ES2876350T3 - Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario - Google Patents

Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario Download PDF

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Publication number
ES2876350T3
ES2876350T3 ES15803364T ES15803364T ES2876350T3 ES 2876350 T3 ES2876350 T3 ES 2876350T3 ES 15803364 T ES15803364 T ES 15803364T ES 15803364 T ES15803364 T ES 15803364T ES 2876350 T3 ES2876350 T3 ES 2876350T3
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ES
Spain
Prior art keywords
composition
drug
thip
pharmaceutically acceptable
administration
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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ES15803364T
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English (en)
Spanish (es)
Inventor
Matthew During
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ovid Therapeutics Inc
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Ovid Therapeutics Inc
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
ES15803364T 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario Active ES2876350T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462008939P 2014-06-06 2014-06-06
PCT/US2015/034018 WO2015187851A1 (en) 2014-06-06 2015-06-03 Methods of increasing tonic inhibition and treating secondary insomnia

Publications (1)

Publication Number Publication Date
ES2876350T3 true ES2876350T3 (es) 2021-11-12

Family

ID=54767324

Family Applications (2)

Application Number Title Priority Date Filing Date
ES15803364T Active ES2876350T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario
ES18169211T Active ES2875742T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES18169211T Active ES2875742T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman

Country Status (20)

Country Link
US (11) US20150352085A1 (enExample)
EP (3) EP3372229B1 (enExample)
JP (4) JP2017516868A (enExample)
AR (1) AR100772A1 (enExample)
AU (4) AU2015269667B2 (enExample)
CA (1) CA2950845C (enExample)
CY (2) CY1124366T1 (enExample)
DK (2) DK3151832T3 (enExample)
ES (2) ES2876350T3 (enExample)
HR (2) HRP20210901T1 (enExample)
HU (2) HUE055400T2 (enExample)
IL (2) IL249287B (enExample)
LT (2) LT3151832T (enExample)
MX (2) MX380868B (enExample)
PL (2) PL3372229T3 (enExample)
PT (2) PT3372229T (enExample)
RS (2) RS62006B1 (enExample)
SI (2) SI3372229T1 (enExample)
SM (2) SMT202100340T1 (enExample)
WO (1) WO2015187851A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3372229T3 (pl) 2014-06-06 2021-10-04 Ovid Therapeutics, Inc. Sposoby zwiększenia hamowania tonicznego i leczenia zespołu angelmana
US10080898B2 (en) * 2015-05-29 2018-09-25 Medtronic, Inc. Simultaneous physiological sensing and stimulation with saturation detection
US10434308B2 (en) 2015-05-29 2019-10-08 Medtronic, Inc. Impedance matching and electrode conditioning in patient interface systems
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
MX391708B (es) 2015-07-17 2025-03-21 Ovid Therapeutics Inc Metodos para tratar trastornos del desarrollo con gaboxadol.
WO2018017639A1 (en) * 2016-07-19 2018-01-25 Georgia State University Research Foundation Methods for treating rett syndrome
MX2019001669A (es) 2016-08-11 2019-09-27 Ovid Therapeutics Inc Metodos y composiciones para el tratamiento de trastornos epilepticos.
AU2017363598A1 (en) * 2016-11-22 2019-05-23 Ovid Therapeutics Inc. Methods of treating developmental disorders and/or seizure disorders with flupirtine
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
KR20200047557A (ko) 2017-08-04 2020-05-07 오비드 테라퓨틱스 인크. 당뇨병 및 관련 질환들의 치료에서 가복사돌의 사용
US11181384B2 (en) * 2018-07-23 2021-11-23 Waymo Llc Verifying map data using challenge questions
KR20210062662A (ko) 2018-09-20 2021-05-31 오비드 테라퓨틱스 인크. 투렛 증후군, 틱들 및 말더듬의 치료를 위한 가복사돌의 사용
CN113395962A (zh) * 2018-11-21 2021-09-14 Certego治疗公司 加波沙朵用于降低自杀风险和快速缓解抑郁症
WO2020131856A1 (en) 2018-12-17 2020-06-25 Ovid Therapeutics Inc. Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
US20210015760A1 (en) * 2019-07-15 2021-01-21 Ovid Therapeutics Inc. Pharmaceutical formulations containing gaboxadol for therapeutic treatment
AU2020405060A1 (en) 2019-12-18 2022-06-09 Ovid Therapeutics Inc. Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
AU2021275863A1 (en) 2020-05-20 2023-02-02 Certego Therapeutics Inc. Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders
JP7600661B2 (ja) * 2020-12-11 2024-12-17 artience株式会社 貼付剤
US20240285562A1 (en) * 2023-02-17 2024-08-29 Ovid Therapeutics Inc. Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid in the treatment of multiple sclerosis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK270278A (da) 1977-06-20 1978-12-21 Krogsgaard Larsen P Cycliske aminosyrer
US4362731A (en) 1980-09-01 1982-12-07 Sandoz Ltd. Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4353910A (en) 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
DE19526864A1 (de) 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20050137222A1 (en) * 2003-12-18 2005-06-23 H. Lundbeck A/S Treatment of insomnia in human patients
MXPA06011325A (es) 2004-04-02 2006-12-15 Lundbeck & Co As H Tratamiento de la funcion respiratoria alterada con gaboxadol.
DE102005020882A1 (de) * 2005-05-04 2006-11-09 Dömling, Alexander, Dr. Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten
US20110046090A1 (en) * 2005-10-31 2011-02-24 Braincells Inc. Modulation of neurogenesis with gaba agents and gaba analogs
US20090143335A1 (en) 2007-10-29 2009-06-04 H. Lundbeck A/S Modified absorption formulation of gaboxadol
WO2009064928A1 (en) 2007-11-13 2009-05-22 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
CA2732636A1 (en) * 2008-09-01 2009-05-07 H. Lundbeck A/S Pharmaceutical composition comprising gaboxadol and an inhibitor of pat1 or oat
PL3372229T3 (pl) 2014-06-06 2021-10-04 Ovid Therapeutics, Inc. Sposoby zwiększenia hamowania tonicznego i leczenia zespołu angelmana
MX391708B (es) * 2015-07-17 2025-03-21 Ovid Therapeutics Inc Metodos para tratar trastornos del desarrollo con gaboxadol.
US9399034B1 (en) 2015-08-11 2016-07-26 Ovid Therapeutics Inc Methods of sedation during critical care treatment

Also Published As

Publication number Publication date
AU2020217342A1 (en) 2020-08-27
US20230051859A1 (en) 2023-02-16
US9339495B2 (en) 2016-05-17
HRP20210901T1 (hr) 2021-09-17
IL268960A (en) 2019-10-31
HRP20210902T1 (hr) 2021-09-17
AU2024202604A1 (en) 2024-05-09
US20180015076A1 (en) 2018-01-18
JP2017516868A (ja) 2017-06-22
US20160228418A1 (en) 2016-08-11
US9801864B2 (en) 2017-10-31
AU2020217342B2 (en) 2021-10-07
US20150352085A1 (en) 2015-12-10
IL249287B (en) 2021-03-25
CY1124366T1 (el) 2022-07-22
JP2021178836A (ja) 2021-11-18
US20170273956A1 (en) 2017-09-28
US20160038469A1 (en) 2016-02-11
AR100772A1 (es) 2016-11-02
MX2016016136A (es) 2017-07-05
CA2950845A1 (en) 2015-12-10
SMT202100340T1 (it) 2021-07-12
CY1124368T1 (el) 2022-07-22
CA2950845C (en) 2023-04-25
SI3372229T1 (sl) 2021-09-30
AU2015269667A1 (en) 2016-12-22
US11278529B2 (en) 2022-03-22
PL3151832T3 (pl) 2021-10-25
US9744159B2 (en) 2017-08-29
LT3372229T (lt) 2021-07-12
DK3372229T3 (da) 2021-06-14
DK3151832T3 (da) 2021-06-14
US20220016091A1 (en) 2022-01-20
EP3151832A1 (en) 2017-04-12
US20250025448A1 (en) 2025-01-23
JP2023123442A (ja) 2023-09-05
AU2015269667B2 (en) 2020-07-30
US20180303805A1 (en) 2018-10-25
AU2022200085A1 (en) 2022-02-03
US20170071917A1 (en) 2017-03-16
HUE055400T2 (hu) 2021-11-29
PL3372229T3 (pl) 2021-10-04
MX380868B (es) 2025-03-12
RS62007B1 (sr) 2021-07-30
EP3372229A1 (en) 2018-09-12
JP2020063264A (ja) 2020-04-23
US20170087133A1 (en) 2017-03-30
EP3795156A1 (en) 2021-03-24
RS62006B1 (sr) 2021-07-30
LT3151832T (lt) 2021-07-12
IL249287A0 (en) 2017-02-28
HUE055155T2 (hu) 2021-11-29
EP3151832A4 (en) 2018-01-17
IL268960B (en) 2021-05-31
EP3151832B1 (en) 2021-03-24
SMT202100343T1 (it) 2021-07-12
MX391502B (es) 2025-03-21
PT3372229T (pt) 2021-06-17
EP3372229B1 (en) 2021-03-24
ES2875742T3 (es) 2021-11-11
WO2015187851A1 (en) 2015-12-10
US9446028B2 (en) 2016-09-20
PT3151832T (pt) 2021-06-15
MX2020012404A (es) 2022-04-11
SI3151832T1 (sl) 2021-08-31

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