ES2916335T3 - Receptores de antígeno quimérico heterodimerizable basados en cereblon - Google Patents
Receptores de antígeno quimérico heterodimerizable basados en cereblon Download PDFInfo
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- ES2916335T3 ES2916335T3 ES17862754T ES17862754T ES2916335T3 ES 2916335 T3 ES2916335 T3 ES 2916335T3 ES 17862754 T ES17862754 T ES 17862754T ES 17862754 T ES17862754 T ES 17862754T ES 2916335 T3 ES2916335 T3 ES 2916335T3
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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| PCT/US2017/057474 WO2018075820A2 (en) | 2016-10-20 | 2017-10-19 | Cereblon-based heterodimerizable chimeric antigen receptors |
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| HRP20241553T1 (hr) | 2017-07-10 | 2025-01-17 | Celgene Corporation | 4-(4-(4-(((2-(2,6-dioksopiperidin-3-il)-l-oksoizoindolin-4-il)oksi)metil)benzil)piperazin-l-il)-3-fluorobenzonitril kao antiproliferativni spoj |
| IL321733A (en) * | 2017-10-18 | 2025-08-01 | Novartis Ag | Compositions and methods for selective degradation of proteins |
| PL3703750T3 (pl) | 2017-11-01 | 2025-04-07 | Juno Therapeutics, Inc. | Chimeryczne receptory antygenowe specyficzne dla antygenu dojrzewania komórek b i kodujące polinukleotydy |
| WO2019089982A1 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Method of assessing activity of recombinant antigen receptors |
| MA49911A (fr) | 2017-11-01 | 2020-06-24 | Juno Therapeutics Inc | Anticorps et récepteurs antigéniques chimériques spécifiques de l'antigene de maturation des lymphocytes b |
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| US20210292389A1 (en) * | 2018-08-10 | 2021-09-23 | Sangamo Therapeutics France | New car constructs comprising tnfr2 domains |
| CA3109747A1 (en) * | 2018-10-05 | 2020-04-09 | St. Anna Kinderkrebsforschung | A group of chimeric antigen receptors (cars) |
| US12263190B2 (en) * | 2018-11-08 | 2025-04-01 | Juno Therapeutics, Inc. | Methods and combinations for treatment and T cell modulation |
| WO2020116686A1 (ko) | 2018-12-06 | 2020-06-11 | 고려대학교 산학협력단 | 인간 항-antxr 키메라 항원 수용체 및 이의 용도 |
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| BR112022014020A2 (pt) * | 2020-01-20 | 2022-10-11 | Kangpu Biopharmaceuticals Ltd | Derivado de isoindolina e composição farmacêutica e uso do mesmo |
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| US20240374591A1 (en) * | 2021-06-25 | 2024-11-14 | Celgene Corporation | Cereblon binding compounds, compositions thereof, and methods of treatment therewith |
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| EP3528851A4 (en) | 2020-06-03 |
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