ES357247A1 - Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina. - Google Patents

Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina.

Info

Publication number
ES357247A1
ES357247A1 ES357247A ES357247A ES357247A1 ES 357247 A1 ES357247 A1 ES 357247A1 ES 357247 A ES357247 A ES 357247A ES 357247 A ES357247 A ES 357247A ES 357247 A1 ES357247 A1 ES 357247A1
Authority
ES
Spain
Prior art keywords
acid addition
addition salt
benzazepine
tetrahydro
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES357247A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES357247A1 publication Critical patent/ES357247A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES357247A 1968-02-09 1968-08-14 Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina. Expired ES357247A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
ES357247A1 true ES357247A1 (es) 1970-03-01

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
ES357247A Expired ES357247A1 (es) 1968-02-09 1968-08-14 Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina.

Country Status (10)

Country Link
AT (1) AT277257B (en))
BE (1) BE719631A (en))
CH (1) CH498122A (en))
DE (1) DE1795132A1 (en))
DK (1) DK123526B (en))
ES (1) ES357247A1 (en))
FR (1) FR1598948A (en))
GB (1) GB1225053A (en))
IL (1) IL30458A (en))
NL (1) NL6811311A (en))

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2207430C3 (de) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CA2529401C (en) 2003-06-17 2015-04-28 Arena Pharmaceuticals, Inc. Processes for preparing 3-benzazepines
EP1633720A1 (en) 2003-06-17 2006-03-15 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
NZ555981A (en) 2004-12-21 2011-01-28 Arena Pharm Inc Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
PT1833473E (pt) 2004-12-23 2009-12-17 Arena Pharm Inc Composições de modulador de receptor 5ht2c e métodos de utilização
EP2471779A1 (en) 2006-04-03 2012-07-04 Arena Pharmaceuticals, Inc. Process for the resolution of a mixture of (R)- and (S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
JP5404414B2 (ja) 2006-12-05 2014-01-29 アリーナ ファーマシューティカルズ， インコーポレイテッド （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンおよびその中間体を調製するための方法
US8822727B2 (en) 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
JP6272695B2 (ja) 2010-09-01 2018-01-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 体重管理のために有用な５−ｈｔ２ｃアゴニストの改変放出剤形
SG188361A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Non-hygroscopic salts of 5-ht2c agonists
EP2939677A1 (en) 2010-09-01 2015-11-04 Arena Pharmaceuticals, Inc. Administration of lorcaserin to indviduals with renal impairment
AU2011296014A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
AR088670A1 (es) 2012-10-09 2014-06-25 Arena Pharm Inc Metodo de control del peso

Also Published As

Publication number Publication date
DE1795132A1 (de) 1972-01-05
IL30458A (en) 1972-03-28
GB1225053A (en) 1971-03-17
AT277257B (de) 1969-12-29
BE719631A (en)) 1969-02-17
NL6811311A (en)) 1969-08-12
IL30458A0 (en) 1968-09-26
FR1598948A (en)) 1970-07-15
DK123526B (da) 1972-07-03
CH498122A (de) 1970-10-31

Similar Documents

Publication Publication Date Title
ES357247A1 (es) Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina.
GB1377231A (en) Basically substituted benzyl-phthalazinone derivatives acid addition salts thereof and process for the production thereof
GB1374367A (en) Propionamide derivative a method of making it and therapeutic compositions containing it
GB1297386A (en))
CH612431A5 (en) Process for the preparation of novel indole derivatives
GB1411583A (en) Aminophenyl-substituted alkyl-heterocyclic derivatives and processes for producing them
GB1481813A (en) Substituted thiazolinylidenyl ketones and their pharmaceutical compositions
GB1448026A (en) 2-aminomethyleneindanone analgesic agents
GB1439724A (en) Berbine derivatives and pharmaceutical compositions containing them
GB1530074A (en) Rho-acetamidophenol derivatives the preparation thereof and the use of such derivatives as therapeutic agents
ES426664A1 (es) Procedimiento para la obtencion de derivados de triazoliso- quinolina.
GB1319489A (en) Tetrahydrocyclopropadibenzapine derivatives
GB1394757A (en) Lysino-calcium chloride
ES293658A1 (es) Procedimiento para la obtenciën de nuevas sulfamidas
GB1201977A (en) Penicilloic acid derivatives and a process for the manufacture thereof
GB1254270A (en) Benzoxazepine derivatives
ES370334A2 (es) Procedimiento para la preparacion de 2,3,4,5-tetrahidro-1h-3-benzacepina.
GB1231613A (en))
GB1434088A (en) N-substituted glycinates a process for their preparation and pharmaceutical compositions containing them
GB1304164A (en))
GB1369888A (en) Substituted amidines
GB1369173A (en) 5-cinnamoyl-pyrrole-2-acetic acids and esters and pharmaceutical compositions containing them
GB1184649A (en) N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them
GB1069717A (en) Improvements in or relating to pyrido[3,4-b]indole derivatives
GB1165099A (en) 2-Aryl-2-Imidazolines