ES3009668T3 - Methods and compositions for treatment of angiogenic disorders using anti-vegf agents - Google Patents

Methods and compositions for treatment of angiogenic disorders using anti-vegf agents Download PDF

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Publication number
ES3009668T3
ES3009668T3 ES19744016T ES19744016T ES3009668T3 ES 3009668 T3 ES3009668 T3 ES 3009668T3 ES 19744016 T ES19744016 T ES 19744016T ES 19744016 T ES19744016 T ES 19744016T ES 3009668 T3 ES3009668 T3 ES 3009668T3
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Prior art keywords
vegf
binding
vegfr
treatment
agent
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Active
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ES19744016T
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English (en)
Spanish (es)
Inventor
Napoleone Ferrara
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University of California Berkeley
University of California San Diego UCSD
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University of California Berkeley
University of California San Diego UCSD
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Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F41WEAPONS
    • F41HARMOUR; ARMOURED TURRETS; ARMOURED OR ARMED VEHICLES; MEANS OF ATTACK OR DEFENCE, e.g. CAMOUFLAGE, IN GENERAL
    • F41H5/00Armour; Armour plates
    • F41H5/02Plate construction
    • F41H5/04Plate construction composed of more than one layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES19744016T 2018-01-26 2019-01-25 Methods and compositions for treatment of angiogenic disorders using anti-vegf agents Active ES3009668T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862622382P 2018-01-26 2018-01-26
PCT/US2019/015160 WO2019147944A1 (en) 2018-01-26 2019-01-25 Methods and compositions for treatment of angiogenic disordres using anti-vegf agents

Publications (1)

Publication Number Publication Date
ES3009668T3 true ES3009668T3 (en) 2025-03-31

Family

ID=67395742

Family Applications (1)

Application Number Title Priority Date Filing Date
ES19744016T Active ES3009668T3 (en) 2018-01-26 2019-01-25 Methods and compositions for treatment of angiogenic disorders using anti-vegf agents

Country Status (16)

Country Link
US (3) US11524053B2 (enExample)
EP (2) EP3743091B1 (enExample)
JP (2) JP7517988B2 (enExample)
KR (2) KR102861739B1 (enExample)
CN (2) CN116059318A (enExample)
AU (2) AU2019212622B2 (enExample)
BR (1) BR112020015074A2 (enExample)
CO (1) CO2020010384A2 (enExample)
DK (1) DK3743091T3 (enExample)
EA (1) EA202091786A1 (enExample)
ES (1) ES3009668T3 (enExample)
FI (1) FI3743091T3 (enExample)
IL (2) IL310376B2 (enExample)
MX (1) MX2021001424A (enExample)
SG (1) SG11202007130RA (enExample)
WO (1) WO2019147944A1 (enExample)

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KR20250052466A (ko) 2025-04-18
EP3743091A4 (en) 2021-12-15
KR102861739B1 (ko) 2025-09-22
US12514905B2 (en) 2026-01-06
MX2021001424A (es) 2021-06-23
IL310376B1 (en) 2025-10-01
IL276158B1 (en) 2024-03-01
NZ766484A (en) 2025-08-29
FI3743091T3 (fi) 2025-01-03
WO2019147944A8 (en) 2020-08-20
CN111741761B (zh) 2023-04-18
BR112020015074A2 (pt) 2020-12-08
EP3743091B1 (en) 2024-11-06
EP4495136A2 (en) 2025-01-22
JP2021511061A (ja) 2021-05-06
EP3743091A1 (en) 2020-12-02
DK3743091T3 (da) 2025-01-06
CN111741761A (zh) 2020-10-02
CA3089481A1 (en) 2019-08-01
EA202091786A1 (ru) 2020-10-20
CO2020010384A2 (es) 2020-12-10
IL276158A (en) 2020-09-30
US20240366721A1 (en) 2024-11-07
AU2024204947A1 (en) 2024-08-08
IL310376B2 (en) 2026-02-01
JP7517988B2 (ja) 2024-07-17
US20260097098A1 (en) 2026-04-09
AU2019212622A1 (en) 2020-08-13
JP2024149493A (ja) 2024-10-18
SG11202007130RA (en) 2020-08-28
KR20200112893A (ko) 2020-10-05
CN116059318A (zh) 2023-05-05
US20200353041A1 (en) 2020-11-12
WO2019147944A1 (en) 2019-08-01
IL310376A (en) 2024-03-01
AU2019212622B2 (en) 2024-05-23
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