ES435110A1 - Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico. - Google Patents

Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico.

Info

Publication number
ES435110A1
ES435110A1 ES435110A ES435110A ES435110A1 ES 435110 A1 ES435110 A1 ES 435110A1 ES 435110 A ES435110 A ES 435110A ES 435110 A ES435110 A ES 435110A ES 435110 A1 ES435110 A1 ES 435110A1
Authority
ES
Spain
Prior art keywords
group
formula
transformed
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435110A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES435110A1 publication Critical patent/ES435110A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02Sulfinic acids; Derivatives thereof
    • C07C313/04Sulfinic acids; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES435110A 1974-02-26 1975-02-26 Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico. Expired ES435110A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12

Publications (1)

Publication Number Publication Date
ES435110A1 true ES435110A1 (es) 1977-03-16

Family

ID=27173851

Family Applications (2)

Application Number Title Priority Date Filing Date
ES435110A Expired ES435110A1 (es) 1974-02-26 1975-02-26 Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico.
ES452915A Expired ES452915A1 (es) 1974-02-26 1976-11-02 Procedimiento para la obtencion de derivados de acido 2-(3- amino-2-oxo-4-tio-1-azetilinil)-3-hidroxi sustituido croto- nico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES452915A Expired ES452915A1 (es) 1974-02-26 1976-11-02 Procedimiento para la obtencion de derivados de acido 2-(3- amino-2-oxo-4-tio-1-azetilinil)-3-hidroxi sustituido croto- nico.

Country Status (21)

Country Link
JP (1) JPS625919B2 (US06368395-20020409-C00050.png)
AR (1) AR208538A1 (US06368395-20020409-C00050.png)
AT (2) AT337362B (US06368395-20020409-C00050.png)
AU (1) AU498131B2 (US06368395-20020409-C00050.png)
BE (1) BE825919A (US06368395-20020409-C00050.png)
BG (1) BG26201A3 (US06368395-20020409-C00050.png)
CA (2) CA1059988A (US06368395-20020409-C00050.png)
DD (1) DD117074A5 (US06368395-20020409-C00050.png)
DE (1) DE2506330A1 (US06368395-20020409-C00050.png)
DK (2) DK73475A (US06368395-20020409-C00050.png)
ES (2) ES435110A1 (US06368395-20020409-C00050.png)
FI (1) FI66389C (US06368395-20020409-C00050.png)
FR (1) FR2261761B1 (US06368395-20020409-C00050.png)
GB (1) GB1503581A (US06368395-20020409-C00050.png)
HU (1) HU175212B (US06368395-20020409-C00050.png)
IE (1) IE40695B1 (US06368395-20020409-C00050.png)
IL (1) IL46699A (US06368395-20020409-C00050.png)
NL (1) NL7502292A (US06368395-20020409-C00050.png)
NO (1) NO750625L (US06368395-20020409-C00050.png)
NZ (1) NZ176623A (US06368395-20020409-C00050.png)
SE (3) SE431652B (US06368395-20020409-C00050.png)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
JPS5198265A (US06368395-20020409-C00050.png) * 1975-02-17 1976-08-30
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井 康博 薬液収納兼即効注出器
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 3−ヒドロキシセフェム誘導体の製造法
AU2003269416A1 (en) * 2002-11-01 2004-05-25 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of chloro methyl cephem derivatives
AU2012357986B2 (en) 2011-12-20 2017-02-02 Riboscience Llc 4'-Azido, 3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
AU2012357940B2 (en) 2011-12-20 2017-02-16 Riboscience Llc 2',4'-difluoro-2'-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication
MA46490A1 (fr) 2013-05-16 2021-04-30 Riboscience Llc Dérivés de nucléosides 4'- fluoro-2' - méthyle substitués
EA201592185A1 (ru) 2013-05-16 2016-05-31 Рибосайенс Ллк 4'-азидо, 3'-дезокси-3'-фторзамещенные нуклеозидные производные
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
AR112702A1 (es) 2017-09-21 2019-11-27 Riboscience Llc Derivados de nucleósidos sustituidos con 4’-fluoro-2’-metilo como inhibidores de la replicación de hcv arn

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Also Published As

Publication number Publication date
CA1080713A (en) 1980-07-01
AT337362B (de) 1977-06-27
FR2261761B1 (US06368395-20020409-C00050.png) 1978-08-18
DE2506330A1 (de) 1975-09-04
FI66389C (fi) 1984-10-10
BE825919A (fr) 1975-08-25
IL46699A (en) 1977-11-30
IL46699A0 (en) 1975-04-25
SE7807810L (sv) 1978-07-13
GB1503581A (en) 1978-03-15
IE40695B1 (en) 1979-08-01
FI750503A (US06368395-20020409-C00050.png) 1975-08-27
AU7849875A (en) 1976-08-26
CA1059988A (en) 1979-08-07
ATA28178A (de) 1978-10-15
DK348678A (da) 1978-08-07
DD117074A5 (US06368395-20020409-C00050.png) 1975-12-20
FR2261761A1 (US06368395-20020409-C00050.png) 1975-09-19
FI66389B (fi) 1984-06-29
AR208538A1 (es) 1977-02-15
AU498131B2 (en) 1979-02-15
HU175212B (hu) 1980-06-28
IE40695L (en) 1975-08-26
JPS625919B2 (US06368395-20020409-C00050.png) 1987-02-07
SE7501317L (US06368395-20020409-C00050.png) 1975-08-27
ES452915A1 (es) 1977-11-01
SE438854B (sv) 1985-05-13
NO750625L (US06368395-20020409-C00050.png) 1975-08-27
AT350068B (de) 1979-05-10
DK73475A (US06368395-20020409-C00050.png) 1975-10-20
SE438855B (sv) 1985-05-13
BG26201A3 (bg) 1979-02-15
ATA108275A (de) 1976-10-15
JPS50129590A (US06368395-20020409-C00050.png) 1975-10-13
SE431652B (sv) 1984-02-20
NZ176623A (en) 1978-04-03
SE7807811L (sv) 1978-07-13
NL7502292A (nl) 1975-08-28

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