ES2885080T3 - Composición inyectable que comprende fibroblastos para su utilización en el tratamiento de cardiopatías - Google Patents

Composición inyectable que comprende fibroblastos para su utilización en el tratamiento de cardiopatías Download PDF

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Publication number
ES2885080T3
ES2885080T3 ES18758465T ES18758465T ES2885080T3 ES 2885080 T3 ES2885080 T3 ES 2885080T3 ES 18758465 T ES18758465 T ES 18758465T ES 18758465 T ES18758465 T ES 18758465T ES 2885080 T3 ES2885080 T3 ES 2885080T3
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fibroblasts
cells
human
less
positive
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ES18758465T
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English (en)
Spanish (es)
Inventor
Takahiro Iwamiya
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Metcela Inc
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Metcela Inc
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33Fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES18758465T 2017-02-24 2018-02-23 Composición inyectable que comprende fibroblastos para su utilización en el tratamiento de cardiopatías Active ES2885080T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017033624 2017-02-24
PCT/JP2018/006795 WO2018155651A1 (ja) 2017-02-24 2018-02-23 線維芽細胞を含む心臓疾患を治療するための注射用組成物、及び治療用線維芽細胞の製造方法

Publications (1)

Publication Number Publication Date
ES2885080T3 true ES2885080T3 (es) 2021-12-13

Family

ID=63253929

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18758465T Active ES2885080T3 (es) 2017-02-24 2018-02-23 Composición inyectable que comprende fibroblastos para su utilización en el tratamiento de cardiopatías

Country Status (12)

Country Link
US (2) US11096969B2 (zh)
EP (1) EP3476395B1 (zh)
JP (2) JP6618066B2 (zh)
KR (1) KR102407387B1 (zh)
CN (1) CN109890398B (zh)
AU (1) AU2018223739B2 (zh)
CA (1) CA3032654A1 (zh)
DK (1) DK3476395T3 (zh)
ES (1) ES2885080T3 (zh)
IL (1) IL267958B2 (zh)
SG (1) SG11201900810WA (zh)
WO (1) WO2018155651A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112639082A (zh) 2018-08-29 2021-04-09 玛土撤拉有限公司 成纤维细胞的制备方法及g-csf阳性成纤维细胞群
CN109589337B (zh) * 2018-12-29 2022-04-26 南京艾尔普再生医学科技有限公司 心肌细胞制剂及其制备方法和应用
AU2021230209A1 (en) * 2020-03-04 2022-09-29 Metcela Inc. Fibroblast having enhanced erythropoietin production ability
EP4249585A1 (en) * 2022-03-25 2023-09-27 Technische Universität München - TUM Heart tissue models, method of producing heart tissue models and uses of heart tissue models

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
CN100435882C (zh) * 2002-05-08 2008-11-26 加利福尼亚大学董事会 用成纤维细胞治疗心律失常的系统和方法
US20040002740A1 (en) * 2002-05-08 2004-01-01 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US20040161412A1 (en) * 2002-08-22 2004-08-19 The Cleveland Clinic Foundation Cell-based VEGF delivery
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
WO2005046447A2 (en) * 2003-11-10 2005-05-26 Symphony Medical, Inc. Method to control ventricular rate in atrial fibrillation patients
US8513011B2 (en) * 2004-08-26 2013-08-20 Biotech Research Ventures Pte Limited Methods and compositions for culturing cardiomyocyte-like cells
ES2325715B1 (es) * 2007-08-03 2010-06-17 Genetrix, S.L. Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca.
JP5378743B2 (ja) 2008-09-30 2013-12-25 テルモ株式会社 医療用細胞シートの製造方法
WO2013028968A1 (en) * 2011-08-25 2013-02-28 Wisconsin Alumni Research Foundation 3-dimensional cardiac fibroblast derived extracellular matrix
WO2013137491A1 (ja) 2012-03-15 2013-09-19 国立大学法人京都大学 人工多能性幹細胞から心筋および血管系混合細胞群を製造する方法
WO2014039995A1 (en) * 2012-09-07 2014-03-13 Fibrocell Technologies, Inc. Fibroblast compositions for treating cardial damage after an infarct
GB201309057D0 (en) * 2013-05-20 2013-07-03 Cell Therapy Ltd Method
KR20150009655A (ko) * 2013-07-16 2015-01-27 학교법인 동아학숙 Gcp-2 유전자를 과발현하는 지방 간엽줄기세포를 포함하는 허혈성 질환 치료용 조성물
CA2954743C (en) * 2014-07-11 2022-03-15 Metcela Inc. Cardiac cell culture material

Also Published As

Publication number Publication date
KR102407387B1 (ko) 2022-06-10
US11096969B2 (en) 2021-08-24
CN109890398B (zh) 2024-01-16
JPWO2018155651A1 (ja) 2019-11-07
EP3476395B1 (en) 2021-07-21
US20190224250A1 (en) 2019-07-25
IL267958B2 (en) 2023-08-01
EP3476395A4 (en) 2020-02-26
IL267958B1 (en) 2023-04-01
DK3476395T3 (da) 2021-08-16
AU2018223739B2 (en) 2023-06-22
JP2019218408A (ja) 2019-12-26
SG11201900810WA (en) 2019-02-27
JP7072135B2 (ja) 2022-05-20
US20210346436A1 (en) 2021-11-11
CN109890398A (zh) 2019-06-14
EP3476395A1 (en) 2019-05-01
WO2018155651A1 (ja) 2018-08-30
KR20190117468A (ko) 2019-10-16
AU2018223739A1 (en) 2019-02-14
IL267958A (en) 2019-09-26
JP6618066B2 (ja) 2019-12-11
CA3032654A1 (en) 2018-08-30

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