ES2926463T3 - Activación de la bioluminiscencia mediante complementación estructural - Google Patents

Activación de la bioluminiscencia mediante complementación estructural Download PDF

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Publication number
ES2926463T3
ES2926463T3 ES14769752T ES14769752T ES2926463T3 ES 2926463 T3 ES2926463 T3 ES 2926463T3 ES 14769752 T ES14769752 T ES 14769752T ES 14769752 T ES14769752 T ES 14769752T ES 2926463 T3 ES2926463 T3 ES 2926463T3
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ES
Spain
Prior art keywords
luminescence
peptide
luminescent
polypeptide
nlpoly
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Active
Application number
ES14769752T
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English (en)
Spanish (es)
Inventor
Andrew Dixon
Lance Encell
Mary Hall
Keith Wood
Monika Wood
Marie Schwinn
Brock Binkowski
Hicham Zegzouti
Nidhi Nath
Subhanjan Mondal
Said Goueli
Poncho Meisenheimer
Thomas Kirkland
James Unch
Dileep Pulukkunat
Matthew Robers
Melanie Dart
Thomas Machleidt
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Promega Corp
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Promega Corp
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/02—Marketing; Price estimation or determination; Fundraising
    • G06Q30/0283—Price estimation or determination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/06—Buying, selling or leasing transactions
    • G06Q30/0601—Electronic shopping [e-shopping]
    • G06Q30/0631—Recommending goods or services
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/02—Services making use of location information
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/30—Services specially adapted for particular environments, situations or purposes
    • H04W4/35—Services specially adapted for particular environments, situations or purposes for the management of goods or merchandise
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/30—Services specially adapted for particular environments, situations or purposes
    • H04W4/38—Services specially adapted for particular environments, situations or purposes for collecting sensor information
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Business, Economics & Management (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Finance (AREA)
  • Accounting & Taxation (AREA)
  • Development Economics (AREA)
  • General Engineering & Computer Science (AREA)
  • Strategic Management (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Theoretical Computer Science (AREA)
  • General Business, Economics & Management (AREA)
  • Marketing (AREA)
  • Economics (AREA)
  • Veterinary Medicine (AREA)
ES14769752T 2013-03-15 2014-03-13 Activación de la bioluminiscencia mediante complementación estructural Active ES2926463T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361791549P 2013-03-15 2013-03-15
PCT/US2014/026354 WO2014151736A1 (en) 2013-03-15 2014-03-13 Activation of bioluminescence by structural complementation

Publications (1)

Publication Number Publication Date
ES2926463T3 true ES2926463T3 (es) 2022-10-26

Family

ID=51581027

Family Applications (2)

Application Number Title Priority Date Filing Date
ES14769752T Active ES2926463T3 (es) 2013-03-15 2014-03-13 Activación de la bioluminiscencia mediante complementación estructural
ES20197758T Active ES2929362T3 (es) 2013-03-15 2014-03-13 Activación de la bioluminiscencia mediante complementación estructural

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES20197758T Active ES2929362T3 (es) 2013-03-15 2014-03-13 Activación de la bioluminiscencia mediante complementación estructural

Country Status (15)

Country Link
US (11) US9797889B2 (OSRAM)
EP (4) EP4169935A1 (OSRAM)
JP (4) JP6654557B2 (OSRAM)
KR (3) KR20230079494A (OSRAM)
CN (2) CN105143249A (OSRAM)
AU (3) AU2014236949C1 (OSRAM)
BR (1) BR112015023394B8 (OSRAM)
CA (1) CA2906063C (OSRAM)
DK (2) DK2970412T5 (OSRAM)
ES (2) ES2926463T3 (OSRAM)
IL (3) IL286816B (OSRAM)
PL (2) PL3783011T3 (OSRAM)
PT (2) PT3783011T (OSRAM)
SG (2) SG10201601929YA (OSRAM)
WO (1) WO2014151736A1 (OSRAM)

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BR112015023394B1 (pt) 2023-08-29
JP2023055734A (ja) 2023-04-18
AU2018256548B2 (en) 2020-05-14
JP7532562B2 (ja) 2024-08-13
PL3783011T3 (pl) 2022-11-21
US20160282340A1 (en) 2016-09-29
IL286816B (en) 2022-09-01
IL240985B (en) 2020-05-31
AU2020213288A1 (en) 2020-08-27
KR20210036422A (ko) 2021-04-02
KR20150129721A (ko) 2015-11-20
US20180196038A1 (en) 2018-07-12
SG11201507306VA (en) 2015-10-29
AU2018256548A1 (en) 2018-11-22
US20230342826A1 (en) 2023-10-26
US20180095074A1 (en) 2018-04-05
PT3783011T (pt) 2022-10-26
US20180306782A1 (en) 2018-10-25
EP3783011B1 (en) 2022-09-21
JP2020097597A (ja) 2020-06-25
US9797889B2 (en) 2017-10-24
US12367513B2 (en) 2025-07-22
PT2970412T (pt) 2022-09-13
IL273989B (en) 2021-10-31
EP2970412A4 (en) 2016-07-27
US11493504B2 (en) 2022-11-08
KR102675860B1 (ko) 2024-06-20
EP4177261A1 (en) 2023-05-10
US20180313825A1 (en) 2018-11-01
US9869670B2 (en) 2018-01-16
JP2024167207A (ja) 2024-12-03
BR112015023394B8 (pt) 2023-09-26
KR20230079494A (ko) 2023-06-07
US20250045806A1 (en) 2025-02-06
US10184936B2 (en) 2019-01-22
SG10201601929YA (en) 2016-04-28
AU2014236949B2 (en) 2018-08-02
DK2970412T3 (da) 2022-08-29
CN117024548A (zh) 2023-11-10
DK2970412T5 (da) 2024-10-14
IL286816A (en) 2021-10-31
US10288605B2 (en) 2019-05-14
US9797890B2 (en) 2017-10-24
WO2014151736A1 (en) 2014-09-25
JP6654557B2 (ja) 2020-02-26
AU2020213288B2 (en) 2022-07-07
BR112015023394A2 (pt) 2017-11-28
US20250022022A1 (en) 2025-01-16
CN105143249A (zh) 2015-12-09
IL273989A (en) 2020-05-31
PL2970412T3 (pl) 2022-11-14
US12366572B2 (en) 2025-07-22
CA2906063A1 (en) 2014-09-25
DK3783011T5 (da) 2024-08-19
CA2906063C (en) 2025-10-07
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US20200292534A1 (en) 2020-09-17
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