ES365907A1 - Procedimiento para la preparacion de adriamicina y adriami-cinona. - Google Patents

Procedimiento para la preparacion de adriamicina y adriami-cinona.

Info

Publication number
ES365907A1
ES365907A1 ES365907A ES365907A ES365907A1 ES 365907 A1 ES365907 A1 ES 365907A1 ES 365907 A ES365907 A ES 365907A ES 365907 A ES365907 A ES 365907A ES 365907 A1 ES365907 A1 ES 365907A1
Authority
ES
Spain
Prior art keywords
adriamycin
group
acid
aglycone
alkali
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES365907A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FARMACEUTII ITALIA SOC
Original Assignee
FARMACEUTII ITALIA SOC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FARMACEUTII ITALIA SOC filed Critical FARMACEUTII ITALIA SOC
Publication of ES365907A1 publication Critical patent/ES365907A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES365907A 1968-04-12 1969-04-11 Procedimiento para la preparacion de adriamicina y adriami-cinona. Expired ES365907A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1515968 1968-04-12

Publications (1)

Publication Number Publication Date
ES365907A1 true ES365907A1 (es) 1971-03-16

Family

ID=11146828

Family Applications (1)

Application Number Title Priority Date Filing Date
ES365907A Expired ES365907A1 (es) 1968-04-12 1969-04-11 Procedimiento para la preparacion de adriamicina y adriami-cinona.

Country Status (13)

Country Link
AT (1) AT283597B (xx)
BE (1) BE731398A (xx)
CH (1) CH518250A (xx)
DE (1) DE1917874C3 (xx)
DK (1) DK126987B (xx)
ES (1) ES365907A1 (xx)
FR (1) FR2007443A1 (xx)
GB (1) GB1217133A (xx)
IL (1) IL31966A (xx)
NL (1) NL145536B (xx)
NO (1) NO133271C (xx)
SE (1) SE359293B (xx)
YU (1) YU34389B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160716A1 (en) * 1971-11-23 1973-07-06 Rhone Poulenc Sa Antibiotics duborimycin and 27706rp - by reduction of daunorubicin and adriamycin
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
GB2125030B (en) * 1982-08-13 1986-11-26 Erba Farmitalia Naphthacenequinone synthesis
EP0183691A1 (en) * 1984-06-14 1986-06-11 Biogal Gyogyszergyar Process for preparing adriamycine and halide salts thereof
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
GB2169285A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxydoxorubicin-14-esters
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
JP3112342B2 (ja) * 1992-06-10 2000-11-27 協和醗酵工業株式会社 新規化合物uce6
DE69425356T2 (de) * 1993-09-22 2002-04-18 Hoechst Ag Pro-Prodrugs, ihre Herstellung und Anwendung
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
ES2633359T3 (es) * 2012-03-06 2017-09-20 Tianjin Hemay Oncology Pharmaceutical Co., Ltd. Derivados de antraquinona tetracíclica

Also Published As

Publication number Publication date
SE359293B (xx) 1973-08-27
BE731398A (fr) 1969-10-13
NL6904844A (xx) 1969-10-14
DK126987B (da) 1973-09-10
IL31966A (en) 1972-11-28
DE1917874B2 (de) 1980-02-07
YU34389B (en) 1979-07-10
AT283597B (de) 1970-08-10
NL145536B (nl) 1975-04-15
GB1217133A (en) 1970-12-31
NO133271B (xx) 1975-12-29
DE1917874C3 (de) 1980-10-02
CH518250A (de) 1972-01-31
DE1917874A1 (de) 1969-11-06
YU85869A (en) 1978-12-31
FR2007443A1 (xx) 1970-01-09
NO133271C (xx) 1976-04-07
IL31966A0 (en) 1969-06-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19900227