ES2904911T3 - Anticuerpos anti-receptor P2X7 y fragmentos de los mismos - Google Patents

Anticuerpos anti-receptor P2X7 y fragmentos de los mismos Download PDF

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Publication number
ES2904911T3
ES2904911T3 ES18175591T ES18175591T ES2904911T3 ES 2904911 T3 ES2904911 T3 ES 2904911T3 ES 18175591 T ES18175591 T ES 18175591T ES 18175591 T ES18175591 T ES 18175591T ES 2904911 T3 ES2904911 T3 ES 2904911T3
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ES
Spain
Prior art keywords
sequence
seq
antibody
binding site
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18175591T
Other languages
English (en)
Spanish (es)
Inventor
Julian Alexander Barden
Neil Brewis
Philip Jones
Steven Grant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosceptre Aust Pty Ltd
Biosceptre Pty Ltd
Original Assignee
Biosceptre Aust Pty Ltd
Biosceptre Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009903928A external-priority patent/AU2009903928A0/en
Application filed by Biosceptre Aust Pty Ltd, Biosceptre Pty Ltd filed Critical Biosceptre Aust Pty Ltd
Application granted granted Critical
Publication of ES2904911T3 publication Critical patent/ES2904911T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES18175591T 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos Active ES2904911T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU2009903928A AU2009903928A0 (en) 2009-08-20 Anti P2X7 receptor antibodies and fragments thereof

Publications (1)

Publication Number Publication Date
ES2904911T3 true ES2904911T3 (es) 2022-04-06

Family

ID=43606479

Family Applications (3)

Application Number Title Priority Date Filing Date
ES15178381T Active ES2704711T3 (es) 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
ES18175591T Active ES2904911T3 (es) 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
ES10809371.7T Active ES2557456T3 (es) 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES15178381T Active ES2704711T3 (es) 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES10809371.7T Active ES2557456T3 (es) 2009-08-20 2010-08-20 Anticuerpos anti-receptor P2X7 y fragmentos de los mismos

Country Status (5)

Country Link
US (6) US9127059B2 (https=)
EP (3) EP2467404B1 (https=)
JP (3) JP5936067B2 (https=)
ES (3) ES2704711T3 (https=)
WO (1) WO2011020155A1 (https=)

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CN110054691B (zh) * 2019-05-09 2021-09-07 潍坊医学院 一种抗人p2rx7单克隆抗体的杂交瘤细胞系
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CN111234016B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的全人源单克隆抗体及应用
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Also Published As

Publication number Publication date
ES2557456T3 (es) 2016-01-26
US20150266969A1 (en) 2015-09-24
EP3395832B1 (en) 2021-11-24
EP2966090B1 (en) 2018-10-10
US12129295B2 (en) 2024-10-29
US10053508B2 (en) 2018-08-21
US9127059B2 (en) 2015-09-08
EP2966090A1 (en) 2016-01-13
US20120282278A1 (en) 2012-11-08
EP3395832A1 (en) 2018-10-31
ES2704711T3 (es) 2019-03-19
EP2467404A1 (en) 2012-06-27
EP2467404A4 (en) 2013-01-23
US9688771B2 (en) 2017-06-27
JP6417016B2 (ja) 2018-10-31
JP2016136949A (ja) 2016-08-04
JP2018023396A (ja) 2018-02-15
US20170327576A1 (en) 2017-11-16
EP2467404B1 (en) 2015-09-30
JP2013502204A (ja) 2013-01-24
US20190040129A1 (en) 2019-02-07
JP5936067B2 (ja) 2016-06-15
HK1168365A1 (en) 2012-12-28
JP6224141B2 (ja) 2017-11-01
US10988532B2 (en) 2021-04-27
US20220315652A1 (en) 2022-10-06
US20250084161A1 (en) 2025-03-13
WO2011020155A1 (en) 2011-02-24

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