ATE72238T1 - Imidazoliumsalze, zwischenprodukte fuer ihre herstellung sowie ihre verwendung. - Google Patents
Imidazoliumsalze, zwischenprodukte fuer ihre herstellung sowie ihre verwendung.Info
- Publication number
- ATE72238T1 ATE72238T1 AT84108015T AT84108015T ATE72238T1 AT E72238 T1 ATE72238 T1 AT E72238T1 AT 84108015 T AT84108015 T AT 84108015T AT 84108015 T AT84108015 T AT 84108015T AT E72238 T1 ATE72238 T1 AT E72238T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazolium salts
- preparation
- intermediate products
- imidazolium
- refractoriness
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2635—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving a phosphorus compound, e.g. Wittig synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
- C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/483—Monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Gas Separation By Absorption (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/513,143 US4581370A (en) | 1983-07-12 | 1983-07-12 | Antiarrhythmic imidazoliums |
| EP84108015A EP0131302B1 (de) | 1983-07-12 | 1984-07-09 | Imidazoliumsalze, Zwischenprodukte für ihre Herstellung sowie ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE72238T1 true ATE72238T1 (de) | 1992-02-15 |
Family
ID=24042059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84108015T ATE72238T1 (de) | 1983-07-12 | 1984-07-09 | Imidazoliumsalze, zwischenprodukte fuer ihre herstellung sowie ihre verwendung. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4581370A (de) |
| EP (1) | EP0131302B1 (de) |
| JP (1) | JPH08815B2 (de) |
| AT (1) | ATE72238T1 (de) |
| AU (1) | AU582538B2 (de) |
| CA (1) | CA1289563C (de) |
| DE (1) | DE3485488D1 (de) |
| DK (1) | DK339184A (de) |
| FI (1) | FI90232C (de) |
| GR (1) | GR82282B (de) |
| IE (1) | IE59337B1 (de) |
| IL (1) | IL72354A (de) |
| NO (1) | NO168300C (de) |
| NZ (1) | NZ208831A (de) |
| ZA (1) | ZA845410B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0149976A3 (de) * | 1983-12-30 | 1986-12-10 | Ciba-Geigy Ag | Substituierte Imidazole |
| US4609670A (en) * | 1984-11-13 | 1986-09-02 | Eli Lilly And Company | Imidazolium hypoglycemic agents |
| DE3674054D1 (de) * | 1985-04-26 | 1990-10-18 | Hoffmann La Roche | 1,3-disubstituierte imidazoliumsalze. |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
| GB8707120D0 (en) * | 1987-03-25 | 1987-04-29 | Pfizer Ltd | Antiarrhythmic agents |
| DE3876006T2 (de) * | 1987-04-14 | 1993-03-25 | Glaxo Group Ltd | Keton-derivate. |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| HU221317B1 (en) * | 1991-08-14 | 2002-09-28 | Procter & Gamble Pharma | 2,4-imidazolidinedione derivatives and antiarrhythmic and antifibrillatory compositions containing them, and process for producing them |
| RU2142461C1 (ru) * | 1991-08-14 | 1999-12-10 | Проктер энд Гэмбл Фармасьютикалз, Инк. | Циклические соединения мочевины, фармацевтическая композиция и способ лечения |
| BR9206353A (pt) * | 1991-08-14 | 1995-11-07 | Procter & Gamble Pharma | Uretanos cíclicos utilizáveis como agentes antiarrítmicos e antifibrilatórios |
| US5635521A (en) * | 1991-09-23 | 1997-06-03 | Sandoz Ltd. | Imidazolylmethyl-pyridines |
| WO1993012108A1 (en) * | 1991-12-18 | 1993-06-24 | Schering Corporation | Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring |
| GB9127304D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| US5183813A (en) * | 1992-02-19 | 1993-02-02 | Sterling Winthrop Inc. | Antiarrhythmic agents |
| US6031109A (en) * | 1993-06-22 | 2000-02-29 | Knoll Aktiengesellschaft | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents |
| GB9312893D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| FR2766179B1 (fr) * | 1997-07-16 | 2000-03-17 | Oreal | Nouvelles bases d'oxydation cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2766178B1 (fr) * | 1997-07-16 | 2000-03-17 | Oreal | Nouvelles bases d'oxydation cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2782718B1 (fr) * | 1998-09-02 | 2000-11-10 | Oreal | Nouveaux composes cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2782719B1 (fr) * | 1998-09-02 | 2000-11-10 | Oreal | Nouvelles orthophenylenediamines cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| JP4620286B2 (ja) * | 2001-06-05 | 2011-01-26 | 富士フイルム株式会社 | 電解質組成物、光電変換素子及び光電気化学電池 |
| CN1659131A (zh) | 2002-04-08 | 2005-08-24 | 葛兰素集团有限公司 | 2－((2－烷氧基)－苯基)－环戊－1－烯基)芳香碳－以及杂环羧酸及其衍生物 |
| GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
| JP2008133248A (ja) * | 2006-10-24 | 2008-06-12 | Sanyo Chem Ind Ltd | イミダゾリウム塩の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2493318A (en) * | 1945-07-14 | 1950-01-03 | Lilly Co Eli | Imidazolium compounds |
| FR8357M (de) * | 1966-09-08 | 1971-02-08 | ||
| SE7600674L (sv) * | 1975-02-05 | 1976-08-06 | Rohm & Haas | Fungicider |
| DE2510525C3 (de) * | 1975-03-11 | 1978-03-30 | Th. Goldschmidt Ag, 4300 Essen | Quartäre 2-Alkylimidazoliumsalze |
| JPS5488268A (en) * | 1977-10-19 | 1979-07-13 | Wellcome Found | Novel imidazole derivatives*their manufacture and medical composition |
| JPS5479278A (en) * | 1977-12-05 | 1979-06-25 | Nippon Soda Co Ltd | Imidazolium halide |
| IT1097314B (it) * | 1978-07-26 | 1985-08-31 | Recordati Chem Pharm | Derivati dell'imidazolo ad attivita' anticonvulsivante |
| FR2486079A1 (fr) * | 1980-07-07 | 1982-01-08 | Rhone Poulenc Agrochimie | Sels quaternaires d'alcoyl-1-imidazolium de l'acide phosphoreux ou ses monoesters, procedes pour les preparer et compositions fongicides les contenant |
| JPS5838261A (ja) * | 1981-08-29 | 1983-03-05 | Kissei Pharmaceut Co Ltd | 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法 |
| JPS5855466A (ja) * | 1981-09-28 | 1983-04-01 | Kissei Pharmaceut Co Ltd | 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法 |
| DE3319845A1 (de) * | 1983-06-01 | 1984-12-06 | Basf Ag, 6700 Ludwigshafen | Arylalkylimidazolium- und -triazoliumsalze, verfahren zu ihrer herstellung und ihre verwendung als mikrozide |
-
1983
- 1983-07-12 US US06/513,143 patent/US4581370A/en not_active Expired - Fee Related
-
1984
- 1984-07-09 EP EP84108015A patent/EP0131302B1/de not_active Expired - Lifetime
- 1984-07-09 DE DE8484108015T patent/DE3485488D1/de not_active Expired - Lifetime
- 1984-07-09 AT AT84108015T patent/ATE72238T1/de not_active IP Right Cessation
- 1984-07-09 NZ NZ208831A patent/NZ208831A/xx unknown
- 1984-07-09 IL IL72354A patent/IL72354A/xx not_active IP Right Cessation
- 1984-07-10 DK DK339184A patent/DK339184A/da not_active Application Discontinuation
- 1984-07-10 FI FI842760A patent/FI90232C/fi not_active IP Right Cessation
- 1984-07-11 CA CA000458676A patent/CA1289563C/en not_active Expired - Lifetime
- 1984-07-11 GR GR75280A patent/GR82282B/el unknown
- 1984-07-11 NO NO842835A patent/NO168300C/no unknown
- 1984-07-11 IE IE177484A patent/IE59337B1/en not_active IP Right Cessation
- 1984-07-12 ZA ZA845410A patent/ZA845410B/xx unknown
- 1984-07-12 AU AU30543/84A patent/AU582538B2/en not_active Ceased
- 1984-07-12 JP JP59143414A patent/JPH08815B2/ja not_active Expired - Lifetime
-
1986
- 1986-07-03 US US06/881,760 patent/US4689341A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0131302A2 (de) | 1985-01-16 |
| NO168300B (no) | 1991-10-28 |
| AU3054384A (en) | 1985-01-17 |
| US4689341A (en) | 1987-08-25 |
| FI842760A0 (fi) | 1984-07-10 |
| IL72354A (en) | 1988-11-30 |
| IE59337B1 (en) | 1994-02-09 |
| ZA845410B (en) | 1985-02-27 |
| FI842760A (fi) | 1985-01-13 |
| CA1289563C (en) | 1991-09-24 |
| IL72354A0 (en) | 1984-11-30 |
| DK339184D0 (da) | 1984-07-10 |
| FI90232B (fi) | 1993-09-30 |
| IE841774L (en) | 1985-01-12 |
| AU582538B2 (en) | 1989-04-06 |
| GR82282B (de) | 1984-12-13 |
| JPS6038366A (ja) | 1985-02-27 |
| US4581370A (en) | 1986-04-08 |
| JPH08815B2 (ja) | 1996-01-10 |
| DE3485488D1 (de) | 1992-03-12 |
| DK339184A (da) | 1985-01-13 |
| EP0131302A3 (en) | 1987-06-16 |
| NO842835L (no) | 1985-01-14 |
| FI90232C (fi) | 1994-01-10 |
| NO168300C (no) | 1992-02-05 |
| NZ208831A (en) | 1988-09-29 |
| EP0131302B1 (de) | 1992-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE72238T1 (de) | Imidazoliumsalze, zwischenprodukte fuer ihre herstellung sowie ihre verwendung. | |
| DE3581699D1 (de) | Bis-dimethoxymethyl(trimethoxybenzyl)isochinolinium-salze, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| AU1331588A (en) | Method for treatment of alcohol abuse | |
| PT77898B (en) | Process for the preparation of substituted 4-amino-methylenochromanes and 4-aminomethylenecromenes acting on the blood circulation and application thereof in the preparation of pharmaceutical compositions acting on the blood circulation | |
| AU557590B2 (en) | Aroylimidazolones | |
| PL268927A1 (en) | Method of obtaining novel derivatives of benzimidazole | |
| FI854926A (fi) | Foerfarande foer framstaellning av farmakologiskt aktiva pyrrolobensimidazoler. | |
| ES2051885T3 (es) | 4-(1h-imidazol-1-il)-benzamidas sustituidas como agentes antiarritmicos. | |
| IT8547683A0 (it) | Procedimento per la preparazione dicomposti 1,3-diossolan-4-metanolici otticamente attivi | |
| NO166863C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituert-1,2-dihydro-3h-pyrrolo-(1,2-a)-pyrrol-1-carboxylsyrer ut fra deres tilsvarende nitriler. | |
| ES472847A1 (es) | Procedimiento para la preparacion de la 2-bromoergosina y sus sales acidas de adicion | |
| DE69501359D1 (de) | Verwendung von Phosphatdiestern zur Behandlung von Erkrankungen der Retina | |
| HUT42770A (en) | Process for preparing novel pyrrolo-benzimidazole derivatives, pyrrolo -benzoxazole derivatives and pyrrolo-benzthiazole derivatives and pharmaceutical compositions comprising the same | |
| CA2038025A1 (en) | Optically active alkylenedioxybenzene derivatives and their use in therapy | |
| ATE30582T1 (de) | Ungesaettigte arylalkylammoniumsalze. | |
| EP0207483A3 (en) | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | |
| ES547603A0 (es) | Un procedimiento para preparar derivados de piridina | |
| NO164599C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktivt 7-d-mandelamido-3-(1-sulfometyl-tetrazol-5-yl)-tiometyl-3-cefem-4-karboksylsyre-mononatriumsalt. | |
| AU7196987A (en) | 1,4-dihydropyridine derivatives, process for their preparation and medicaments containing these compounds | |
| NO903585L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-oksaziner. | |
| EP0118867A3 (de) | Substituierte 4,10-Dihydro-10-oxothienobenzodiazepine, Methode zu ihrer Herstellung, Zwischenprodukte und ihre Anwendung als Arzneimittel | |
| NO156866C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 17s, 17's-bisspartein og akseptable syreaddisjonssalter. | |
| ATE155479T1 (de) | Neue cytarabin-derivate, ihre herstellung und verwendung | |
| ATE56360T1 (de) | Zusammensetzung zur herstellung eines arzneimittels zur therapeutischen behandlung von hauttrauma. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee | ||
| EEFA | Change of the company name |