ES2892751T3 - Sistemas y métodos para el procesamiento de muestras en un recipiente cerrado y dispositivos relacionados - Google Patents
Sistemas y métodos para el procesamiento de muestras en un recipiente cerrado y dispositivos relacionados Download PDFInfo
- Publication number
- ES2892751T3 ES2892751T3 ES07835665T ES07835665T ES2892751T3 ES 2892751 T3 ES2892751 T3 ES 2892751T3 ES 07835665 T ES07835665 T ES 07835665T ES 07835665 T ES07835665 T ES 07835665T ES 2892751 T3 ES2892751 T3 ES 2892751T3
- Authority
- ES
- Spain
- Prior art keywords
- container
- barrier
- closed
- tray
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims description 116
- 238000012545 processing Methods 0.000 title claims description 108
- 230000004888 barrier function Effects 0.000 claims abstract description 139
- 239000012530 fluid Substances 0.000 claims abstract description 105
- 238000004891 communication Methods 0.000 claims abstract description 18
- 239000003153 chemical reaction reagent Substances 0.000 claims description 53
- 150000007523 nucleic acids Chemical class 0.000 claims description 51
- 108020004707 nucleic acids Proteins 0.000 claims description 49
- 102000039446 nucleic acids Human genes 0.000 claims description 49
- 230000008569 process Effects 0.000 claims description 42
- 238000010828 elution Methods 0.000 claims description 34
- 239000002699 waste material Substances 0.000 claims description 33
- 238000012546 transfer Methods 0.000 claims description 24
- 230000027455 binding Effects 0.000 claims description 21
- 238000007789 sealing Methods 0.000 claims description 19
- 238000001816 cooling Methods 0.000 claims description 12
- 238000011068 loading method Methods 0.000 claims description 9
- 230000008859 change Effects 0.000 claims description 6
- 238000003672 processing method Methods 0.000 claims description 2
- 230000003116 impacting effect Effects 0.000 claims 1
- 238000005086 pumping Methods 0.000 claims 1
- 230000003134 recirculating effect Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 description 96
- 239000000523 sample Substances 0.000 description 40
- 239000000463 material Substances 0.000 description 30
- 239000007788 liquid Substances 0.000 description 28
- 230000007246 mechanism Effects 0.000 description 27
- 238000005259 measurement Methods 0.000 description 23
- 238000003752 polymerase chain reaction Methods 0.000 description 21
- 230000003321 amplification Effects 0.000 description 19
- 230000033001 locomotion Effects 0.000 description 19
- 238000003199 nucleic acid amplification method Methods 0.000 description 19
- 238000004519 manufacturing process Methods 0.000 description 18
- 239000002609 medium Substances 0.000 description 15
- 238000003860 storage Methods 0.000 description 13
- 206010028980 Neoplasm Diseases 0.000 description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 12
- 238000006243 chemical reaction Methods 0.000 description 11
- 238000004590 computer program Methods 0.000 description 11
- 238000011109 contamination Methods 0.000 description 11
- 238000001459 lithography Methods 0.000 description 11
- 239000012472 biological sample Substances 0.000 description 10
- 239000012528 membrane Substances 0.000 description 10
- 108020004414 DNA Proteins 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 9
- 102000004169 proteins and genes Human genes 0.000 description 9
- 238000000746 purification Methods 0.000 description 9
- 238000004806 packaging method and process Methods 0.000 description 8
- 239000000758 substrate Substances 0.000 description 8
- 238000003556 assay Methods 0.000 description 7
- 238000000151 deposition Methods 0.000 description 7
- 239000003814 drug Substances 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 239000010410 layer Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000002299 complementary DNA Substances 0.000 description 6
- 230000008021 deposition Effects 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 239000000377 silicon dioxide Substances 0.000 description 6
- 238000013461 design Methods 0.000 description 5
- 230000002255 enzymatic effect Effects 0.000 description 5
- 238000005530 etching Methods 0.000 description 5
- 238000001704 evaporation Methods 0.000 description 5
- 230000008020 evaporation Effects 0.000 description 5
- 244000052769 pathogen Species 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 229960005486 vaccine Drugs 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- -1 cyclic nucleic acid Chemical class 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 238000009413 insulation Methods 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000013307 optical fiber Substances 0.000 description 4
- 238000000206 photolithography Methods 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 108091005461 Nucleic proteins Proteins 0.000 description 3
- 230000004570 RNA-binding Effects 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 3
- 238000012865 aseptic processing Methods 0.000 description 3
- 239000010836 blood and blood product Substances 0.000 description 3
- 229940125691 blood product Drugs 0.000 description 3
- 238000011018 current good manufacturing practice Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 229910052710 silicon Inorganic materials 0.000 description 3
- 239000010703 silicon Substances 0.000 description 3
- 238000004544 sputter deposition Methods 0.000 description 3
- 229920002725 thermoplastic elastomer Polymers 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 238000001015 X-ray lithography Methods 0.000 description 2
- 238000011481 absorbance measurement Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 229940037642 autologous vaccine Drugs 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 238000004113 cell culture Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000002508 contact lithography Methods 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 2
- 238000001312 dry etching Methods 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 239000000806 elastomer Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000007717 exclusion Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000013056 hazardous product Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000010884 ion-beam technique Methods 0.000 description 2
- 238000007834 ligase chain reaction Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000001393 microlithography Methods 0.000 description 2
- 239000004005 microsphere Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 238000000059 patterning Methods 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 229920002120 photoresistant polymer Polymers 0.000 description 2
- 238000001020 plasma etching Methods 0.000 description 2
- 230000037452 priming Effects 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 238000010839 reverse transcription Methods 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000007650 screen-printing Methods 0.000 description 2
- 239000000565 sealant Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000004528 spin coating Methods 0.000 description 2
- 238000000992 sputter etching Methods 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 238000013519 translation Methods 0.000 description 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- 108091093088 Amplicon Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000219198 Brassica Species 0.000 description 1
- 235000003351 Brassica cretica Nutrition 0.000 description 1
- 235000003343 Brassica rupestris Nutrition 0.000 description 1
- 230000004568 DNA-binding Effects 0.000 description 1
- 102000016911 Deoxyribonucleases Human genes 0.000 description 1
- 108010053770 Deoxyribonucleases Proteins 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 241000725303 Human immunodeficiency virus Species 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 238000002123 RNA extraction Methods 0.000 description 1
- 239000013614 RNA sample Substances 0.000 description 1
- 230000006819 RNA synthesis Effects 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000000137 annealing Methods 0.000 description 1
- 239000006117 anti-reflective coating Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000004500 asepsis Methods 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000003131 biological toxin Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 1
- 238000010804 cDNA synthesis Methods 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 230000003196 chaotropic effect Effects 0.000 description 1
- 238000003486 chemical etching Methods 0.000 description 1
- 238000005229 chemical vapour deposition Methods 0.000 description 1
- 239000012501 chromatography medium Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 238000013523 data management Methods 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 238000000708 deep reactive-ion etching Methods 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000000609 electron-beam lithography Methods 0.000 description 1
- 210000003527 eukaryotic cell Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001900 extreme ultraviolet lithography Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000004374 forensic analysis Methods 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000011194 good manufacturing practice Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000009169 immunotherapy Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000000025 interference lithography Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 238000005468 ion implantation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000011901 isothermal amplification Methods 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 238000001465 metallisation Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 238000001451 molecular beam epitaxy Methods 0.000 description 1
- 239000010813 municipal solid waste Substances 0.000 description 1
- 235000010460 mustard Nutrition 0.000 description 1
- 238000001821 nucleic acid purification Methods 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 238000002039 particle-beam lithography Methods 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000002294 plasma sputter deposition Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 238000003498 protein array Methods 0.000 description 1
- 238000001742 protein purification Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000012372 quality testing Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000000263 scanning probe lithography Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000002174 soft lithography Methods 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000005118 spray pyrolysis Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000026676 system process Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000005382 thermal cycling Methods 0.000 description 1
- 238000002207 thermal evaporation Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000005641 tunneling Effects 0.000 description 1
- 238000007514 turning Methods 0.000 description 1
- 238000007666 vacuum forming Methods 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 244000052613 viral pathogen Species 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
- B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L1/00—Measuring force or stress, in general
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L1/00—Enclosures; Chambers
- B01L1/02—Air-pressure chambers; Air-locks therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/142—Preventing evaporation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0378—Shapes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Robotics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Sustainable Development (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76008706P | 2006-01-18 | 2006-01-18 | |
| PCT/US2007/001170 WO2008018904A2 (en) | 2006-01-18 | 2007-01-17 | Systems and methods for processing samples in a closed container, and related devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2892751T3 true ES2892751T3 (es) | 2022-02-04 |
Family
ID=39033435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07835665T Active ES2892751T3 (es) | 2006-01-18 | 2007-01-17 | Sistemas y métodos para el procesamiento de muestras en un recipiente cerrado y dispositivos relacionados |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8030080B2 (enExample) |
| EP (1) | EP1976670B1 (enExample) |
| JP (1) | JP5254040B2 (enExample) |
| KR (1) | KR101321658B1 (enExample) |
| CN (2) | CN101370622B (enExample) |
| AU (1) | AU2007282135C1 (enExample) |
| CA (1) | CA2635268C (enExample) |
| ES (1) | ES2892751T3 (enExample) |
| WO (1) | WO2008018904A2 (enExample) |
Families Citing this family (167)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0517910D0 (en) * | 2005-09-05 | 2005-10-12 | Enigma Diagnostics Ltd | Liquid transfer device |
| DK2021807T3 (da) * | 2006-04-24 | 2013-09-23 | Protedyne Corp | Robotsystem med autonomt betjenelige værktøjer |
| GB0717461D0 (en) * | 2007-09-07 | 2007-10-17 | Mole Genetics As | Separation apparatus |
| BR122020017678B1 (pt) | 2007-10-02 | 2021-08-03 | Labrador Diagnostics Llc | Sistema para detecção automática de um analito em uma amostra de fluido corporal |
| US10300482B2 (en) * | 2010-12-09 | 2019-05-28 | Akonni Biosystems, Inc. | Sample analysis system |
| US10125388B2 (en) | 2007-10-31 | 2018-11-13 | Akonni Biosystems, Inc. | Integrated sample processing system |
| EP3656284A1 (en) | 2008-04-16 | 2020-05-27 | United States Endoscopy Group, Inc. | Adaptor for a water bottle of an endoscope |
| CA2639837C (en) * | 2008-09-29 | 2015-12-01 | Peter Lea | Method and device to remove fluid and vapor |
| WO2010040473A2 (de) * | 2008-10-06 | 2010-04-15 | Ulrich Mohr | Kultur-/expositionsvorrichtung, insbesondere für zell- und/oder bakterienkulturen |
| JP5384903B2 (ja) * | 2008-10-14 | 2014-01-08 | ユニバーサル・バイオ・リサーチ株式会社 | 温度制御反応処理装置および温度制御反応処理方法 |
| US9103782B2 (en) | 2008-12-02 | 2015-08-11 | Malvern Instruments Incorporated | Automatic isothermal titration microcalorimeter apparatus and method of use |
| JP2010194685A (ja) * | 2009-02-26 | 2010-09-09 | Tokyo Electron Ltd | 作業台 |
| JP5872765B2 (ja) * | 2009-12-10 | 2016-03-01 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 空間的分離による増幅システム |
| JP5623888B2 (ja) | 2009-12-10 | 2014-11-12 | エフ.ホフマン−ラ ロシュアーゲーF.Hoffmann−La Roche Aktiengesellschaft | 分析対象物を分離して検出する方法 |
| JP4919119B2 (ja) * | 2010-01-19 | 2012-04-18 | 株式会社日立プラントテクノロジー | 試薬分注ノズルによる分取・分注方法および試薬分取・分注機構 |
| US9242244B2 (en) * | 2010-02-09 | 2016-01-26 | Douglas T. Gjerde | Method and apparatus for pipette tip columns |
| US9102979B2 (en) * | 2010-02-23 | 2015-08-11 | Rheonix, Inc. | Self-contained biological assay apparatus, methods, and applications |
| JP6058399B2 (ja) * | 2010-02-23 | 2017-01-11 | レオニックス,インコーポレイテッド | 自己完結的生物学的アッセイ装置、方法及び応用 |
| WO2011116230A2 (en) | 2010-03-18 | 2011-09-22 | Biotix, Inc. | Pipette tip trays |
| FR2958401A1 (fr) * | 2010-04-01 | 2011-10-07 | Braun Medical Sas | Dispositif de prelevement d'un echantillon de liquide d'une poche souple |
| KR101368463B1 (ko) * | 2010-04-23 | 2014-03-03 | 나노바이오시스 주식회사 | 2개의 열 블록을 포함하는 pcr 장치 |
| US9144373B2 (en) | 2010-04-26 | 2015-09-29 | United States Endoscopy Group, Inc. | Water bottle adapter for coupling an endoscope to a water bottle |
| US20120277536A1 (en) * | 2010-04-26 | 2012-11-01 | Kaye Christopher J | Water bottle adapter for coupling an endoscope to a water bottle |
| CN104345165B (zh) * | 2010-07-23 | 2016-09-14 | 贝克曼考尔特公司 | 包含分析单元的系统和方法 |
| WO2012028737A1 (en) * | 2010-09-02 | 2012-03-08 | Qiagen Gmbh | Method for isolating a target nucleic acid including small target nucleic acids with high yield |
| USD674112S1 (en) | 2010-10-22 | 2013-01-08 | T2 Biosystems, Inc. | Modular cartridge assembly |
| USD673293S1 (en) * | 2010-10-22 | 2012-12-25 | T2 Biosystems, Inc. | Modular cartridge assembly |
| EP3239296A1 (en) | 2010-11-30 | 2017-11-01 | Life Technologies Corporation | Alkylene glycols and polymers and copolymers thereof for direct isolation of nucleic acid from embedded samples |
| JP5714316B2 (ja) * | 2010-12-22 | 2015-05-07 | 株式会社日立製作所 | 細胞培養装置 |
| MX2013008339A (es) | 2011-01-21 | 2014-02-11 | Theranos Inc | Sistemas y metodos para maximizacion de uso de muestras. |
| WO2012105176A1 (ja) * | 2011-01-31 | 2012-08-09 | 株式会社 日立ハイテクノロジーズ | 核酸検査装置 |
| US10684303B2 (en) * | 2011-07-22 | 2020-06-16 | Vanrx Pharmasystems Inc. | Method for protecting and unprotecting the fluid path in a controlled environment enclosure |
| ES2869383T3 (es) | 2011-07-22 | 2021-10-25 | Vanrx Pharmaceuticals Inc | Método para proteger y desproteger la trayectoria de fluido en un recinto de entorno controlado |
| ES2797448T3 (es) | 2011-08-01 | 2020-12-02 | Bio Rad Laboratories | Sistema de captura de células |
| US10466160B2 (en) | 2011-08-01 | 2019-11-05 | Celsee Diagnostics, Inc. | System and method for retrieving and analyzing particles |
| US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
| US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
| US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
| US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US8932543B2 (en) * | 2011-09-21 | 2015-01-13 | Sakura Finetek U.S.A., Inc. | Automated staining system and reaction chamber |
| US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
| US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
| US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
| USD753311S1 (en) | 2011-10-12 | 2016-04-05 | Alere Switzerland Gmbh | Isothermal nucleic acid amplification meter |
| JP2013134069A (ja) * | 2011-12-26 | 2013-07-08 | Hitachi High-Technologies Corp | 自動分析装置 |
| EP2812163B9 (en) * | 2012-02-08 | 2025-06-18 | Vanrx Pharmasystems Inc. | Articulated arm apparatus and system |
| FR2987896B1 (fr) * | 2012-03-08 | 2014-04-25 | Noviloire | Automate d'analyse medicale et procede correspondant |
| EP2830477A1 (en) | 2012-03-30 | 2015-02-04 | Bracco Diagnostics Inc. | Water bottle cap assemblies for an endoscopic device |
| WO2013158281A1 (en) | 2012-04-20 | 2013-10-24 | T2 Biosystems, Inc. | Compositions and methods for detection of candida species |
| JP6197030B2 (ja) * | 2012-04-27 | 2017-09-13 | セフェィド | 異種の処理モジュールを有する装置 |
| JP2013255447A (ja) * | 2012-06-12 | 2013-12-26 | Nippon Koden Corp | 細胞単離装置 |
| MX2012010985A (es) * | 2012-09-24 | 2014-03-24 | Diana Elizabeth Calva Mendez | Procedimiento y sistemas con contenedor que se acopla al dispositivo de pipeteo. |
| DK2900802T3 (da) | 2012-09-25 | 2025-09-15 | Bl Technologies Inc | Engangsbeholder til biobelastningsprøveindsamling og -detektion |
| DE102013200193A1 (de) | 2013-01-09 | 2014-07-10 | Hamilton Bonaduz Ag | Probenverarbeitungssystem mit Dosiervorrichtung und Thermocycler |
| US10737273B2 (en) | 2013-02-21 | 2020-08-11 | Biotix, Inc. | Pipette tip rack |
| US9108201B2 (en) | 2013-02-21 | 2015-08-18 | Biotix, Inc. | Pipette tip rack |
| USD724236S1 (en) * | 2013-02-21 | 2015-03-10 | Biotix, Inc. | Pipette tip rack assembly |
| GB201304797D0 (en) * | 2013-03-15 | 2013-05-01 | Diagnostics For The Real World Ltd | Apparatus and method for automated sample preparation and adaptor for use in the apparatus |
| US10391490B2 (en) | 2013-05-31 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
| US9536699B2 (en) | 2013-07-08 | 2017-01-03 | Carl Zeiss Microscopy, Llc | Charged particle beam system and method of operating a charged particle beam system |
| EP3039619B1 (en) * | 2013-08-26 | 2021-09-22 | Equashield Medical Ltd. | Method and apparatus for monitoring, documenting and assisting with the manual compounding of medications |
| CN106119101B (zh) * | 2013-10-15 | 2018-07-13 | 周国华 | 集核酸提取、扩增与检测一体化的装置 |
| MX376649B (es) * | 2013-11-13 | 2025-03-07 | Stempeutics Res Private Limited | Sistema y método para procesamiento de muestras de tejido biológico. |
| IN2013CH05149A (enExample) * | 2013-11-13 | 2015-08-28 | Stempeutics Res Private Ltd | |
| KR20150101308A (ko) * | 2014-02-26 | 2015-09-03 | 삼성전자주식회사 | 미세유동장치 및 이를 포함하는 미세유동시스템 |
| US9827567B2 (en) * | 2014-04-22 | 2017-11-28 | Nanosphere, Inc. | Diagnostic cartridges having flexible seals |
| WO2015190010A1 (ja) * | 2014-06-09 | 2015-12-17 | 国立研究開発法人産業技術総合研究所 | プロトコルチャート作成装置、プロトコルチャート作成方法、コンピュータプログラム及びプロトコルチャート |
| DE102014108689A1 (de) * | 2014-06-20 | 2015-12-24 | Hamilton Bonaduz Ag | Pipettiervorrichtung mit Gehäuse |
| US9638608B2 (en) * | 2014-06-30 | 2017-05-02 | Beacon Technologies, LLC | Pipette tip system, device and method of use |
| US10661268B2 (en) | 2014-06-30 | 2020-05-26 | Beacon Technologies, LLC | Pipette tip system, device and method of use |
| EP3175247B1 (en) * | 2014-07-28 | 2020-08-19 | Douglas Scientific, LLC | Instrument for analyzing biological samples and reagents |
| JP6402853B2 (ja) * | 2014-07-29 | 2018-10-10 | 澁谷工業株式会社 | 遠心機 |
| KR101511217B1 (ko) * | 2014-10-01 | 2015-04-13 | 에이티아이 주식회사 | 지방세포 자동 처리 시스템 |
| WO2016086071A1 (en) * | 2014-11-24 | 2016-06-02 | Nueou, Inc. | Spectrally encoded consumable spectrometer apparatus and methods |
| US11478789B2 (en) | 2014-11-26 | 2022-10-25 | Medica Corporation | Automated microscopic cell analysis |
| US10625259B1 (en) | 2014-11-26 | 2020-04-21 | Medica Corporation | Automated microscopic cell analysis |
| US20170328924A1 (en) | 2014-11-26 | 2017-11-16 | Ronald Jones | Automated microscopic cell analysis |
| AU2016222728B2 (en) | 2015-02-27 | 2018-09-27 | Hycor Biomedical, Llc | Apparatuses and methods for suspending and washing the contents of a plurality of cuvettes |
| CN104807972A (zh) * | 2015-04-29 | 2015-07-29 | 钱震雯 | 药物成分检测装置 |
| CN104865395A (zh) * | 2015-05-21 | 2015-08-26 | 上海儒克生物科技有限公司 | 生物应用机器人、机器人执行模块及执行方法 |
| US20160349175A1 (en) * | 2015-05-28 | 2016-12-01 | Microaeth Corporation | Apparatus for receiving an analyte, method for characterizing an analyte, and substrate cartridge |
| KR101703600B1 (ko) | 2015-05-29 | 2017-02-07 | 현대자동차 주식회사 | 프라이머 시스템 및 이를 적용한 도포 장치 |
| WO2016201193A1 (en) * | 2015-06-11 | 2016-12-15 | MeasureMeNow, Inc. | Self-operating and transportable remote lab system |
| JP6555053B2 (ja) * | 2015-09-25 | 2019-08-07 | 株式会社安川電機 | ロボット制御方法及びロボットシステム |
| EP3892712B1 (en) * | 2015-12-01 | 2023-11-22 | Go!Foton, Inc. | Pcr reaction vessel, pcr device, and pcr method |
| CA3007930A1 (en) | 2015-12-10 | 2017-06-15 | Vanrx Pharmasystems Inc. | Apparatus and method for protecting and unprotecting a fluid path in a controlled environment enclosure |
| CA3011901A1 (en) | 2016-01-21 | 2017-07-27 | T2 Biosystems, Inc. | Nmr methods and systems for the rapid detection of bacteria |
| EP3862755B1 (en) | 2016-02-17 | 2025-01-15 | Becton, Dickinson and Company | Container shuttle transport assembly |
| WO2017156641A1 (en) * | 2016-03-18 | 2017-09-21 | Tci Manufacturing Inc. | System and method for manufacturing a flexible intermediate bulk container |
| ES2972583T3 (es) | 2016-04-22 | 2024-06-13 | Becton Dickinson Co | Analizador de diagnóstico automatizado y método para su funcionamiento |
| CN115754323A (zh) | 2016-04-22 | 2023-03-07 | 贝克顿·迪金森公司 | 自动化诊断分析仪和用于自动化诊断分析仪的操作的方法 |
| JP6880439B2 (ja) | 2016-06-03 | 2021-06-02 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 凝縮粒子計数器内の凝縮物を分離するためのシステム及び方法 |
| WO2017221155A1 (en) * | 2016-06-20 | 2017-12-28 | Genesis Technologies Limited | Automated cell processing systems and methods |
| EP3474994A4 (en) * | 2016-06-24 | 2019-06-05 | Kobra Biosolutions, LLC | VERIFYING PIPETTE AND VISIBILITY DEVICE |
| JP6810552B2 (ja) * | 2016-08-12 | 2021-01-06 | 川崎重工業株式会社 | アイソレータシステム |
| CN109642910B (zh) * | 2016-09-08 | 2022-04-29 | 株式会社日立高新技术 | 自动分析装置 |
| EP3747544A1 (en) * | 2016-10-07 | 2020-12-09 | Boehringer Ingelheim Vetmedica GmbH | Method and analysis system for testing a sample |
| EP3335844B1 (de) * | 2016-12-15 | 2019-10-30 | Pharma Integration S.R.L. | Konstruktiver aufbau eines containments, bestimmt zur automatisierten produktion pharmazeutischer oder biotechnischer artikel |
| US10471425B2 (en) * | 2017-02-16 | 2019-11-12 | International Business Machines Corporation | Automated machine for sorting of biological fluids |
| US12392692B2 (en) | 2017-03-09 | 2025-08-19 | Hologic, Inc. | Systems for automated preparation of biological specimens |
| TWI755498B (zh) * | 2017-03-09 | 2022-02-21 | 美商好樂杰公司 | 自動化製備生物樣本之系統及方法 |
| WO2018208563A1 (en) | 2017-05-09 | 2018-11-15 | Siemens Healthcare Diagnostics Inc. | Methods and apparatus for rapid heating of biological specimens |
| US11227300B2 (en) * | 2017-06-09 | 2022-01-18 | Modfind Llc | Computer-network-based referral service functions and user interfaces |
| WO2019014306A2 (en) * | 2017-07-13 | 2019-01-17 | Argos Therapeutics, Inc. | SYSTEMS, APPARATUS, METHODS AND ASSOCIATED DEVICES FOR AUTOMATED PROCESSING |
| WO2019046307A1 (en) | 2017-08-29 | 2019-03-07 | Celsee Diagnostics, Inc. | SYSTEM AND METHOD FOR ISOLATING AND ANALYZING CELLS |
| DE102017216366A1 (de) * | 2017-09-14 | 2019-03-14 | Vetter Pharma-Fertigung GmbH & Co. KG | Transportabler Reinraum, Verfahren zur Herstellung eines transportablen Reinraums und Verfahren zur Befüllung eines Medikamentenbehälters in einem transportablen Reinraum |
| US11047845B1 (en) | 2017-11-15 | 2021-06-29 | Medica Corporation | Control material and methods for cell analyzers |
| US10991264B2 (en) | 2017-11-23 | 2021-04-27 | Omnicell, Inc. | Multi-camera imaging for IV compounding |
| US10596319B2 (en) * | 2017-11-23 | 2020-03-24 | Aesynt Incorporated | Compounding device system |
| US11335444B2 (en) | 2017-11-30 | 2022-05-17 | Omnicell, Inc. | IV compounding systems and methods |
| EP4219014A1 (en) | 2018-01-23 | 2023-08-02 | F. Hoffmann-La Roche AG | Tube tray for secondary tubes and secondary tube handling module |
| SG10201801098PA (en) * | 2018-02-08 | 2019-09-27 | Delta Electronics Int’L Singapore Pte Ltd | Fluorescence Detection Instrument |
| US20210041473A1 (en) * | 2018-03-30 | 2021-02-11 | Porex Corporation | Robotic Liquid Handling System with On-Site, On-Demand Porous Filter Functional Media Assembly Capability for Disposable Liquid Handling Devices |
| EP3775932A4 (en) | 2018-04-07 | 2021-12-29 | Lumacyte LLC | Fluidic autosampler and incubator |
| CN108544531B (zh) * | 2018-04-12 | 2020-11-10 | 江苏科技大学 | 一种基于视觉标定的自动化验机械臂装置、控制系统及其控制方法 |
| JP6925298B2 (ja) * | 2018-04-24 | 2021-08-25 | 株式会社日立産機システム | 安全キャビネット |
| CN112423883A (zh) | 2018-07-12 | 2021-02-26 | 卢米耐克斯公司 | 用于进行可变样品制备和分析过程的系统和方法 |
| CN109084859B (zh) * | 2018-08-23 | 2020-05-29 | 上海真兰仪表科技股份有限公司 | 一种用于小型化高精度膜式燃气表的纳米添加剂皮膜 |
| CN108896594B (zh) * | 2018-09-18 | 2024-02-06 | 中国工程物理研究院流体物理研究所 | 一种材料二次电子发射特性测量样品预处理装置 |
| US10775395B2 (en) * | 2018-10-18 | 2020-09-15 | Arctoris Limited | System and method of performing a biological experiment with adaptive cybernetic control of procedural conditions |
| US20210308880A1 (en) * | 2018-11-07 | 2021-10-07 | Abb Schweiz Ag | Self-Disinfecting Robot and Method For Disinfecting A Robot |
| WO2020102032A1 (en) * | 2018-11-16 | 2020-05-22 | Particle Measuring Systems, Inc. | Particle sampling systems and methods for robotic controlled manufacturing barrier systems |
| CN119951603A (zh) | 2019-01-30 | 2025-05-09 | 生命技术控股私人有限公司 | 生物分析系统和方法 |
| CN111803997B (zh) * | 2019-04-10 | 2023-11-17 | 中国水产科学研究院 | 全自动震荡提取净化装置及前处理方法 |
| US10633693B1 (en) | 2019-04-16 | 2020-04-28 | Celsee Diagnostics, Inc. | System and method for leakage control in a particle capture system |
| SG11202112151UA (en) | 2019-05-07 | 2021-12-30 | Bio Rad Laboratories | System and method for automated single cell processing |
| US11273439B2 (en) | 2019-05-07 | 2022-03-15 | Bio-Rad Laboratories, Inc. | System and method for target material retrieval from microwells |
| JP2022539739A (ja) * | 2019-06-26 | 2022-09-13 | バイオ-ラッド ラボラトリーズ インコーポレイテッド | マイクロウェルからの標的物質の回収システムおよび方法 |
| IL268368B2 (en) * | 2019-07-30 | 2023-11-01 | Equashield Medical Ltd | Ingredients for open systems of liquid drug delivery and a robotic system that utilizes them |
| EP4045646A4 (en) * | 2019-10-18 | 2023-11-22 | Encodia, Inc. | AUTOMATED TREATMENT OF MACROMOLECULES FOR ANALYSIS AND ASSOCIATED APPARATUS |
| US11654437B2 (en) * | 2019-10-23 | 2023-05-23 | Quandx Inc. | Assay cartridg for molecular diagnosis |
| TWI801797B (zh) | 2020-01-21 | 2023-05-11 | 美商粒子監測系統有限公司 | 撞擊器及用於對來自一流體流之生物顆粒取樣之方法 |
| CN115715232A (zh) * | 2020-05-08 | 2023-02-24 | 生命技术控股私人有限公司 | 生物分析系统和方法 |
| CN111534423A (zh) * | 2020-05-12 | 2020-08-14 | 西安交通大学 | 一种群体核酸测试混合装置及方法 |
| EP3926031A1 (en) * | 2020-06-15 | 2021-12-22 | ESTR Biosystems GmbH | Assembly system for a smart tank for a bio-pharma process |
| EP3939896A1 (de) * | 2020-07-17 | 2022-01-19 | Pharma Integration S.R.L. | Funktionsmodul zum heranführen an eine in einem prozessraum eines containments positionierte dosierstation und verfahren dazu |
| EP4121557A4 (en) | 2020-08-06 | 2024-05-01 | Singular Genomics Systems, Inc. | Spatial sequencing |
| US11492662B2 (en) | 2020-08-06 | 2022-11-08 | Singular Genomics Systems, Inc. | Methods for in situ transcriptomics and proteomics |
| CA3190411A1 (en) * | 2020-08-31 | 2022-03-03 | Curium Us Llc | Container closure including vortex-generating feature |
| CN112089447A (zh) * | 2020-10-21 | 2020-12-18 | 高进贤 | 一种高效自动化新冠病毒核酸智能采集系统 |
| KR102404424B1 (ko) * | 2020-12-10 | 2022-06-02 | 에이치비솔루션(주) | 샘플 홀더 및 원터치 트랜스퍼 장치 |
| CN112844206B (zh) * | 2021-01-22 | 2022-10-25 | 顾桂敏 | 一种微生物检测中自动配制试剂的智能装置 |
| WO2022163962A1 (ko) * | 2021-01-29 | 2022-08-04 | 주식회사 싱크오르비스 | 생명과학 및 화학 실험을 수행하는 실험 자동화 장치 및 그 방법 |
| WO2022235764A1 (en) | 2021-05-05 | 2022-11-10 | Singular Genomics Systems, Inc. | Multiomic analysis device and methods of use thereof |
| CN113192813A (zh) * | 2021-05-27 | 2021-07-30 | 南京珀斯佩特电子科技有限公司 | 一种利用机械臂的等离子装置 |
| IT202100014453A1 (it) * | 2021-06-03 | 2022-12-03 | Rawica S R L | Macchina di trattamento di oggetti |
| GB2605850B (en) * | 2021-07-06 | 2023-04-26 | Cellularorigins Ltd | Bioprocessing system |
| CN113607522B (zh) * | 2021-08-04 | 2023-12-01 | 深圳市美雅洁技术股份有限公司 | 一种连续多缸快速病理处理装置 |
| CN113624985B (zh) * | 2021-08-16 | 2023-06-30 | 优爱宝智能机器人(浙江)有限公司 | 基于多关节或scara机器人的高通量加样处理装置 |
| EP4430381A4 (en) * | 2021-11-11 | 2025-09-17 | Black Light Surgical Inc | TISSUE CHARACTERIZATION SYSTEMS AND METHODS |
| WO2023107539A1 (en) | 2021-12-10 | 2023-06-15 | Bio-Rad Laboratories, Inc. | Compositions, methods, and systems for sample processing with morphology-adjustable functionalized particles |
| CN114225997B (zh) * | 2021-12-31 | 2022-11-22 | 深圳市华晨阳科技有限公司 | 一种用于基因检测的检测装置 |
| DE102022100678A1 (de) * | 2022-01-12 | 2023-07-13 | Tt Innovation Ag | Transfervorrichtung, Verfahren und Verwendung einer Transfervorrichtung zum Überführen wenigstens eines Funktionselements in eine Prozesskammer |
| CN114459859B (zh) * | 2022-02-16 | 2022-09-09 | 北京卢米斯生物科技有限公司 | 基于荧光素酶报告基因法的高通量二噁英自动检测装置 |
| WO2023170680A1 (en) | 2022-03-08 | 2023-09-14 | Equashield Medical Ltd | Fluid transfer station in a robotic pharmaceutical preparation system |
| KR102817938B1 (ko) * | 2022-09-21 | 2025-06-10 | 한국에너지기술연구원 | 촉매 성능 평가 자동화 시스템 |
| KR102793508B1 (ko) * | 2022-09-23 | 2025-04-09 | 주식회사 에스에프이 | 자동 검체 분주 시스템 |
| KR102809414B1 (ko) * | 2022-09-23 | 2025-05-19 | 한국화학연구원 | 무게법 기반의 시료 희석 및 분주 장치 |
| US20240218310A1 (en) * | 2022-12-28 | 2024-07-04 | Industrial Technology Research Institute | Cell culture device |
| WO2024249961A1 (en) | 2023-06-01 | 2024-12-05 | Singular Genomics Systems, Inc. | Methods and probes for detecting polynucleotide sequences in cells and tissues |
| DE102023130775A1 (de) * | 2023-11-07 | 2025-05-08 | KyooBe Tech GmbH | System und Verfahren zum Rüsten und/oder zum Aufbereiten von Prozesseinheiten zur Herstellung eines Produkts |
| WO2025151471A1 (en) * | 2024-01-09 | 2025-07-17 | Becton, Dickinson And Company | Apparatus, system, and method for controlled substance wasting |
| US20250298043A1 (en) * | 2024-03-22 | 2025-09-25 | Mayo Foundation For Medical Education And Research | Systems and methods for automated grossing of tissue samples |
| CN119869629B (zh) * | 2025-01-24 | 2025-11-11 | 重庆理工大学 | 一种具有隔离与净化功能的便携式实验安全教学装置 |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4876187A (en) | 1985-12-05 | 1989-10-24 | Meiogenics, Inc. | Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences |
| US4815256A (en) * | 1987-07-02 | 1989-03-28 | Bhmw Partnership | Capped container dispenser |
| JP2774121B2 (ja) * | 1987-07-31 | 1998-07-09 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 標的ポリヌクレオチド配列の選択的増幅 |
| US5030557A (en) | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
| CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| JP2650159B2 (ja) * | 1988-02-24 | 1997-09-03 | アクゾ・ノベル・エヌ・ベー | 核酸増幅方法 |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US4895280A (en) * | 1988-07-27 | 1990-01-23 | Microcare Chemical Corporation | Pressurized fluid remote dispenser including improved locking means |
| CA2020958C (en) * | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| EP0419180B1 (en) * | 1989-09-18 | 1994-08-03 | Canon Kabushiki Kaisha | Ink jet recording head and ink jet apparatus having same |
| DE4202561A1 (de) * | 1992-01-30 | 1993-08-05 | Boehringer Mannheim Gmbh | Vorrichtung zum dosierten zufuehren einer analysefluessigkeit |
| WO1993019827A1 (en) * | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
| KR100249110B1 (ko) * | 1992-05-06 | 2000-04-01 | 다니엘 엘. 캐시앙 | 핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트 |
| US5287857A (en) * | 1992-06-22 | 1994-02-22 | David Mann | Apparatus and method for obtaining an arterial biopsy |
| US5263299A (en) * | 1992-08-27 | 1993-11-23 | Imperial Packaging, Inc. | Apparatus for manually forming containers into portable packs |
| US5474303A (en) * | 1993-04-15 | 1995-12-12 | Coles; Carl R. | Actuator rod hermetic sealing apparatus employing concentric bellows and pressure compensating sealing liquid with liquid monitoring system |
| US5482205A (en) * | 1994-08-01 | 1996-01-09 | Sonoco Products Company | Spirally-wound easy-open container having a score cut opening panel |
| US5578270A (en) * | 1995-03-24 | 1996-11-26 | Becton Dickinson And Company | System for nucleic acid based diagnostic assay |
| US5883292A (en) * | 1996-01-17 | 1999-03-16 | Twenty-First Century Research Corporation | Reaction control by regulating internal condensation inside a reactor |
| JP2000500331A (ja) * | 1995-11-03 | 2000-01-18 | サーノフ コーポレイション | アッセイシステムおよびアッセイを実施する方法 |
| DE19610354C1 (de) * | 1996-03-15 | 1997-11-20 | Innova Gmbh | Vorrichtung, Verfahren und Einrichtung zur Isolierung von Nukleinsäuren |
| US5713138A (en) * | 1996-08-23 | 1998-02-03 | Research, Incorporated | Coating dryer system |
| US5795784A (en) * | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| US6518067B1 (en) * | 1997-02-17 | 2003-02-11 | Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf) | Automated chemical synthesis apparatus |
| JPH10323993A (ja) * | 1997-02-19 | 1998-12-08 | Canon Inc | 検出システム、該検出システムを用いる液体吐出記録装置と液体収納容器、及び、光量変化受光システム |
| US5934312A (en) * | 1997-04-10 | 1999-08-10 | Spillguard Development Llc | Drop chute spill guard |
| US5947890A (en) * | 1997-09-19 | 1999-09-07 | Spencer; Robert H. | Apparatus and improved method for safely dispensing and delivering liquid radiation for intraluminal radiation therapy |
| US5851492A (en) * | 1997-09-30 | 1998-12-22 | Blattner; Frederick R. | Microtiter plate sealing system |
| US6030582A (en) * | 1998-03-06 | 2000-02-29 | Levy; Abner | Self-resealing, puncturable container cap |
| EP2295144A3 (en) * | 1998-05-01 | 2011-07-27 | Gen-Probe Incorporated | System and method for incubating the contents of a reaction receptacle |
| US20020086431A1 (en) * | 2000-08-21 | 2002-07-04 | Markham Walter Bruce | Sample preparation and slide plating apparatus and method |
| US7220590B2 (en) * | 2001-03-14 | 2007-05-22 | Beckman Coulter, Inc. | Conductive plastic rack for pipette tips |
| DE10162780C1 (de) | 2001-04-25 | 2002-11-21 | Schlick Roto Jet Maschb Gmbh | Arbeitskammersystem |
| RU2206575C2 (ru) * | 2001-07-25 | 2003-06-20 | Институт молекулярной биологии им. В.А. Энгельгардта РАН | Композиция для иммобилизации биологических макромолекул в гидрогелях, способ приготовления композиции, биочип, способ проведения пцр на биочипе |
| JP2003057255A (ja) * | 2001-08-08 | 2003-02-26 | Aloka Co Ltd | 被処理物の処理装置 |
| US6579724B2 (en) * | 2001-09-13 | 2003-06-17 | First Ten Angstroms | Dispensing method and apparatus for dispensing very small quantities of fluid |
| WO2003036298A2 (en) | 2001-10-25 | 2003-05-01 | Exiqon A/S | Closed substrate platforms suitable for analysis of biomolecules |
| BRPI0310060B8 (pt) * | 2002-05-17 | 2021-07-27 | Becton Dickinson Co | sistema automatizado para isolar, amplificar e detectar uma seqüência de ácido nucléico alvo ou uma proteína |
| AU2003240959A1 (en) | 2002-05-28 | 2003-12-12 | Autogenomics, Inc. | Microarray detector and methods |
| US20060127365A1 (en) * | 2002-05-31 | 2006-06-15 | Victor Nurcombe | Method of cell therapy using fused cell hybrids |
| US20030226796A1 (en) * | 2002-06-11 | 2003-12-11 | 3M Innovative Properties Company | Modular system for separating components of a liquid sample |
| JP3865134B2 (ja) * | 2003-01-09 | 2007-01-10 | 横河電機株式会社 | バイオチップ用カートリッジ |
| ITMO20030178A1 (it) * | 2003-06-19 | 2004-12-20 | Sarong Spa | Apparato per la termoformatura di contenitori |
| EP1508809B1 (en) * | 2003-08-20 | 2007-02-28 | Sysmex Corporation | Sample analyzer and nucleic acid detector |
| CN1204945C (zh) * | 2003-09-05 | 2005-06-08 | 刘兆彦 | 一种管、筒或塔内构件立交盘 |
| EP1716249A2 (en) * | 2003-12-31 | 2006-11-02 | Applera Corporation, Applied Biosystems Group | Quantitative amplification and detection of small numbers of target polynucleotides |
| US20050266411A1 (en) * | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
| WO2006099507A2 (en) | 2005-03-11 | 2006-09-21 | Medical Instill Technologies, Inc. | Sterile de-molding apparatus and method |
-
2007
- 2007-01-17 AU AU2007282135A patent/AU2007282135C1/en not_active Ceased
- 2007-01-17 CN CN2007800024979A patent/CN101370622B/zh not_active Expired - Fee Related
- 2007-01-17 EP EP07835665.6A patent/EP1976670B1/en not_active Not-in-force
- 2007-01-17 US US12/159,748 patent/US8030080B2/en active Active
- 2007-01-17 WO PCT/US2007/001170 patent/WO2008018904A2/en not_active Ceased
- 2007-01-17 KR KR1020087017409A patent/KR101321658B1/ko not_active Expired - Fee Related
- 2007-01-17 ES ES07835665T patent/ES2892751T3/es active Active
- 2007-01-17 JP JP2008551336A patent/JP5254040B2/ja not_active Expired - Fee Related
- 2007-01-17 CA CA2635268A patent/CA2635268C/en active Active
- 2007-01-17 CN CN201310274447.3A patent/CN103499466B/zh not_active Expired - Fee Related
-
2011
- 2011-09-19 US US13/235,922 patent/US8211701B2/en not_active Expired - Fee Related
-
2012
- 2012-06-07 US US13/490,863 patent/US8431404B2/en not_active Expired - Fee Related
-
2013
- 2013-03-18 US US13/845,725 patent/US9040303B2/en active Active
-
2015
- 2015-04-21 US US14/692,131 patent/US9409178B2/en not_active Expired - Fee Related
-
2016
- 2016-07-21 US US15/216,128 patent/US9527074B2/en not_active Expired - Fee Related
- 2016-11-21 US US15/357,347 patent/US9638707B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2892751T3 (es) | Sistemas y métodos para el procesamiento de muestras en un recipiente cerrado y dispositivos relacionados | |
| US9701957B2 (en) | Reagent holder, and kits containing same | |
| ES2309413T3 (es) | Aparato modular para analisis. | |
| JP7756178B2 (ja) | 個別に動作する生物学的装置を用いた自動化分析システム、分析方法及び記憶媒体 | |
| KR20200136380A (ko) | 전자동 유전자 검사 장치 | |
| ES2876194T3 (es) | Dispositivo para reacción de amplificación de ácidos nucleicos | |
| HK1189661B (en) | Systems and methods for processing samples in a closed container, and related devices | |
| HK1189661A (en) | Systems and methods for processing samples in a closed container, and related devices | |
| US20240393359A1 (en) | Method for processing and analyzing sample in molecular diagnostic system | |
| US20230381770A1 (en) | Sample Preparation Cartridge and System | |
| WO2009074177A1 (en) | Forensic sample processor | |
| WO2022187609A9 (en) | Fluid handling device for a biological container |