FI842760A0 - Menetelmä terapeuttisesti aktiivisten imidatsoliumyhdisteiden valmistamiseksi - Google Patents
Menetelmä terapeuttisesti aktiivisten imidatsoliumyhdisteiden valmistamiseksiInfo
- Publication number
- FI842760A0 FI842760A0 FI842760A FI842760A FI842760A0 FI 842760 A0 FI842760 A0 FI 842760A0 FI 842760 A FI842760 A FI 842760A FI 842760 A FI842760 A FI 842760A FI 842760 A0 FI842760 A0 FI 842760A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- therapeutically active
- imidazolium compounds
- active imidazolium
- imidazolium salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2635—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving a phosphorus compound, e.g. Wittig synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
- C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/483—Monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Gas Separation By Absorption (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/513,143 US4581370A (en) | 1983-07-12 | 1983-07-12 | Antiarrhythmic imidazoliums |
| US51314383 | 1983-07-12 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI842760A0 true FI842760A0 (fi) | 1984-07-10 |
| FI842760A FI842760A (fi) | 1985-01-13 |
| FI90232B FI90232B (fi) | 1993-09-30 |
| FI90232C FI90232C (fi) | 1994-01-10 |
Family
ID=24042059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI842760A FI90232C (fi) | 1983-07-12 | 1984-07-10 | Menetelmä terapeuttisesti aktiivisten imidatsoliumyhdisteiden valmistamiseksi |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4581370A (fi) |
| EP (1) | EP0131302B1 (fi) |
| JP (1) | JPH08815B2 (fi) |
| AT (1) | ATE72238T1 (fi) |
| AU (1) | AU582538B2 (fi) |
| CA (1) | CA1289563C (fi) |
| DE (1) | DE3485488D1 (fi) |
| DK (1) | DK339184A (fi) |
| FI (1) | FI90232C (fi) |
| GR (1) | GR82282B (fi) |
| IE (1) | IE59337B1 (fi) |
| IL (1) | IL72354A (fi) |
| NO (1) | NO168300C (fi) |
| NZ (1) | NZ208831A (fi) |
| ZA (1) | ZA845410B (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0149976A3 (de) * | 1983-12-30 | 1986-12-10 | Ciba-Geigy Ag | Substituierte Imidazole |
| US4609670A (en) * | 1984-11-13 | 1986-09-02 | Eli Lilly And Company | Imidazolium hypoglycemic agents |
| EP0200947B1 (de) * | 1985-04-26 | 1990-09-12 | F. Hoffmann-La Roche Ag | 1,3-Disubstituierte Imidazoliumsalze |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
| GB8707120D0 (en) * | 1987-03-25 | 1987-04-29 | Pfizer Ltd | Antiarrhythmic agents |
| EP0291172B1 (en) * | 1987-04-14 | 1992-11-19 | Glaxo Group Limited | Ketone derivatives |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| CA2115427C (en) * | 1991-08-14 | 2000-05-02 | Stanford Salvatore Pelosi Jr. | Novel 4-oxocyclic ureas useful as antiarrhythmic and antifibrillatory agents |
| ES2141725T3 (es) * | 1991-08-14 | 2000-04-01 | Procter & Gamble Pharma | Derivados de oxazolidinona, utiles como agentes antiarritmicos y antifibriladores. |
| EP0891976B1 (en) * | 1991-08-14 | 2002-10-16 | Procter & Gamble Pharmaceuticals | Novel cyclic ureas useful as antiarrhythmic and antifibrillatory agents |
| US5635521A (en) * | 1991-09-23 | 1997-06-03 | Sandoz Ltd. | Imidazolylmethyl-pyridines |
| JPH07121939B2 (ja) * | 1991-12-18 | 1995-12-25 | シェリング・コーポレーション | 窒素含有４または５員複素環で置換されたイミダゾリルまたはイミダゾイルアルキル化合物 |
| GB9127304D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| US5183813A (en) * | 1992-02-19 | 1993-02-02 | Sterling Winthrop Inc. | Antiarrhythmic agents |
| US6031109A (en) * | 1993-06-22 | 2000-02-29 | Knoll Aktiengesellschaft | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents |
| GB9312893D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| FR2766179B1 (fr) * | 1997-07-16 | 2000-03-17 | Oreal | Nouvelles bases d'oxydation cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2766178B1 (fr) * | 1997-07-16 | 2000-03-17 | Oreal | Nouvelles bases d'oxydation cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2782719B1 (fr) * | 1998-09-02 | 2000-11-10 | Oreal | Nouvelles orthophenylenediamines cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| FR2782718B1 (fr) * | 1998-09-02 | 2000-11-10 | Oreal | Nouveaux composes cationiques, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture |
| JP4620286B2 (ja) * | 2001-06-05 | 2011-01-26 | 富士フイルム株式会社 | 電解質組成物、光電変換素子及び光電気化学電池 |
| CN1659131A (zh) | 2002-04-08 | 2005-08-24 | 葛兰素集团有限公司 | 2－((2－烷氧基)－苯基)－环戊－1－烯基)芳香碳－以及杂环羧酸及其衍生物 |
| GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
| JP2008133248A (ja) * | 2006-10-24 | 2008-06-12 | Sanyo Chem Ind Ltd | イミダゾリウム塩の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2493318A (en) * | 1945-07-14 | 1950-01-03 | Lilly Co Eli | Imidazolium compounds |
| FR8357M (fi) * | 1966-09-08 | 1971-02-08 | ||
| SE7600674L (sv) * | 1975-02-05 | 1976-08-06 | Rohm & Haas | Fungicider |
| DE2510525C3 (de) * | 1975-03-11 | 1978-03-30 | Th. Goldschmidt Ag, 4300 Essen | Quartäre 2-Alkylimidazoliumsalze |
| AT370095B (de) * | 1977-10-19 | 1983-02-25 | Wellcome Found | Verfahren zum herstellen von neuen 1-aryl-alkyl-imidazolderivaten und deren salzen |
| JPS5479278A (en) * | 1977-12-05 | 1979-06-25 | Nippon Soda Co Ltd | Imidazolium halide |
| IT1097314B (it) * | 1978-07-26 | 1985-08-31 | Recordati Chem Pharm | Derivati dell'imidazolo ad attivita' anticonvulsivante |
| FR2486079A1 (fr) * | 1980-07-07 | 1982-01-08 | Rhone Poulenc Agrochimie | Sels quaternaires d'alcoyl-1-imidazolium de l'acide phosphoreux ou ses monoesters, procedes pour les preparer et compositions fongicides les contenant |
| JPS5838261A (ja) * | 1981-08-29 | 1983-03-05 | Kissei Pharmaceut Co Ltd | 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法 |
| JPS5855466A (ja) * | 1981-09-28 | 1983-04-01 | Kissei Pharmaceut Co Ltd | 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法 |
| DE3319845A1 (de) * | 1983-06-01 | 1984-12-06 | Basf Ag, 6700 Ludwigshafen | Arylalkylimidazolium- und -triazoliumsalze, verfahren zu ihrer herstellung und ihre verwendung als mikrozide |
-
1983
- 1983-07-12 US US06/513,143 patent/US4581370A/en not_active Expired - Fee Related
-
1984
- 1984-07-09 NZ NZ208831A patent/NZ208831A/xx unknown
- 1984-07-09 DE DE8484108015T patent/DE3485488D1/de not_active Expired - Lifetime
- 1984-07-09 AT AT84108015T patent/ATE72238T1/de not_active IP Right Cessation
- 1984-07-09 EP EP84108015A patent/EP0131302B1/en not_active Expired - Lifetime
- 1984-07-09 IL IL72354A patent/IL72354A/xx not_active IP Right Cessation
- 1984-07-10 FI FI842760A patent/FI90232C/fi not_active IP Right Cessation
- 1984-07-10 DK DK339184A patent/DK339184A/da not_active Application Discontinuation
- 1984-07-11 CA CA000458676A patent/CA1289563C/en not_active Expired - Lifetime
- 1984-07-11 IE IE177484A patent/IE59337B1/en not_active IP Right Cessation
- 1984-07-11 NO NO842835A patent/NO168300C/no unknown
- 1984-07-11 GR GR75280A patent/GR82282B/el unknown
- 1984-07-12 ZA ZA845410A patent/ZA845410B/xx unknown
- 1984-07-12 JP JP59143414A patent/JPH08815B2/ja not_active Expired - Lifetime
- 1984-07-12 AU AU30543/84A patent/AU582538B2/en not_active Ceased
-
1986
- 1986-07-03 US US06/881,760 patent/US4689341A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0131302A2 (en) | 1985-01-16 |
| JPS6038366A (ja) | 1985-02-27 |
| US4581370A (en) | 1986-04-08 |
| DE3485488D1 (de) | 1992-03-12 |
| DK339184D0 (da) | 1984-07-10 |
| JPH08815B2 (ja) | 1996-01-10 |
| FI90232B (fi) | 1993-09-30 |
| ZA845410B (en) | 1985-02-27 |
| CA1289563C (en) | 1991-09-24 |
| NO842835L (no) | 1985-01-14 |
| DK339184A (da) | 1985-01-13 |
| EP0131302B1 (en) | 1992-01-29 |
| AU582538B2 (en) | 1989-04-06 |
| NZ208831A (en) | 1988-09-29 |
| IE841774L (en) | 1985-01-12 |
| IL72354A0 (en) | 1984-11-30 |
| NO168300B (no) | 1991-10-28 |
| ATE72238T1 (de) | 1992-02-15 |
| NO168300C (no) | 1992-02-05 |
| AU3054384A (en) | 1985-01-17 |
| FI842760A (fi) | 1985-01-13 |
| GR82282B (fi) | 1984-12-13 |
| EP0131302A3 (en) | 1987-06-16 |
| FI90232C (fi) | 1994-01-10 |
| US4689341A (en) | 1987-08-25 |
| IL72354A (en) | 1988-11-30 |
| IE59337B1 (en) | 1994-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Owner name: SCHERING AKTIENGESELLSCHAFT |
|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: SCHERING AKTIENGESELLSCHAFT |