IE33375L - Aminoalkyl benzene sulphonamides - Google Patents

Aminoalkyl benzene sulphonamides

Info

Publication number
IE33375L
IE33375L IE690844A IE84469A IE33375L IE 33375 L IE33375 L IE 33375L IE 690844 A IE690844 A IE 690844A IE 84469 A IE84469 A IE 84469A IE 33375 L IE33375 L IE 33375L
Authority
IE
Ireland
Prior art keywords
acid
sulphonyl
ureas
isocyanate
june
Prior art date
Application number
IE690844A
Other versions
IE33375B1 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IE33375L publication Critical patent/IE33375L/en
Publication of IE33375B1 publication Critical patent/IE33375B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

1,258,594. Sulphonyl-ureas. J. R. GEIGY A.G. 19 June, 1969 [20 June, 1968],. No. 31155/69. Heading C2C. Novel compounds I (including salts with bases and hydrates thereof) wherein m is 2 or 3, R 1 is H or Me and R 2 is H, C 1 to C 6 alkyl or phenyl optionally mono- or disubstituted by halogen, C 1 to C 4 alkyl or C 1 to C 4 alkoxy, or is trifluoromethylphenyl, are obtained by standard methods for sulphonyl-ureas. Octahydro-1,2,4-methenopentalen-5-amine is ob tained by reacting the corresponding 5-isocyanate with glacial acetic acid and acetic anhydride or with an alkanol and hydrolysing the product so obtained; the isocyanate is prepared by treating the corresponding 5-acid hydrazide (prepared by interaction of hydrazine hydrate and the corresponding 5-carboxylic acid-#-ethoxyethyl ester which, in turn is obtained by interaction of acrylic acid-#-ethoxyethyl ester stabilized with hydroquinone monomethyl ether, and 2,5- norbornadiene in the presence of nickel-tricarbonyl triphenylphosphine) with sodium nitrite in the presence of concentrated hydrochloric acid. Pharmaceutical preparations showing hypoglycemic action contain I as active ingredient; administration may be orally or parenterally. [GB1258594A]
IE844/69A 1968-06-20 1969-06-19 Process for the production of new rho-aminoalkyl benzene sulphonamide derivatives IE33375B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH921568A CH499501A (en) 1968-06-20 1968-06-20 Process for the preparation of new derivatives of p-aminoalkyl-benzenesulfonamide

Publications (2)

Publication Number Publication Date
IE33375L true IE33375L (en) 1969-12-20
IE33375B1 IE33375B1 (en) 1974-06-12

Family

ID=4349591

Family Applications (1)

Application Number Title Priority Date Filing Date
IE844/69A IE33375B1 (en) 1968-06-20 1969-06-19 Process for the production of new rho-aminoalkyl benzene sulphonamide derivatives

Country Status (15)

Country Link
AT (1) AT291279B (en)
BE (1) BE734867A (en)
CA (1) CA954531A (en)
CH (2) CH499501A (en)
DE (1) DE1931197A1 (en)
DK (1) DK123472B (en)
ES (2) ES368538A1 (en)
FI (1) FI49960C (en)
FR (1) FR2011310A1 (en)
GB (1) GB1258594A (en)
IE (1) IE33375B1 (en)
IL (1) IL32432A (en)
NL (1) NL6909085A (en)
NO (1) NO125817B (en)
SE (1) SE359825B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1244174C2 (en) * 1965-09-10 1968-01-18 Hoechst Ag Process for the preparation of benzenesulfonylureas

Also Published As

Publication number Publication date
CA954531A (en) 1974-09-10
ES368539A1 (en) 1971-05-01
IL32432A (en) 1973-11-28
GB1258594A (en) 1971-12-30
FI49960C (en) 1975-11-10
BE734867A (en) 1969-12-19
NO125817B (en) 1972-11-06
CH499501A (en) 1970-11-30
CH499502A (en) 1970-11-30
IL32432A0 (en) 1969-08-27
ES368538A1 (en) 1971-05-01
FI49960B (en) 1975-07-31
DK123472B (en) 1972-06-26
SE359825B (en) 1973-09-10
FR2011310A1 (en) 1970-02-27
DE1931197A1 (en) 1970-01-02
IE33375B1 (en) 1974-06-12
AT291279B (en) 1971-07-12
NL6909085A (en) 1969-12-23

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