZA 761467B
Authority
ZA
South Africa
Prior art keywords
indolylalkylpiperidines
manufacture
new
pharmaceutical preparations
preparations containing
Prior art date
Application number
ZA761467A
Other languages
English (en)
Inventor
C Huebner
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA761467B publication Critical patent/ZA761467B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
ZA761467A 1975-03-10 1976-03-09 New indolylalkylpiperidines process for their manufacture and pharmaceutical preparations containing them ZA761467B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55660075A 1975-03-10 1975-03-10

Publications (1)

Publication Number Publication Date
ZA761467B true ZA761467B (en) 1977-10-26

Family

ID=24222029

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA760475A ZA76475B (en) 1975-03-10 1976-01-28 Indolyalkylpiperidines
ZA761467A ZA761467B (en) 1975-03-10 1976-03-09 New indolylalkylpiperidines process for their manufacture and pharmaceutical preparations containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA760475A ZA76475B (en) 1975-03-10 1976-01-28 Indolyalkylpiperidines

Country Status (19)

Country Link
US (1) US4073911A (xx)
JP (1) JPS51113878A (xx)
AU (1) AU1175076A (xx)
BE (1) BE839347A (xx)
DD (1) DD124386A5 (xx)
DE (1) DE2609289A1 (xx)
DK (1) DK138893B (xx)
ES (1) ES445874A1 (xx)
FI (1) FI760584A (xx)
FR (1) FR2303541A1 (xx)
GB (1) GB1534351A (xx)
GR (1) GR60030B (xx)
IL (1) IL49171A (xx)
NL (1) NL7602508A (xx)
NO (1) NO760774L (xx)
NZ (1) NZ180255A (xx)
PT (1) PT64878B (xx)
SE (1) SE7602729L (xx)
ZA (2) ZA76475B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350634A (en) 1977-07-12 1982-09-21 Sandoz Ltd. N-Benzoyl-N'-3-indolyl-N'alkyl-1,3-diaminopropanes
GB1586817A (en) * 1977-12-01 1981-03-25 Wyeth John & Brother Ltd Indole derivatives
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
NZ216720A (en) * 1985-07-08 1990-09-26 Bristol Myers Co Diazinylpiperidine derivatives and pharmaceutical compositions
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
PT640081E (pt) * 1992-03-31 2000-05-31 Glaxo Group Ltd Derivados de fenil-carbamatos e fenil-ureias substituidos sua preparacao e sua utilizacao como antagonistas 5-ht4
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
US6489300B1 (en) * 1997-07-31 2002-12-03 Eugene D. Thorsett Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4520851B2 (ja) * 2002-07-19 2010-08-11 明治乳業株式会社 インドール誘導体及びこれを含有する医薬
WO2004091514A2 (en) * 2003-04-15 2004-10-28 Merck & Co., Inc. Cgrp receptor antagonists
CA2529196A1 (en) * 2003-06-26 2005-02-17 Merck & Co., Inc. Benzodiazepine cgrp receptor antagonists
AU2005208834B2 (en) * 2004-01-29 2009-10-08 Merck Sharp & Dohme Corp. CGRP receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
GB1273563A (en) * 1968-07-24 1972-05-10 Wyeth John & Brother Ltd Indoles

Also Published As

Publication number Publication date
IL49171A0 (en) 1976-05-31
DK101476A (xx) 1976-09-11
PT64878B (en) 1977-07-22
DE2609289A1 (de) 1976-09-30
ZA76475B (en) 1977-08-31
GR60030B (en) 1978-03-31
FR2303541A1 (fr) 1976-10-08
FI760584A (xx) 1976-09-11
NO760774L (xx) 1976-09-13
NL7602508A (nl) 1976-09-14
FR2303541B1 (xx) 1979-10-05
DK138893C (xx) 1979-04-23
ES445874A1 (es) 1977-06-01
IL49171A (en) 1978-12-17
NZ180255A (en) 1978-07-10
US4073911A (en) 1978-02-14
PT64878A (en) 1976-04-01
SE7602729L (sv) 1976-09-13
DK138893B (da) 1978-11-13
AU1175076A (en) 1977-09-15
JPS51113878A (en) 1976-10-07
DD124386A5 (xx) 1977-02-16
BE839347A (fr) 1976-09-09
GB1534351A (en) 1978-12-06

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