ES340956A1 - Procedimiento para la preparacion de soluciones estables deoxitetraciclina en agua adecuadas para administracion paren-teral, peronal y local. - Google Patents

Procedimiento para la preparacion de soluciones estables deoxitetraciclina en agua adecuadas para administracion paren-teral, peronal y local.

Info

Publication number
ES340956A1
ES340956A1 ES340956A ES340956A ES340956A1 ES 340956 A1 ES340956 A1 ES 340956A1 ES 340956 A ES340956 A ES 340956A ES 340956 A ES340956 A ES 340956A ES 340956 A1 ES340956 A1 ES 340956A1
Authority
ES
Spain
Prior art keywords
oxytetracycline
parenteral
magnesium
preparation
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES340956A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Publication of ES340956A1 publication Critical patent/ES340956A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES340956A 1966-05-31 1967-05-24 Procedimiento para la preparacion de soluciones estables deoxitetraciclina en agua adecuadas para administracion paren-teral, peronal y local. Expired ES340956A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
ES340956A1 true ES340956A1 (es) 1968-06-16

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
ES340956A Expired ES340956A1 (es) 1966-05-31 1967-05-24 Procedimiento para la preparacion de soluciones estables deoxitetraciclina en agua adecuadas para administracion paren-teral, peronal y local.

Country Status (22)

Country Link
US (1) US3557280A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5010373B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT272522B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE699091A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH490087A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS151454B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE1617576C3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK117587B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES340956A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI43622B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR5953M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1131007A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR33861B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL28009A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1140250B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU53788A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY7100015A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL6607516A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO126298B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE354417B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU510986A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU31326B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5418330B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
ES2260051T3 (es) * 1999-09-14 2006-11-01 Trustees Of Tufts College Metodo para preparar tetraciclinas substituidas con quimicas basadas en metales de transicion.
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
WO2001052858A1 (en) 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
WO2001074761A1 (en) 2000-03-31 2001-10-11 Trustees Of Tufts College 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
US6642270B2 (en) * 2000-05-15 2003-11-04 Paratek Pharmaceuticals, Inc. 7-substituted fused ring tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20020128238A1 (en) * 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
WO2002004405A2 (en) 2000-07-07 2002-01-17 Trustees Of Tufts College 13-substituted methacycline compounds
JP5044084B2 (ja) * 2000-07-07 2012-10-10 トラスティーズ・オブ・タフツ・カレッジ 7−置換テトラサイクリン化合物
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
CN1690047B (zh) 2000-07-07 2010-10-06 塔夫茨大学信托人 9-取代的二甲胺四环素化合物
JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ 7、8および9−置換テトラサイクリン化合物
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
EP2301914A1 (en) * 2001-03-13 2011-03-30 Paratek Pharmaceuticals, Inc. 7,9-Substituted tetracycline compounds
EP1379255A2 (en) * 2001-03-14 2004-01-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP1399414B1 (en) 2001-04-24 2010-01-13 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US7056902B2 (en) * 2002-01-08 2006-06-06 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
EP2316450A1 (en) 2002-03-08 2011-05-04 Paratek Pharmaceuticals, Inc. Amino-methyl substituted tetracycline compounds
CN101712632A (zh) 2002-03-21 2010-05-26 帕拉特克药品公司 取代的四环素化合物
CN1700922A (zh) 2002-07-12 2005-11-23 帕拉特克药品公司 3、10或12a位取代的四环素化合物
EP2277504A1 (en) 2002-10-24 2011-01-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
JP2006514119A (ja) * 2003-02-12 2006-04-27 アール アンド ピー コリア カンパニー リミテッド 溶解率が向上した難溶性薬剤の溶媒系
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CA2531732C (en) 2003-07-09 2012-04-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EA200600221A1 (ru) 2003-07-09 2006-06-30 Пэрэтек Фамэсьютикэлс, Инк. Замещённые соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
WO2005070878A1 (en) * 2004-01-15 2005-08-04 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP1805134B1 (en) * 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
EP2295419A3 (en) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US8088755B2 (en) 2005-02-04 2012-01-03 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
JP2009502809A (ja) * 2005-07-21 2009-01-29 パラテック ファーマシューティカルズ インコーポレイテッド 10−置換テトラサイクリンおよびその使用方法
BRPI0617258A2 (pt) * 2005-09-19 2011-07-19 Albemarle Corparation soluções aquosas escoáveis altamente concentradas de ibuprofeno de potássio suas preparações e seus usos
WO2007087416A2 (en) 2006-01-24 2007-08-02 Paratek Pharaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
US7871993B2 (en) * 2006-04-24 2011-01-18 Teva Pharmaceutical Industries Ltd. Tigecycline crystalline forms and processes for preparation thereof
US20080118979A1 (en) * 2006-05-15 2008-05-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
TR201818983T4 (tr) 2006-12-21 2019-01-21 Paratek Pharm Innc İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri
AU2007338747B2 (en) 2006-12-21 2013-12-19 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
AU2008239606A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
US9434680B2 (en) 2007-04-27 2016-09-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
AU2008275701B2 (en) 2007-07-06 2013-04-04 Paratek Pharmaceuticals, Inc. Methods for synthesizing substituted tetracycline compounds
MX2010009693A (es) * 2008-03-05 2010-12-20 Paratek Pharm Innc Compuestos de monociclina y metodos de uso de la misma.
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202216656A (zh) 2008-05-19 2022-05-01 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
CN102099017A (zh) * 2008-07-21 2011-06-15 雅宝公司 高含量布洛芬钠颗粒、其制备及其在制备非泡腾固体剂型中的用途
EP2341771A4 (en) * 2008-09-19 2012-08-15 Paratek Pharm Innc TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED THERAPEUTIC METHODS
AU2010233089B2 (en) 2009-04-10 2016-05-26 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (MMP-1)
ES2739626T3 (es) 2011-05-12 2020-02-03 Paratek Pharm Innc Sales cristalinas de amida del ácido (4S,4aS,5aR,12aS)-4-dimetilamino-3,10,12,12a-tetrahidroxi-7-[(metoxi(metil)amino)-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahidro-naftacen-2-carboxílico y métodos de uso de las mismas
WO2018085216A1 (en) 2016-11-01 2018-05-11 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and use thereof in treating community-acquire bacterial pneumonia (cabp)
JP2020527607A (ja) 2017-07-21 2020-09-10 アルミラール・リミテッド・ライアビリティ・カンパニーAlmirall, Llc 非炎症性病変の処置

Also Published As

Publication number Publication date
NO126298B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-01-22
DE1617576C3 (de) 1980-12-11
CH490087A (de) 1970-05-15
FR5953M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-04-16
DE1617576B2 (de) 1980-04-10
SU510986A3 (ru) 1976-04-15
LU53788A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1967-07-31
IT1140250B (it) 1986-09-24
BE699091A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1967-11-27
JPS5010373B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-04-21
DE1617576A1 (de) 1972-04-27
NL6607516A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1967-12-01
YU31326B (en) 1973-04-30
IL28009A (en) 1970-08-19
CS151454B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-10-19
DK117587B (da) 1970-05-11
US3557280A (en) 1971-01-19
MY7100015A (en) 1971-12-31
AT272522B (de) 1969-07-10
GR33861B (el) 1968-02-09
GB1131007A (en) 1968-10-16
FI43622B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-02-01
SE354417B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-03-12

Similar Documents

Publication Publication Date Title
ES340956A1 (es) Procedimiento para la preparacion de soluciones estables deoxitetraciclina en agua adecuadas para administracion paren-teral, peronal y local.
ES8502873A1 (es) Metodo de preparacion de soluciones para dialisis.
GB1226394A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB1494558A (en) Oxytetracycline solution for parenteral peroral and local administration and processes for the production thereof
ES9300011A1 (es) Un procedimiento para preparar una solucion de cis-platino que contiene acido clarhidrico acuosa estable
ES411801A1 (es) Procedimiento para estabilizar peroxido de hidrogeno.
JPS5639782A (en) Stabilization of thrombin
ES399906A1 (es) Procedimiento para componer preparados colorantes.
ES450075A1 (es) Un metodo de preparacion de derivados de bis-triazinilamino-estilbeno.
ES451256A1 (es) Un metodo para producir una preparacion farmaceutica establepara administracion parenteral.
GB1213808A (en) Photographic processing compositions
ES432208A1 (es) Procedimiento para preparar aglomerados fuertes, estables y de libre fluencia de peroxido de carbonato sodico.
FR2332341B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE33861B1 (en) Stable,water-dispersible ampicillin preparations
GB1427882A (en) Oxytetracycline solutions
JPS5675438A (en) Method for stabilizing aqueous solution of cyanocobalamin
ES357848A1 (es) Procedimiento mejorado para la preparacion de una vacuna contra la poliomielitis.
JPS5211178A (en) Reaction selective activating cathode
GB1438217A (en) 1-alkyl-5-nitro-imidaolyl-2-alkyl-pyridyl compounds and process for preparing them
ES391536A1 (es) Procedimiento para la obtencion de composiciones antibacte-riales.
GB1415453A (en) Composition and process for producing aquarium water having improved properties
ES428798A1 (es) Procedimiento de fabricacion de la metilcobalamina a partir de la cianocobalamina.
GB1361491A (en) Process for the production of oxytetracycline solutions
GB1222449A (en) Process for preparing pure human albumin from solutions containing haemopigments
GB1291678A (en) L-dopa and derivatives

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19880216