ES408929A1 - Procedimiento para preparar derivados de decahidroquinoli- noles sustituidos. - Google Patents
Procedimiento para preparar derivados de decahidroquinoli- noles sustituidos.Info
- Publication number
- ES408929A1 ES408929A1 ES408929A ES408929A ES408929A1 ES 408929 A1 ES408929 A1 ES 408929A1 ES 408929 A ES408929 A ES 408929A ES 408929 A ES408929 A ES 408929A ES 408929 A1 ES408929 A1 ES 408929A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- agents
- derivatives
- useful
- arrhythmia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 abstract 1
- 229930182837 (R)-adrenaline Natural products 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- -1 aralkyl radical Chemical class 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960005139 epinephrine Drugs 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 229960002748 norepinephrine Drugs 0.000 abstract 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
- 206010047302 ventricular tachycardia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5446671A GB1364723A (en) | 1971-11-23 | 1971-11-23 | Decahydroquinolinol derivatives and process for preparing the sa me |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES408929A1 true ES408929A1 (es) | 1975-10-16 |
Family
ID=10471095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408929A Expired ES408929A1 (es) | 1971-11-23 | 1972-11-23 | Procedimiento para preparar derivados de decahidroquinoli- noles sustituidos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3882129A (en, 2012) |
| BE (1) | BE791678A (en, 2012) |
| CH (1) | CH562801A5 (en, 2012) |
| DE (1) | DE2257397C3 (en, 2012) |
| ES (1) | ES408929A1 (en, 2012) |
| FR (1) | FR2160939B1 (en, 2012) |
| GB (1) | GB1364723A (en, 2012) |
| NL (1) | NL176171C (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4173636A (en) * | 1975-12-16 | 1979-11-06 | Labaz | Decahydroquinolines, pharmaceutical compositions and methods of use |
| FR2465724A1 (fr) * | 1979-09-19 | 1981-03-27 | Sanofi Sa | Nouveaux derives de decahydroquinoleinol, leur procede de preparation ainsi que leurs applications en therapeutique |
| FR2565979B1 (fr) * | 1984-06-13 | 1987-03-20 | Labaz Sanofi Nv | Nouveaux derives de decahydroquinoleinol, leur procede de preparation et les compositions les contenant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3056792A (en) * | 1958-06-04 | 1962-10-02 | Geschickter Fund Med Res | Unsymmetrical 1, 3-diamino-2-propanols |
| BE610830A (en, 2012) * | 1960-12-01 | |||
| NL279583A (en, 2012) * | 1961-06-29 | |||
| US3171838A (en) * | 1961-10-10 | 1965-03-02 | Res Lab Dr C Janssen N V | Aroylalkyl and hydroxyaralkyl derivatives of 4-(n-arylalkanamido)-piperidines and related compounds |
-
0
- BE BE791678D patent/BE791678A/xx not_active IP Right Cessation
-
1971
- 1971-11-23 GB GB5446671A patent/GB1364723A/en not_active Expired
-
1972
- 1972-11-16 CH CH1669872A patent/CH562801A5/xx not_active IP Right Cessation
- 1972-11-22 NL NLAANVRAGE7215791,A patent/NL176171C/xx not_active IP Right Cessation
- 1972-11-22 FR FR7241413A patent/FR2160939B1/fr not_active Expired
- 1972-11-23 ES ES408929A patent/ES408929A1/es not_active Expired
- 1972-11-23 DE DE2257397A patent/DE2257397C3/de not_active Expired
- 1972-11-24 US US309446A patent/US3882129A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE2257397A1 (de) | 1973-05-30 |
| FR2160939B1 (en, 2012) | 1976-07-02 |
| CH562801A5 (en, 2012) | 1975-06-13 |
| US3882129A (en) | 1975-05-06 |
| DE2257397B2 (de) | 1980-06-26 |
| GB1364723A (en) | 1974-08-29 |
| NL176171C (nl) | 1985-03-01 |
| NL176171B (nl) | 1984-10-01 |
| NL7215791A (en, 2012) | 1973-05-25 |
| FR2160939A1 (en, 2012) | 1973-07-06 |
| DE2257397C3 (de) | 1981-04-16 |
| BE791678A (fr) | 1973-05-21 |
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