CA3053116A1 - Methods for the detection and treatment of lung cancer - Google Patents

Methods for the detection and treatment of lung cancer Download PDF

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Publication number
CA3053116A1
CA3053116A1 CA3053116A CA3053116A CA3053116A1 CA 3053116 A1 CA3053116 A1 CA 3053116A1 CA 3053116 A CA3053116 A CA 3053116A CA 3053116 A CA3053116 A CA 3053116A CA 3053116 A1 CA3053116 A1 CA 3053116A1
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Canada
Prior art keywords
antigen
lung cancer
sftpb
subject
pro
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3053116A
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English (en)
French (fr)
Inventor
Samir Hanash
Ayumu Taguchi
Ziding FENG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
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Application filed by University of Texas System filed Critical University of Texas System
Publication of CA3053116A1 publication Critical patent/CA3053116A1/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20Probabilistic models
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Physiology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
CA3053116A 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer Pending CA3053116A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762456731P 2017-02-09 2017-02-09
US62/456,731 2017-02-09
PCT/US2018/017704 WO2018148600A1 (en) 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer

Publications (1)

Publication Number Publication Date
CA3053116A1 true CA3053116A1 (en) 2018-08-16

Family

ID=63107741

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3053116A Pending CA3053116A1 (en) 2017-02-09 2018-02-09 Methods for the detection and treatment of lung cancer

Country Status (8)

Country Link
US (1) US12405274B2 (enExample)
EP (2) EP3580560B1 (enExample)
JP (1) JP7311417B2 (enExample)
KR (2) KR102827354B1 (enExample)
CN (2) CN110291397A (enExample)
CA (1) CA3053116A1 (enExample)
ES (1) ES2995959T3 (enExample)
WO (1) WO2018148600A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2995959T3 (en) 2017-02-09 2025-02-11 Univ Texas Methods for the detection and treatment of lung cancer
CA3146120A1 (en) * 2019-07-29 2021-02-04 Rashid BUX Method of discriminating lung cancer patients
JP2023531860A (ja) * 2020-04-28 2023-07-26 ルクセンブルク インスティテュート オブ ヘルス(エルアイエイチ) 肺癌検出用バイオマーカー
JP2023541718A (ja) * 2020-09-01 2023-10-03 オンコデア・コーポレーション 病気の早期検出および監視のための予測診断検査
CN112147099A (zh) * 2020-09-22 2020-12-29 范庆坤 一种m蛋白紫外分光检测法
KR20230080442A (ko) * 2020-10-02 2023-06-07 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 폐암의 검출 및 치료를 위한 방법
EP4357782A1 (en) * 2022-10-18 2024-04-24 MU Bioteknik Aktiebolag Protein biomarker panel for the diagnosis of colorectal cancer
CN116559453A (zh) * 2022-11-22 2023-08-08 杭州广科安德生物科技有限公司 一种用于肺癌检测的生物标志物
CN118937675A (zh) * 2023-05-11 2024-11-12 杭州广科安德生物科技有限公司 一种肺癌的生物标志物以及诊断系统
CN118983078B (zh) * 2024-08-15 2025-03-25 立本医疗器械(成都)有限公司 基于ptr-tof-ms的肺癌筛查模型构建方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2949753A1 (en) * 2005-12-22 2007-07-05 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20080133141A1 (en) * 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
CA2681667A1 (en) 2007-05-18 2008-11-27 Duke University Serum biomarkers for the early detection of lung cancer
EP2567232A1 (en) 2010-05-07 2013-03-13 AbbVie Inc. Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
US20120093733A1 (en) * 2010-05-24 2012-04-19 Marek Malecki Multidomain biotags for cancer detection, diagnosis and therapy and methods of their use
US20130078642A1 (en) 2010-06-03 2013-03-28 Porto Conte Richerche S.R.L. Biomarkers for lung neuroendocrine tumors
CN102321760A (zh) * 2011-08-26 2012-01-18 泸州医学院附属医院 一种非小细胞肺癌标志物及应用
US9753043B2 (en) 2011-12-18 2017-09-05 20/20 Genesystems, Inc. Methods and algorithms for aiding in the detection of cancer
US20140271453A1 (en) * 2013-03-14 2014-09-18 Abbott Laboratories Methods for the early detection of lung cancer
US9753037B2 (en) * 2013-03-15 2017-09-05 Rush University Medical Center Biomarker panel for detecting lung cancer
US20150072890A1 (en) 2013-09-11 2015-03-12 20/20 Gene Systems, Inc. Methods and compositions for aiding in the detection of lung cancer
US20160060329A1 (en) * 2014-07-28 2016-03-03 Donald SIN Compositions and methods for the diagnosis and prognosis of lung cancer
US11656229B2 (en) * 2015-06-26 2023-05-23 Biomark Cancer Systems Inc. Method of detecting lung cancer
EP3427051B1 (en) 2016-03-08 2021-06-16 Magarray, Inc. Protein and autoantibody biomarkers for the diagnosis and treatment of lung cancer
CN105717146B (zh) * 2016-03-29 2018-11-09 复旦大学附属中山医院 一种基于ct影像及生物标志物谱针对中国城市人口高危人群的肺癌风险预测试剂盒
ES2995959T3 (en) 2017-02-09 2025-02-11 Univ Texas Methods for the detection and treatment of lung cancer
KR20230080442A (ko) * 2020-10-02 2023-06-07 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 폐암의 검출 및 치료를 위한 방법

Also Published As

Publication number Publication date
KR102630885B1 (ko) 2024-01-29
CN110291397A (zh) 2019-09-27
KR20190116368A (ko) 2019-10-14
CN117368475A (zh) 2024-01-09
EP4528741A2 (en) 2025-03-26
ES2995959T3 (en) 2025-02-11
US12405274B2 (en) 2025-09-02
WO2018148600A1 (en) 2018-08-16
US20230314436A1 (en) 2023-10-05
KR102827354B1 (ko) 2025-06-30
JP2020510816A (ja) 2020-04-09
JP7311417B2 (ja) 2023-07-19
EP3580560A4 (en) 2020-12-09
EP3580560A1 (en) 2019-12-18
EP4528741A3 (en) 2025-04-09
EP3580560B1 (en) 2024-10-02
KR20240015172A (ko) 2024-02-02
US20200025766A1 (en) 2020-01-23

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