ES368538A1 - Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES368538A1
ES368538A1 ES368538A ES368538A ES368538A1 ES 368538 A1 ES368538 A1 ES 368538A1 ES 368538 A ES368538 A ES 368538A ES 368538 A ES368538 A ES 368538A ES 368538 A1 ES368538 A1 ES 368538A1
Authority
ES
Spain
Prior art keywords
acid
isocyanate
paminoalquil
bencensulfonamida
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES368538A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES368538A1 publication Critical patent/ES368538A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Novel compounds I (including salts with bases and hydrates thereof) wherein m is 2 or 3, R 1 is H or Me and R 2 is H, C 1 to C 6 alkyl or phenyl optionally mono- or disubstituted by halogen, C 1 to C 4 alkyl or C 1 to C 4 alkoxy, or is trifluoromethylphenyl, are obtained by standard methods for sulphonyl-ureas. Octahydro-1,2,4-methenopentalen-5-amine is ob tained by reacting the corresponding 5-isocyanate with glacial acetic acid and acetic anhydride or with an alkanol and hydrolysing the product so obtained the isocyanate is prepared by treating the corresponding 5-acid hydrazide (prepared by interaction of hydrazine hydrate and the corresponding 5-carboxylic acid-#-ethoxyethyl ester which, in turn is obtained by interaction of acrylic acid-#-ethoxyethyl ester stabilized with hydroquinone monomethyl ether, and 2,5- norbornadiene in the presence of nickel-tricarbonyl triphenylphosphine) with sodium nitrite in the presence of concentrated hydrochloric acid. Pharmaceutical preparations showing hypoglycemic action contain I as active ingredient administration may be orally or parenterally.
ES368538A 1968-06-20 1969-06-19 Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding) Expired ES368538A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH921568A CH499501A (en) 1968-06-20 1968-06-20 Process for the preparation of new derivatives of p-aminoalkyl-benzenesulfonamide

Publications (1)

Publication Number Publication Date
ES368538A1 true ES368538A1 (en) 1971-05-01

Family

ID=4349591

Family Applications (2)

Application Number Title Priority Date Filing Date
ES368538A Expired ES368538A1 (en) 1968-06-20 1969-06-19 Procedure for the preparation of new derivatives of paminoalquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding)
ES368539A Expired ES368539A1 (en) 1968-06-20 1969-06-19 Procedure for the preparation of new derivatives of paminoalaquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES368539A Expired ES368539A1 (en) 1968-06-20 1969-06-19 Procedure for the preparation of new derivatives of paminoalaquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding)

Country Status (15)

Country Link
AT (1) AT291279B (en)
BE (1) BE734867A (en)
CA (1) CA954531A (en)
CH (2) CH499501A (en)
DE (1) DE1931197A1 (en)
DK (1) DK123472B (en)
ES (2) ES368538A1 (en)
FI (1) FI49960C (en)
FR (1) FR2011310A1 (en)
GB (1) GB1258594A (en)
IE (1) IE33375B1 (en)
IL (1) IL32432A (en)
NL (1) NL6909085A (en)
NO (1) NO125817B (en)
SE (1) SE359825B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1244174C2 (en) * 1965-09-10 1968-01-18 Hoechst Ag Process for the preparation of benzenesulfonylureas

Also Published As

Publication number Publication date
CA954531A (en) 1974-09-10
ES368539A1 (en) 1971-05-01
IL32432A (en) 1973-11-28
GB1258594A (en) 1971-12-30
FI49960C (en) 1975-11-10
BE734867A (en) 1969-12-19
NO125817B (en) 1972-11-06
CH499501A (en) 1970-11-30
CH499502A (en) 1970-11-30
IL32432A0 (en) 1969-08-27
FI49960B (en) 1975-07-31
DK123472B (en) 1972-06-26
SE359825B (en) 1973-09-10
FR2011310A1 (en) 1970-02-27
DE1931197A1 (en) 1970-01-02
IE33375B1 (en) 1974-06-12
IE33375L (en) 1969-12-20
AT291279B (en) 1971-07-12
NL6909085A (en) 1969-12-23

Similar Documents

Publication Publication Date Title
GB1359563A (en) Pyrazolo-pyrimidines useful as xanthine oxidase inhibitors
GB1334348A (en) Fungicidal or bactericidal composition and method
ES368539A1 (en) Procedure for the preparation of new derivatives of paminoalaquil-bencensulfonamida. (Machine-translation by Google Translate, not legally binding)
GB939901A (en) Improvements in or relating to amino pyrazoles
GB1515060A (en) 3-hydroxymethylene-6,7-dimethoxy-2-methyl-4-oxo-1,2,3,4-tetrahydro-1-quinoline carboxylic acid esters
ES343967A1 (en) (trifluoromethyl-phenyl)semicarbazines
GB1377720A (en) Hydroxy pyrimidines
GB769180A (en) Triorganosilyl amino acids
GB1481161A (en) 5-(substituted-benzoyloxy)pyrazoles and a process for their conversion to 4-benzoyl-pyrazole derivatives
GB1417174A (en) 1-2-delta2-imidazolinyl-2,2-diarylcoclopropanes
ES389253A1 (en) 2-substituted phenyl propionic acids
ES329968A1 (en) Procedure for the obtaining of compounds of 3-phenyl-7benzotriazolil-cumarinas of whitening effect. (Machine-translation by Google Translate, not legally binding)
ES449425A1 (en) Aminopyrrole derivatives
ES405648A1 (en) Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding)
GB1264367A (en)
GB1050739A (en)
GB1397807A (en) Process for preparing alpha-keto esters
ES434751A1 (en) Pharmaceutically useful indanylpropionic acid derivatives
ES406132A1 (en) Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding)
ES370226A1 (en) Cycloheptimidazolone derivatives and process for the preparation thereof
ES278796A1 (en) New uracil derivatives and process for their production
GB959807A (en) Improvements in or relating to the fixing of photographic silver halide emulsion layers
GB1049103A (en) Production of 5-isoxazolones and their derivatives
GB1175933A (en)
GB1034613A (en) Improvements in or relating to pyrazolone carboxylic esters