ES2995959T3 - Methods for the detection and treatment of lung cancer - Google Patents

Methods for the detection and treatment of lung cancer Download PDF

Info

Publication number
ES2995959T3
ES2995959T3 ES18752036T ES18752036T ES2995959T3 ES 2995959 T3 ES2995959 T3 ES 2995959T3 ES 18752036 T ES18752036 T ES 18752036T ES 18752036 T ES18752036 T ES 18752036T ES 2995959 T3 ES2995959 T3 ES 2995959T3
Authority
ES
Spain
Prior art keywords
lung cancer
sftpb
pro
cea
cyfra21
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18752036T
Other languages
English (en)
Spanish (es)
Inventor
Samir Hanash
Ayumu Taguchi
Ziding Feng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
University of Texas at Austin
Original Assignee
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, University of Texas at Austin filed Critical University of Texas System
Application granted granted Critical
Publication of ES2995959T3 publication Critical patent/ES2995959T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20Probabilistic models
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Probability & Statistics with Applications (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
ES18752036T 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer Active ES2995959T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762456731P 2017-02-09 2017-02-09
PCT/US2018/017704 WO2018148600A1 (en) 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer

Publications (1)

Publication Number Publication Date
ES2995959T3 true ES2995959T3 (en) 2025-02-11

Family

ID=63107741

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18752036T Active ES2995959T3 (en) 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer

Country Status (8)

Country Link
US (1) US12405274B2 (enExample)
EP (2) EP3580560B1 (enExample)
JP (1) JP7311417B2 (enExample)
KR (2) KR102630885B1 (enExample)
CN (2) CN117368475A (enExample)
CA (1) CA3053116A1 (enExample)
ES (1) ES2995959T3 (enExample)
WO (1) WO2018148600A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102630885B1 (ko) 2017-02-09 2024-01-29 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 폐암의 검출 및 치료 방법
US20220260573A1 (en) * 2019-07-29 2022-08-18 Biomark Cancer Systems Inc. Method of discriminating lung cancer patients
US20230213521A1 (en) * 2020-04-28 2023-07-06 Luxembourg Institute Of Health (Lih) Biomarkers for detection of lung cancer
CA3191405A1 (en) * 2020-09-01 2022-03-10 Ali Ya KHAMMANIVONG Predictive diagnostic test for early detection and monitoring of diseases
CN112147099A (zh) * 2020-09-22 2020-12-29 范庆坤 一种m蛋白紫外分光检测法
EP4222287A4 (en) * 2020-10-02 2024-12-18 Board of Regents, The University of Texas System METHODS FOR THE DETECTION AND TREATMENT OF LUNG CANCER
EP4357782A1 (en) * 2022-10-18 2024-04-24 MU Bioteknik Aktiebolag Protein biomarker panel for the diagnosis of colorectal cancer
CN115575636B (zh) * 2022-11-22 2023-04-04 杭州广科安德生物科技有限公司 一种用于肺癌检测的生物标志物及其系统
CN116593702B (zh) * 2023-05-11 2024-04-05 杭州广科安德生物科技有限公司 一种肺癌的生物标志物以及诊断系统
CN118983078B (zh) * 2024-08-15 2025-03-25 立本医疗器械(成都)有限公司 基于ptr-tof-ms的肺癌筛查模型构建方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2610806T3 (es) 2005-12-22 2017-05-03 Abbott Molecular Inc. Métodos y combinaciones de marcadores para la detección de la predisposición al cáncer de pulmón
US20080133141A1 (en) * 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
EP2153232A1 (en) * 2007-05-18 2010-02-17 Duke University Serum biomarkers for the early detection of lung cancer
CA2798441A1 (en) * 2010-05-07 2011-11-10 Abbvie Inc. Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
US20120087860A1 (en) * 2010-05-24 2012-04-12 Marek Malecki Methods for in vivo cancer detection, diagnosis and therapy using multidomain biotags
US20130078642A1 (en) 2010-06-03 2013-03-28 Porto Conte Richerche S.R.L. Biomarkers for lung neuroendocrine tumors
CN102321760A (zh) * 2011-08-26 2012-01-18 泸州医学院附属医院 一种非小细胞肺癌标志物及应用
US9753043B2 (en) * 2011-12-18 2017-09-05 20/20 Genesystems, Inc. Methods and algorithms for aiding in the detection of cancer
US20140271453A1 (en) * 2013-03-14 2014-09-18 Abbott Laboratories Methods for the early detection of lung cancer
US9753037B2 (en) 2013-03-15 2017-09-05 Rush University Medical Center Biomarker panel for detecting lung cancer
US20150072890A1 (en) * 2013-09-11 2015-03-12 20/20 Gene Systems, Inc. Methods and compositions for aiding in the detection of lung cancer
US20160060329A1 (en) 2014-07-28 2016-03-03 Donald SIN Compositions and methods for the diagnosis and prognosis of lung cancer
CA3029063C (en) 2015-06-26 2023-09-05 Biomark Cancer Systems Inc. Method of detecting lung cancer
JP6903672B2 (ja) 2016-03-08 2021-07-14 マグアレイ,インコーポレイテッド 肺癌の診断および治療のための蛋白質と自己抗体バイオマーカー
CN105717146B (zh) * 2016-03-29 2018-11-09 复旦大学附属中山医院 一种基于ct影像及生物标志物谱针对中国城市人口高危人群的肺癌风险预测试剂盒
KR102630885B1 (ko) 2017-02-09 2024-01-29 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 폐암의 검출 및 치료 방법
EP4222287A4 (en) * 2020-10-02 2024-12-18 Board of Regents, The University of Texas System METHODS FOR THE DETECTION AND TREATMENT OF LUNG CANCER

Also Published As

Publication number Publication date
US12405274B2 (en) 2025-09-02
US20230314436A1 (en) 2023-10-05
EP4528741A3 (en) 2025-04-09
KR102827354B1 (ko) 2025-06-30
KR102630885B1 (ko) 2024-01-29
WO2018148600A1 (en) 2018-08-16
EP3580560B1 (en) 2024-10-02
EP3580560A1 (en) 2019-12-18
EP3580560A4 (en) 2020-12-09
US20200025766A1 (en) 2020-01-23
JP2020510816A (ja) 2020-04-09
EP4528741A2 (en) 2025-03-26
JP7311417B2 (ja) 2023-07-19
KR20190116368A (ko) 2019-10-14
CN117368475A (zh) 2024-01-09
CN110291397A (zh) 2019-09-27
KR20240015172A (ko) 2024-02-02
CA3053116A1 (en) 2018-08-16

Similar Documents

Publication Publication Date Title
ES2995959T3 (en) Methods for the detection and treatment of lung cancer
Hollevoet et al. Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis
Zhang et al. The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in lung cancer patients
Rho et al. Protein and glycomic plasma markers for early detection of adenoma and colon cancer
Nguyen et al. Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival
Filella et al. Clinical usefulness of circulating tumor markers
Amonkar et al. Development and preliminary evaluation of a multivariate index assay for ovarian cancer
Haab et al. Definitive characterization of CA 19-9 in resectable pancreatic cancer using a reference set of serum and plasma specimens
Greillier et al. Biomarkers for malignant pleural mesothelioma: current status
Giessen et al. Evaluation of preoperative serum markers for individual patient prognosis in stage I–III rectal cancer
Hsu et al. Serum markers of CYFRA 21-1 and C-reactive proteins in oral squamous cell carcinoma
Moore et al. Current clinical use of biomarkers for epithelial ovarian cancer
van Veenendaal Linde et al. The clinical utility of neuron-specific enolase (NSE) serum levels as a biomarker for Merkel cell carcinoma (MCC)
Topuz et al. Circulating calprotectin as a biomarker of laryngeal carcinoma
Di Noia et al. Blood serum amyloid A as potential biomarker of pembrolizumab efficacy for patients affected by advanced non-small cell lung cancer overexpressing PD-L1: results of the exploratory “FoRECATT” study
Fatela-Cantillo et al. Prognostic value of plasmatic tumor M2 pyruvate kinase and carcinoembryonic antigen in the survival of colorectal cancer patients
Wang et al. The role of autoantibody detection in the diagnosis and staging of lung cancer
Sarejloo et al. Diagnostic and prognostic role of NLR in testicular cancer
JP2021144052A (ja) マーカー、ヒト精巣上体タンパク質4(he4)に基づく肺腺癌の再発を検出する方法および関連する使用
Xie et al. Grading carcinoembryonic antigen levels can enhance the effectiveness of prognostic stratification in patients with colorectal cancer: a single-centre retrospective study
Jannawan et al. High level of serum coiled-coil domain containing 25 (CCDC25) as a diagnostic marker for cholangiocarcinoma but not for other cancers
WO2024107923A1 (en) Methods for the detection and treatment of lung cancer
Wang et al. STK1p as a prognostic biomarker for overall survival in non-small-cell lung carcinoma, based on real-world data
US12504430B2 (en) Methods for the detection and treatment of lung cancer
Mayasari et al. Correlation of CD 133 biomarker with outcomes and therapy response in advanced-stage non-small cell lung carcinoma