ES2981607T3 - Activadores de Tie-2 para uso en el tratamiento de la presión intraocular - Google Patents

Activadores de Tie-2 para uso en el tratamiento de la presión intraocular Download PDF

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Publication number
ES2981607T3
ES2981607T3 ES21191499T ES21191499T ES2981607T3 ES 2981607 T3 ES2981607 T3 ES 2981607T3 ES 21191499 T ES21191499 T ES 21191499T ES 21191499 T ES21191499 T ES 21191499T ES 2981607 T3 ES2981607 T3 ES 2981607T3
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ES21191499T
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English (en)
Spanish (es)
Inventor
Kevin Gene Peters
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Eyepoint Pharmaceuticals Inc
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Eyepoint Pharmaceuticals Inc
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES21191499T 2015-09-23 2016-09-22 Activadores de Tie-2 para uso en el tratamiento de la presión intraocular Active ES2981607T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562222481P 2015-09-23 2015-09-23

Publications (1)

Publication Number Publication Date
ES2981607T3 true ES2981607T3 (es) 2024-10-09

Family

ID=58276474

Family Applications (2)

Application Number Title Priority Date Filing Date
ES21191499T Active ES2981607T3 (es) 2015-09-23 2016-09-22 Activadores de Tie-2 para uso en el tratamiento de la presión intraocular
ES16849594T Active ES2894802T3 (es) 2015-09-23 2016-09-22 Activadores de Tie-2 para su uso en el tratamiento de la presión intraocular

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES16849594T Active ES2894802T3 (es) 2015-09-23 2016-09-22 Activadores de Tie-2 para su uso en el tratamiento de la presión intraocular

Country Status (15)

Country Link
US (3) US10952992B2 (enExample)
EP (3) EP3352856B1 (enExample)
JP (3) JP6959924B2 (enExample)
KR (1) KR20180054677A (enExample)
CN (2) CN108290057A (enExample)
AU (2) AU2016326510C1 (enExample)
BR (1) BR112018005499A2 (enExample)
CA (1) CA2998673C (enExample)
ES (2) ES2981607T3 (enExample)
IL (1) IL258150B (enExample)
MX (2) MX387804B (enExample)
MY (1) MY194736A (enExample)
PH (1) PH12018500658A1 (enExample)
SG (1) SG10201912000WA (enExample)
WO (1) WO2017053566A1 (enExample)

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Also Published As

Publication number Publication date
PH12018500658A1 (en) 2018-10-01
JP6959924B2 (ja) 2021-11-05
EP3352856B1 (en) 2021-08-18
MX387804B (es) 2025-03-19
US12171751B2 (en) 2024-12-24
EP4414032A3 (en) 2024-11-06
EP3352856A4 (en) 2019-05-01
BR112018005499A2 (pt) 2018-10-09
SG10201912000WA (en) 2020-02-27
US20210386713A1 (en) 2021-12-16
IL258150A (en) 2018-05-31
AU2016326510A1 (en) 2018-04-12
EP4414032A2 (en) 2024-08-14
MX2021010915A (es) 2021-10-01
AU2022202618B2 (en) 2023-12-14
CA2998673A1 (en) 2017-03-30
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WO2017053566A1 (en) 2017-03-30
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MY194736A (en) 2022-12-15
US20170079959A1 (en) 2017-03-23
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EP3352856A1 (en) 2018-08-01
MX2018003542A (es) 2018-11-09
KR20180054677A (ko) 2018-05-24
CN108290057A (zh) 2018-07-17
NZ780430A (en) 2024-09-27
EP3977994B1 (en) 2024-04-24
AU2022202618A1 (en) 2022-05-12
AU2016326510B2 (en) 2022-03-10
US10952992B2 (en) 2021-03-23
CN113713101B (zh) 2023-07-28
IL258150B (en) 2021-06-30
NZ740730A (en) 2024-07-26
EP3977994C0 (en) 2024-04-24
CA2998673C (en) 2023-12-12
US20230398100A1 (en) 2023-12-14
AU2016326510C1 (en) 2024-06-27
CN113713101A (zh) 2021-11-30
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JP2018528273A (ja) 2018-09-27
JP2024061772A (ja) 2024-05-08

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