ES408929A1 - 4-Carbamoyl-1-(p-fluorobenzoylpropyl)decahydroquinaline derivatives - Google Patents

4-Carbamoyl-1-(p-fluorobenzoylpropyl)decahydroquinaline derivatives

Info

Publication number
ES408929A1
ES408929A1 ES408929A ES408929A ES408929A1 ES 408929 A1 ES408929 A1 ES 408929A1 ES 408929 A ES408929 A ES 408929A ES 408929 A ES408929 A ES 408929A ES 408929 A1 ES408929 A1 ES 408929A1
Authority
ES
Spain
Prior art keywords
radical
agents
derivatives
useful
arrhythmia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES408929A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of ES408929A1 publication Critical patent/ES408929A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Decahydroquinolinol derivatives of the general formula AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, WHEREIN R represents hydrogen, methyl, ethyl, n-propyl, isopropyl, allyl, a cycloaliphatic radical, for example cyclopentyl or cyclohexyl, a phenyl radical optionally substituted by a fluorine, chlorine, or bromine atom or methoxy group, or an aralkyl radical, for example a benzyl radical, and X represents an oxygen or sulphur atom, are useful anti-adrenergic agents which exert a powerful action against the toxicity of biogenetic amines such as epinephrine and norepinephrine, as anti-arrhythmia agents useful in the treatment of cardiac arrhythmia such as ventricular tachycardia, as sedatives, and as agents for the relief of certain forms of hypertension and diseases of the peripheral vascular system.
ES408929A 1971-11-23 1972-11-23 4-Carbamoyl-1-(p-fluorobenzoylpropyl)decahydroquinaline derivatives Expired ES408929A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5446671A GB1364723A (en) 1971-11-23 1971-11-23 Decahydroquinolinol derivatives and process for preparing the sa me

Publications (1)

Publication Number Publication Date
ES408929A1 true ES408929A1 (en) 1975-10-16

Family

ID=10471095

Family Applications (1)

Application Number Title Priority Date Filing Date
ES408929A Expired ES408929A1 (en) 1971-11-23 1972-11-23 4-Carbamoyl-1-(p-fluorobenzoylpropyl)decahydroquinaline derivatives

Country Status (8)

Country Link
US (1) US3882129A (en)
BE (1) BE791678A (en)
CH (1) CH562801A5 (en)
DE (1) DE2257397C3 (en)
ES (1) ES408929A1 (en)
FR (1) FR2160939B1 (en)
GB (1) GB1364723A (en)
NL (1) NL176171C (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173636A (en) * 1975-12-16 1979-11-06 Labaz Decahydroquinolines, pharmaceutical compositions and methods of use
FR2465724A1 (en) * 1979-09-19 1981-03-27 Sanofi Sa NOVEL DECAHYDROQUINOLEINOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF
FR2565979B1 (en) * 1984-06-13 1987-03-20 Labaz Sanofi Nv NOVEL DECAHYDROQUINOLEINOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3056792A (en) * 1958-06-04 1962-10-02 Geschickter Fund Med Res Unsymmetrical 1, 3-diamino-2-propanols
BE610830A (en) * 1960-12-01
NL279583A (en) * 1961-06-29
US3171838A (en) * 1961-10-10 1965-03-02 Res Lab Dr C Janssen N V Aroylalkyl and hydroxyaralkyl derivatives of 4-(n-arylalkanamido)-piperidines and related compounds

Also Published As

Publication number Publication date
CH562801A5 (en) 1975-06-13
US3882129A (en) 1975-05-06
BE791678A (en) 1973-05-21
GB1364723A (en) 1974-08-29
FR2160939B1 (en) 1976-07-02
NL176171B (en) 1984-10-01
DE2257397B2 (en) 1980-06-26
NL176171C (en) 1985-03-01
FR2160939A1 (en) 1973-07-06
NL7215791A (en) 1973-05-25
DE2257397A1 (en) 1973-05-30
DE2257397C3 (en) 1981-04-16

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