ES2962612T3 - Dispositivo para suministrar composiciones de hidrogel con autopurgado para prevenir obstrucciones - Google Patents
Dispositivo para suministrar composiciones de hidrogel con autopurgado para prevenir obstrucciones Download PDFInfo
- Publication number
- ES2962612T3 ES2962612T3 ES19189931T ES19189931T ES2962612T3 ES 2962612 T3 ES2962612 T3 ES 2962612T3 ES 19189931 T ES19189931 T ES 19189931T ES 19189931 T ES19189931 T ES 19189931T ES 2962612 T3 ES2962612 T3 ES 2962612T3
- Authority
- ES
- Spain
- Prior art keywords
- valve
- path
- channel
- purge
- pressure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000010926 purge Methods 0.000 title claims abstract description 58
- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 239000000017 hydrogel Substances 0.000 title abstract description 28
- 239000007788 liquid Substances 0.000 claims abstract description 49
- 238000002156 mixing Methods 0.000 claims abstract description 15
- 230000004044 response Effects 0.000 claims description 9
- 238000011144 upstream manufacturing Methods 0.000 claims description 9
- 238000005406 washing Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 description 19
- 239000007921 spray Substances 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000012530 fluid Substances 0.000 description 8
- 238000001879 gelation Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 230000009977 dual effect Effects 0.000 description 4
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 102000009027 Albumins Human genes 0.000 description 2
- 108010088751 Albumins Proteins 0.000 description 2
- 239000011344 liquid material Substances 0.000 description 2
- 230000000269 nucleophilic effect Effects 0.000 description 2
- -1 poly(ethylene glycol) Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 239000000565 sealant Substances 0.000 description 2
- 208000031737 Tissue Adhesions Diseases 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000012460 protein solution Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
- A61B17/12186—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
- A61M5/003—Kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00942—Material properties hydrophilic
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Surgical Instruments (AREA)
- Accessories For Mixers (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32090910P | 2010-04-05 | 2010-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2962612T3 true ES2962612T3 (es) | 2024-03-20 |
Family
ID=44710505
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19189931T Active ES2962612T3 (es) | 2010-04-05 | 2011-04-05 | Dispositivo para suministrar composiciones de hidrogel con autopurgado para prevenir obstrucciones |
| ES11766576T Active ES2755034T3 (es) | 2010-04-05 | 2011-04-05 | Sistemas, dispositivos y métodos para administrar composiciones de hidrogel con autopurgado para impedir la obstrucción |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11766576T Active ES2755034T3 (es) | 2010-04-05 | 2011-04-05 | Sistemas, dispositivos y métodos para administrar composiciones de hidrogel con autopurgado para impedir la obstrucción |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8641662B2 (enExample) |
| EP (2) | EP2555812B1 (enExample) |
| JP (1) | JP5833099B2 (enExample) |
| CN (1) | CN102917736A (enExample) |
| BR (1) | BR112012025500A2 (enExample) |
| CA (1) | CA2795260C (enExample) |
| ES (2) | ES2962612T3 (enExample) |
| WO (1) | WO2011127020A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9498271B2 (en) * | 2009-10-29 | 2016-11-22 | Cook Medical Technologies Llc | Coaxial needle cannula with distal spiral mixer and side ports for fluid injection |
| EP2555812B1 (en) * | 2010-04-05 | 2019-09-04 | Neomend, Inc. | Systems, devices, methods for delivering hydrogel compositions with self-purging to prevent clogging |
| US9499390B1 (en) * | 2012-07-17 | 2016-11-22 | Global Agricultural Technology And Engineering, Llc | Liquid delivery system |
| WO2014160083A1 (en) | 2013-03-13 | 2014-10-02 | Applied Cardiovascular Solutions, Llc. | Methods, compositions, and devices for the occlusion of cavities and passageways |
| WO2015034870A2 (en) * | 2013-09-03 | 2015-03-12 | Arocha Max | Double-chamber mixing syringe and method of use |
| US10952709B2 (en) | 2014-04-04 | 2021-03-23 | Hyperbranch Medical Technology, Inc. | Extended tip spray applicator for two-component surgical sealant, and methods of use thereof |
| GB2528808B (en) | 2014-06-05 | 2016-12-07 | Cook Medical Technologies Llc | Apparatus for delivering filamentary material into a patient |
| GB2526863B (en) * | 2014-06-05 | 2017-02-08 | Cook Medical Technologies Llc | Apparatus for delivering filamentary material into a patient |
| US9993253B2 (en) | 2014-06-05 | 2018-06-12 | Cook Medical Technologies Llc | Dispensing device and method for delivering filamentary material into a patient |
| US9867623B2 (en) | 2014-06-05 | 2018-01-16 | Cook Medical Technologies Llc | Apparatus for delivering filamentary material into a patient |
| CN104258749B (zh) * | 2014-09-02 | 2016-08-24 | 山东问清环境科技有限公司 | 洗涤剂快速稀释器 |
| JP2017177073A (ja) * | 2016-03-31 | 2017-10-05 | テルモ株式会社 | 塗布具 |
| CN110870940A (zh) * | 2018-09-04 | 2020-03-10 | 上海叁钛生物科技有限公司 | 皮肤原位打印用打印头装置 |
| CN109771810B (zh) * | 2019-03-25 | 2021-06-15 | 南通市第一人民医院 | 一种烧伤科用去疤痕涂药装置及其涂药方法 |
| CA3150246A1 (en) * | 2019-09-05 | 2021-03-11 | Elizabeth COSSGRIFF-HERNANDEZ | Electrically conductive hydrogels usable as lead extensions, apparatus for delivery of a hydrogel into the vasculasture, and methods of treating ventricular arrhythmia with electrically conductive hydrogels injected in the venous system |
| FR3105004B1 (fr) * | 2019-12-18 | 2023-10-27 | Univ Bordeaux | Cathéter pour l’administration d’une pulverisation médicamenteuse dans la trachée d’un sujet |
| CN112023240B (zh) * | 2020-09-14 | 2021-03-12 | 广州海研生物科技有限公司 | 一种生物喷头组件 |
| WO2022068893A1 (zh) * | 2020-09-30 | 2022-04-07 | 广州迈普再生医学科技股份有限公司 | 医用胶喷涂装置 |
| EP4104887A1 (en) * | 2021-06-11 | 2022-12-21 | Cook Medical Technologies LLC | Delivery system with dual lumen catheter |
| US12409271B2 (en) | 2022-04-25 | 2025-09-09 | Frank Levy | Apparatus and method for producing an enriched medical suspension |
| US20250332346A1 (en) * | 2024-04-25 | 2025-10-30 | Boston Scientific Scimed, Inc. | Improved delivery devices |
| JP7782875B1 (ja) * | 2024-06-24 | 2025-12-09 | 竹本油脂株式会社 | 混練装置及び混練物の製造方法 |
| CN119258381B (zh) * | 2024-11-04 | 2025-09-23 | 暨南大学 | 一种可调力度的骨蜡涂抹枪 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2429407A1 (fr) * | 1978-06-19 | 1980-01-18 | Bodet Fabrice | Perfectionnements aux balles pour armes a feu |
| AT379311B (de) * | 1984-03-29 | 1985-12-27 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes |
| US4819653A (en) * | 1986-04-11 | 1989-04-11 | Lloyd A. Marks | Multi-function fluid communication control system |
| US5163584A (en) * | 1990-12-18 | 1992-11-17 | Polyfoam Products, Inc. | Method and apparatus for mixing and dispensing foam with injected low pressure gas |
| US5522804A (en) * | 1994-02-15 | 1996-06-04 | Lynn; Lawrence A. | Aspiration, mixing, and injection syringe |
| US6033401A (en) | 1997-03-12 | 2000-03-07 | Advanced Closure Systems, Inc. | Vascular sealing device with microwave antenna |
| WO1996039212A2 (en) * | 1995-06-06 | 1996-12-12 | Quantic Biomedical Partners | Wound sealant preparation and application device and method |
| US6613020B1 (en) | 1996-12-06 | 2003-09-02 | Bristol-Myers Squibb Company | Method of applying a mixture of two liquid components as well as a device for carrying out the method |
| US6743248B2 (en) | 1996-12-18 | 2004-06-01 | Neomend, Inc. | Pretreatment method for enhancing tissue adhesion |
| DE19709896C1 (de) * | 1997-03-11 | 1998-12-24 | Omrix Biopharm Sa | Applikator zum Auftragen eines Ein- oder Mehrkomponenten-Fluids und Verfahren zum Aufsprühen eines derartigen Fluids |
| US6371975B2 (en) | 1998-11-06 | 2002-04-16 | Neomend, Inc. | Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers |
| US6733515B1 (en) | 1997-03-12 | 2004-05-11 | Neomend, Inc. | Universal introducer |
| US6183444B1 (en) * | 1998-05-16 | 2001-02-06 | Microheart, Inc. | Drug delivery module |
| EP1085925B1 (en) * | 1998-05-21 | 2007-07-18 | Baxter International Inc. | Sealant applicator and method employing impulse clearing |
| US6152943A (en) | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
| US6179862B1 (en) * | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| US6458147B1 (en) | 1998-11-06 | 2002-10-01 | Neomend, Inc. | Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue |
| US6994686B2 (en) * | 1998-08-26 | 2006-02-07 | Neomend, Inc. | Systems for applying cross-linked mechanical barriers |
| AU6151799A (en) * | 1998-09-17 | 2000-04-03 | Focal, Inc. | Self-cleaning fluid delivery device for medical applications |
| US6830756B2 (en) * | 1998-11-06 | 2004-12-14 | Neomend, Inc. | Systems, methods, and compositions for achieving closure of vascular puncture sites |
| US20030209612A1 (en) | 2000-07-17 | 2003-11-13 | Kevin Hahnen | Spray head for applying a multi-component mixture |
| US6852099B2 (en) * | 2002-06-04 | 2005-02-08 | Baxter International Inc. | Device for controllably applying liquids to body surfaces |
| JP2004135907A (ja) * | 2002-10-18 | 2004-05-13 | Nipro Corp | 薬液注入器具 |
| WO2005007223A2 (en) * | 2003-07-16 | 2005-01-27 | Sasha John | Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations |
| CN101175517A (zh) * | 2005-05-16 | 2008-05-07 | 马林克罗特公司 | 具有一体化管路的多筒注射器 |
| WO2007059801A1 (en) * | 2005-11-22 | 2007-05-31 | Omrix Biopharmaceuticals S.A. | Applicator device for applying a multi-component fluid |
| JP4360377B2 (ja) * | 2006-02-22 | 2009-11-11 | 住友ベークライト株式会社 | 生体組織接着剤塗布用具 |
| US7837656B2 (en) | 2006-03-27 | 2010-11-23 | Tyco Healthcare Group Lp | Dual air regulated spray applicator |
| US20080166292A1 (en) * | 2007-01-01 | 2008-07-10 | Medrad, Inc. | Pharmaceutical Dosing Method |
| US8057426B2 (en) * | 2007-01-03 | 2011-11-15 | Medtronic Vascular, Inc. | Devices and methods for injection of multiple-component therapies |
| JP2009011805A (ja) * | 2007-02-09 | 2009-01-22 | Terumo Corp | 塗布具 |
| US8545433B2 (en) * | 2008-04-03 | 2013-10-01 | V.V.T. Med Ltd. | Apparatus and method for treating spider veins |
| JP5805542B2 (ja) * | 2009-02-20 | 2015-11-04 | オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． | 少なくとも２成分の薬物を投与する装置 |
| WO2010129747A1 (en) * | 2009-05-06 | 2010-11-11 | Synthes Usa, Llc | Method and apparatus for applying a sealant |
| US10987093B2 (en) * | 2010-04-05 | 2021-04-27 | Neomend, Inc. | Method and apparatus for wound sealant application |
| EP2555812B1 (en) * | 2010-04-05 | 2019-09-04 | Neomend, Inc. | Systems, devices, methods for delivering hydrogel compositions with self-purging to prevent clogging |
| JP5792452B2 (ja) * | 2010-11-10 | 2015-10-14 | 住友ベークライト株式会社 | 生体組織接着剤塗布用具 |
-
2011
- 2011-04-05 EP EP11766576.0A patent/EP2555812B1/en active Active
- 2011-04-05 JP JP2013503827A patent/JP5833099B2/ja active Active
- 2011-04-05 CN CN2011800274631A patent/CN102917736A/zh active Pending
- 2011-04-05 US US13/080,054 patent/US8641662B2/en active Active
- 2011-04-05 ES ES19189931T patent/ES2962612T3/es active Active
- 2011-04-05 WO PCT/US2011/031192 patent/WO2011127020A2/en not_active Ceased
- 2011-04-05 ES ES11766576T patent/ES2755034T3/es active Active
- 2011-04-05 EP EP19189931.9A patent/EP3590567B1/en active Active
- 2011-04-05 BR BR112012025500A patent/BR112012025500A2/pt not_active Application Discontinuation
- 2011-04-05 CA CA2795260A patent/CA2795260C/en active Active
-
2014
- 2014-02-03 US US14/170,759 patent/US9662098B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140148791A1 (en) | 2014-05-29 |
| ES2755034T3 (es) | 2020-04-21 |
| CA2795260C (en) | 2017-05-09 |
| EP3590567C0 (en) | 2023-10-04 |
| US8641662B2 (en) | 2014-02-04 |
| EP2555812A2 (en) | 2013-02-13 |
| EP3590567B1 (en) | 2023-10-04 |
| US9662098B2 (en) | 2017-05-30 |
| JP5833099B2 (ja) | 2015-12-16 |
| CN102917736A (zh) | 2013-02-06 |
| WO2011127020A3 (en) | 2012-03-08 |
| CA2795260A1 (en) | 2011-10-13 |
| JP2013523335A (ja) | 2013-06-17 |
| US20110245803A1 (en) | 2011-10-06 |
| EP3590567A1 (en) | 2020-01-08 |
| EP2555812B1 (en) | 2019-09-04 |
| WO2011127020A2 (en) | 2011-10-13 |
| EP2555812A4 (en) | 2017-09-20 |
| BR112012025500A2 (pt) | 2016-06-21 |
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