ES423977A1 - Procedure for the preparation of new bencelomines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new bencelomines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES423977A1
ES423977A1 ES423977A ES423977A ES423977A1 ES 423977 A1 ES423977 A1 ES 423977A1 ES 423977 A ES423977 A ES 423977A ES 423977 A ES423977 A ES 423977A ES 423977 A1 ES423977 A1 ES 423977A1
Authority
ES
Spain
Prior art keywords
carbon atoms
radical
signifies
formula
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423977A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732337932 external-priority patent/DE2337932A1/en
Priority claimed from DE2346743A external-priority patent/DE2346743C3/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES423977A1 publication Critical patent/ES423977A1/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where it means a hydrogen atom, a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n means the numbers 0, 1 or 2 and the two radicals A and B mean hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means the numbers 1 or 2, R4 means a straight chain or branched alcohol radical with 1 to 4 carbon atoms, an alkenyl radical with 2 to 4 carbon atoms, a cycloalkyl radical with 3 or 4 carbon atoms or also a hydrogen atom, if R3 does not represent any hydrogen atom or R2 represents a branched alcoholic radical with 3 to 5 carbon atoms, possibly substituted with 1 to 3 hydroxyl groups, and l means the numbers 1 or 2, as well as their physiologically compatible acid addition salts, with organic or inorganic acids, characterized in that a compound of the general formula II is reacted, **(See formula)** wherein R1, Hal and l are as initially defined and R8 signifies an organic acyl radical, with an amine of the general formula III, **(See formula)** wherein R2 and R4 are as initially defined; and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
ES423977A 1973-07-26 1974-03-06 Procedure for the preparation of new bencelomines. (Machine-translation by Google Translate, not legally binding) Expired ES423977A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19732337932 DE2337932A1 (en) 1972-10-23 1973-07-26 N-substd. hydroxy-benzylamines prepn - by e.g. reacting benzyl alcohol derivs. with amines
DE2346743A DE2346743C3 (en) 1972-10-23 1973-09-17 2- or 4-Hydroxy-3,5-dihalogenobenzylamines, their physiologically tolerable salts, processes for their preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
ES423977A1 true ES423977A1 (en) 1976-06-16

Family

ID=25765548

Family Applications (2)

Application Number Title Priority Date Filing Date
ES423977A Expired ES423977A1 (en) 1973-07-26 1974-03-06 Procedure for the preparation of new bencelomines. (Machine-translation by Google Translate, not legally binding)
ES423978A Expired ES423978A1 (en) 1973-07-26 1974-03-16 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES423978A Expired ES423978A1 (en) 1973-07-26 1974-03-16 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
AT (2) ATA88475A (en)
BG (1) BG22383A3 (en)
ES (2) ES423977A1 (en)
PL (2) PL91888B1 (en)
SU (2) SU514564A3 (en)

Also Published As

Publication number Publication date
PL91889B1 (en) 1977-03-31
ATA88575A (en) 1975-07-15
SU514564A3 (en) 1976-05-15
ES423978A1 (en) 1976-07-01
ATA88475A (en) 1975-07-15
PL91888B1 (en) 1977-03-31
SU517249A3 (en) 1976-06-05
BG22383A3 (en) 1977-02-20

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